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3QEV
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BU of 3qev by Molmil
RB69 DNA Polymerase (L561A/S565G/Y567A) Ternary Complex with dCTP Opposite dT
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ...
Authors:Xia, S, Konigsberg, W.H, Wang, J.
Deposit date:2011-01-20
Release date:2012-01-25
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Hydrogen-Bonding Capability of Difluorotoluene Nucleoside in Replication Complexes
To be Published
5FHH
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BU of 5fhh by Molmil
Structure of human Pif1 helicase domain residues 200-641
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent DNA helicase PIF1, TETRAFLUOROALUMINATE ION
Authors:Zhou, X, Ren, W, Bharath, S.R, Song, H.
Deposit date:2015-12-22
Release date:2016-03-30
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structural and Functional Insights into the Unwinding Mechanism of Bacteroides sp Pif1
Cell Rep, 14, 2016
1Y77
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BU of 1y77 by Molmil
Complete RNA Polymerase II elongation complex with substrate analogue GMPCPP
Descriptor: 5'-D(*AP*AP*GP*TP*AP*CP*T)-3', 5'-D(P*AP*GP*TP*AP*CP*TP*TP*AP*CP*T*CP*GP*CP*CP*TP*GP*GP*TP*CP*TP*G)-3', 5'-R(*AP*AP*GP*AP*CP*CP*AP*GP*GP*C)-3', ...
Authors:Kettenberger, H, Armache, K.-J, Cramer, P.
Deposit date:2004-12-08
Release date:2005-01-04
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:Complete RNA Polymerase II Elongation Complex Structure and Its Interactions with NTP and TFIIS
Mol.Cell, 16, 2004
1SAX
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BU of 1sax by Molmil
Three-dimensional structure of s.aureus methicillin-resistance regulating transcriptional repressor meci in complex with 25-bp ds-DNA
Descriptor: 5'-d(CAAAATTACAACTGTAATATCGGAG)-3', 5'-d(GCTCCGATATTACAGTTGTAATTTT)-3', Methicillin resistance regulatory protein mecI, ...
Authors:Garcia-Castellanos, R, Mallorqui-Fernandez, G, Marrero, A, Potempa, J, Coll, M, Gomis-Ruth, F.X.
Deposit date:2004-02-09
Release date:2004-04-27
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:On the transcriptional regulation of methicillin resistance: MecI repressor in complex with its operator
J.Biol.Chem., 279, 2004
4LMG
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BU of 4lmg by Molmil
Crystal structure of AFT2 in complex with DNA
Descriptor: 5'-D(*AP*AP*GP*TP*GP*CP*AP*CP*CP*CP*AP*TP*T)-3', 5'-D(*TP*AP*AP*TP*GP*GP*GP*TP*GP*CP*AP*CP*T)-3', Iron-regulated transcriptional activator AFT2, ...
Authors:Poor, C.B, Sanishvili, R, Schuermann, J.P, He, C.
Deposit date:2013-07-10
Release date:2014-03-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Molecular mechanism and structure of the Saccharomyces cerevisiae iron regulator Aft2.
Proc.Natl.Acad.Sci.USA, 111, 2014
4HTU
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BU of 4htu by Molmil
Structure of 5-chlorouracil modified A:U base pair
Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*(UCL)P*CP*GP*CP*G)-3'), GLYCEROL, ...
Authors:Patra, A, Egli, M.
Deposit date:2012-11-01
Release date:2012-12-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.489 Å)
Cite:Structure, stability and function of 5-chlorouracil modified A:U and G:U base pairs.
Nucleic Acids Res., 41, 2013
1LFU
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BU of 1lfu by Molmil
NMR Solution Structure of the Extended PBX Homeodomain Bound to DNA
Descriptor: 5'-D(*GP*CP*GP*CP*AP*TP*GP*AP*TP*TP*GP*CP*CP*C)-3', 5'-D(*GP*GP*GP*CP*AP*AP*TP*CP*AP*TP*GP*CP*GP*C)-3', homeobox protein PBX1
Authors:Sprules, T, Green, N, Featherstone, M, Gehring, K.
Deposit date:2002-04-12
Release date:2003-01-14
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Lock and Key Binding of the HOX YPWM Peptide to the PBX Homeodomain
J.Biol.Chem., 278, 2003
3QEW
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BU of 3qew by Molmil
RB69 DNA Polymerase (L561A/S565G/Y567A) Ternary Complex with dDTP Opposite dT
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ...
Authors:Xia, S, Konigsberg, W.H, Wang, J.
Deposit date:2011-01-20
Release date:2012-01-25
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Hydrogen-Bonding Capability of Difluorotoluene Nucleoside in Replication Complexes
To be Published
4A09
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BU of 4a09 by Molmil
Structure of hsDDB1-drDDB2 bound to a 15 bp CPD-duplex (purine at D-1 position) at 3.1 A resolution (CPD 2)
Descriptor: 5'-D(*CP*CP*TP*GP*CP*TP*CP*CP*TP*TP*TP*CP*AP*CP*CP*C)-3', 5'-D(*GP*GP*TP*GP*AP*AP*AP*(TTD)P*AP*GP*CP*AP*GP*GP)-3', CALCIUM ION, ...
Authors:Scrima, A, Fischer, E.S, Iwai, S, Gut, H, Thoma, N.H.
Deposit date:2011-09-08
Release date:2011-11-30
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The Molecular Basis of Crl4(Ddb2/Csa) Ubiquitin Ligase Architecture, Targeting, and Activation
Cell(Cambridge,Mass.), 147, 2011
5JKT
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BU of 5jkt by Molmil
vaccinia virus D4 P173G mutant /A20(1-50)
Descriptor: ACETATE ION, DNA polymerase processivity factor component A20, SULFATE ION, ...
Authors:Contesto-Richefeu, C, Tarbouriech, N, Brazzolotto, X, Burmeister, W.P, Peyrefitte, C.N, Iseni, F.
Deposit date:2016-04-26
Release date:2016-09-14
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Structural analysis of point mutations at the Vaccinia virus A20/D4 interface.
Acta Crystallogr.,Sect.F, 72, 2016
7S8D
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BU of 7s8d by Molmil
Structure of DNA-free SgrAI
Descriptor: CALCIUM ION, SgraIR restriction enzyme
Authors:Horton, N.C.
Deposit date:2021-09-17
Release date:2022-08-24
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Pretransition state and apo structures of the filament-forming enzyme SgrAI elucidate mechanisms of activation and substrate specificity.
J.Biol.Chem., 298, 2022
6N3A
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BU of 6n3a by Molmil
SegA-long, conformation of TDP-43 low complexity domain segment A long
Descriptor: TAR DNA-binding protein 43, segA long small
Authors:Cao, Q, Boyer, D.R, Sawaya, M.R, Eisenberg, D.S.
Deposit date:2018-11-14
Release date:2019-06-26
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Cryo-EM structures of four polymorphic TDP-43 amyloid cores.
Nat.Struct.Mol.Biol., 26, 2019
6N3C
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BU of 6n3c by Molmil
SegB, conformation of TDP-43 low complexity domain segment A
Descriptor: TAR DNA-binding protein 43
Authors:Cao, Q, Boyer, D.R, Sawaya, M.R, Eisenberg, D.S.
Deposit date:2018-11-14
Release date:2019-06-26
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Cryo-EM structures of four polymorphic TDP-43 amyloid cores.
Nat.Struct.Mol.Biol., 26, 2019
6N3B
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BU of 6n3b by Molmil
SegA-asym, conformation of TDP-43 low complexity domain segment A asym
Descriptor: TAR DNA-binding protein 43
Authors:Cao, Q, Boyer, D.R, Sawaya, M.R, Eisenberg, D.S.
Deposit date:2018-11-14
Release date:2019-06-26
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Cryo-EM structures of four polymorphic TDP-43 amyloid cores.
Nat.Struct.Mol.Biol., 26, 2019
6O2L
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BU of 6o2l by Molmil
NMR structure of the 2:1 complex of a carbazole derivative BMVC bound to c-MYC G-quadruplex
Descriptor: 3,6-bis[(E)-2-(1-methylpyridin-1-ium-4-yl)ethenyl]-9H-carbazole, DNA (5'-D(*TP*GP*AP*GP*GP*GP*TP*GP*GP*GP*TP*AP*GP*GP*GP*TP*GP*GP*GP*TP*AP*A)-3')
Authors:Lin, C, Liu, W, Yang, D.
Deposit date:2019-02-24
Release date:2019-10-23
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structures of 1:1 and 2:1 complexes of BMVC and MYC promoter G-quadruplex reveal a mechanism of ligand conformation adjustment for G4-recognition.
Nucleic Acids Res., 47, 2019
6J9C
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BU of 6j9c by Molmil
Crystal structure of Arabidopsis thaliana transcription factor LEC2-DNA complex
Descriptor: B3 domain-containing transcription factor LEC2, DNA (5'-D(*CP*AP*AP*TP*CP*CP*AP*TP*GP*CP*AP*GP*AP*AP*T)-3'), DNA (5'-D(*GP*AP*TP*TP*CP*TP*GP*CP*AP*TP*GP*GP*AP*TP*T)-3')
Authors:Hu, H, Du, J.
Deposit date:2019-01-22
Release date:2019-05-29
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.102 Å)
Cite:Embryonic resetting of the parental vernalized state by two B3 domain transcription factors in Arabidopsis.
Nat.Plants, 5, 2019
6J9B
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BU of 6j9b by Molmil
Arabidopsis FUS3-DNA complex
Descriptor: B3 domain-containing transcription factor FUS3, DNA (5'-D(*AP*AP*TP*CP*CP*AP*TP*GP*CP*AP*GP*AP*AP*TP*C)-3'), DNA (5'-D(*AP*TP*TP*CP*TP*GP*CP*AP*TP*GP*GP*AP*TP*TP*G)-3')
Authors:Hu, H, Du, J.
Deposit date:2019-01-22
Release date:2019-05-29
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Embryonic resetting of the parental vernalized state by two B3 domain transcription factors in Arabidopsis.
Nat.Plants, 5, 2019
1T2T
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BU of 1t2t by Molmil
Crystal structure of the DNA-binding domain of intron endonuclease I-TevI with operator site
Descriptor: 5'-D(*AP*AP*TP*TP*AP*AP*AP*GP*GP*GP*CP*AP*GP*TP*CP*CP*TP*AP*CP*AP*A)-3', 5'-D(*TP*TP*TP*GP*TP*AP*GP*GP*AP*CP*TP*GP*CP*CP*CP*TP*TP*TP*AP*AP*T)-3', Intron-associated endonuclease 1, ...
Authors:Edgell, D.R, Derbyshire, V, Van Roey, P, LaBonne, S, Stanger, M.J, Li, Z, Boyd, T.M, Shub, D.A, Belfort, M.
Deposit date:2004-04-22
Release date:2004-09-07
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Intron-encoded homing endonuclease I-TevI also functions as a transcriptional autorepressor.
Nat.Struct.Mol.Biol., 11, 2004
3Q1M
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BU of 3q1m by Molmil
Crystal Structure of BmrR Dimer bound to DNA and the ligand 4-amino-quinaldine
Descriptor: 2-methylquinolin-4-amine, 23 bp promoter DNA, Multidrug-efflux transporter 1 regulator
Authors:Bachas, S, Eginton, C, Gunio, G, Wade, H.
Deposit date:2010-12-17
Release date:2011-06-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural contributions to multidrug recognition in the multidrug resistance (MDR) gene regulator, BmrR.
Proc.Natl.Acad.Sci.USA, 108, 2011
7C0M
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BU of 7c0m by Molmil
Human cGAS-nucleosome complex
Descriptor: Cyclic GMP-AMP synthase, DNA (145-MER), Histone H2A type 1-B/E, ...
Authors:Kujirai, T, Zierhut, C, Takizawa, Y, Kim, R, Negishi, L, Uruma, N, Hirai, S, Funabiki, H, Kurumizaka, H.
Deposit date:2020-05-01
Release date:2020-09-16
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural basis for the inhibition of cGAS by nucleosomes.
Science, 370, 2020
7F25
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BU of 7f25 by Molmil
Crystal structure of SSB from Salmonella enterica serovar Typhimurium LT2.
Descriptor: Single-stranded DNA-binding protein 1
Authors:Luo, R.H, Huang, Y.H, Huang, C.Y.
Deposit date:2021-06-10
Release date:2022-05-04
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.87 Å)
Cite:Crystal Structure of an SSB Protein from Salmonella enterica and Its Inhibition by Flavanonol Taxifolin.
Int J Mol Sci, 23, 2022
8OUY
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BU of 8ouy by Molmil
Human RAD51B-RAD51C-RAD51D-XRCC2 (BCDX2) complex, 3.4 A resolution
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DNA repair protein RAD51 homolog 2, ...
Authors:Greenhough, L.A, Liang, C.C, West, S.C.
Deposit date:2023-04-25
Release date:2023-06-21
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure and function of the RAD51B-RAD51C-RAD51D-XRCC2 tumour suppressor.
Nature, 619, 2023
4Q47
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BU of 4q47 by Molmil
Structure of the DrRecQ Catalytic Core in complex with ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA helicase RecQ, ZINC ION
Authors:Chen, S.C, Yang, C.S, Chen, Y.
Deposit date:2014-04-14
Release date:2015-05-20
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.899 Å)
Cite:Crystal structure of Deinococcus radiodurans RecQ helicase catalytic core domain: the interdomain flexibility.
Biomed Res Int, 2014, 2014
1P6R
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BU of 1p6r by Molmil
Solution structure of the DNA binding domain of the repressor BlaI.
Descriptor: Penicillinase repressor
Authors:Melckebeke, H.V, Vreuls, C, Gans, P, Llabres, G, Filee, P, Joris, B, Simorre, J.P.
Deposit date:2003-04-30
Release date:2003-12-09
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structural study of BlaI: implications for the repression of genes involved in beta-lactam antibiotic resistance.
J.Mol.Biol., 333, 2003
6ZUE
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BU of 6zue by Molmil
Crystal structure of human DDB1 bound to human DCAF1 (amino acid residues 1046-1396)
Descriptor: DDB1- and CUL4-associated factor 1, DNA damage-binding protein 1
Authors:Schwefel, D, Taylor, I.A.
Deposit date:2020-07-22
Release date:2021-07-28
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.094 Å)
Cite:Structural insights into Cullin4-RING ubiquitin ligase remodelling by Vpr from simian immunodeficiency viruses.
Plos Pathog., 17, 2021

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