Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

6KH9
DownloadVisualize
BU of 6kh9 by Molmil
Solution structure of bovine insulin amyloid intermediate-1
Descriptor: Insulin A chain, Insulin B chain
Authors:Ratha, B.N, Kar, R.K, Brender, J.B, Bhunia, A.
Deposit date:2019-07-14
Release date:2020-08-12
Last modified:2020-11-18
Method:SOLUTION NMR
Cite:High-resolution structure of a partially folded insulin aggregation intermediate.
Proteins, 88, 2020
6K59
DownloadVisualize
BU of 6k59 by Molmil
Structure of Glargine insulin in 20% acetic acid-d4 (pH 1.9)
Descriptor: Glargine Insulin Chain-A, Glargine insulin Chain-B
Authors:Ratha, B.N, Kar, R.K, Bhunia, A.
Deposit date:2019-05-28
Release date:2020-05-06
Method:SOLUTION NMR
Cite:Molecular Details of a Salt Bridge and Its Role in Insulin Fibrillation by NMR and Raman Spectroscopic Analysis.
J.Phys.Chem.B, 124, 2020
6KHA
DownloadVisualize
BU of 6kha by Molmil
Solution structure of bovine insulin amyloid intermediate-2
Descriptor: Insulin A chain, Insulin B chain
Authors:Ratha, B.N, Kar, R.K, Brender, J.B, Bhunia, A.
Deposit date:2019-07-14
Release date:2020-08-12
Last modified:2020-11-18
Method:SOLUTION NMR
Cite:High-resolution structure of a partially folded insulin aggregation intermediate.
Proteins, 88, 2020
6INS
DownloadVisualize
BU of 6ins by Molmil
X-RAY ANALYSIS OF THE SINGLE CHAIN B29-A1 PEPTIDE-LINKED INSULIN MOLECULE. A COMPLETELY INACTIVE ANALOGUE
Descriptor: INSULIN, ZINC ION
Authors:Derewenda, U, Derewenda, Z, Dodson, E.J, Dodson, G.G, Bing, X, Markussen, J.
Deposit date:1992-11-25
Release date:1994-01-31
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-ray analysis of the single chain B29-A1 peptide-linked insulin molecule. A completely inactive analogue.
J.Mol.Biol., 220, 1991
8PI4
DownloadVisualize
BU of 8pi4 by Molmil
Crystal structure of human insulin desB30 precursor with an Alanine-Methionine-Lysine C-peptide in dimer (T2) conformation
Descriptor: Insulin B chain,Insulin A chain
Authors:Johansson, E, Schluckebier, G.
Deposit date:2023-06-21
Release date:2023-11-08
Last modified:2024-04-17
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Molecular engineering of insulin for recombinant expression in yeast.
Trends Biotechnol, 42, 2024
8PJH
DownloadVisualize
BU of 8pjh by Molmil
Crystal structure of human insulin desB30 precursor with an Aspartate-Glycine-Lysine C-peptide in dimer (T2) conformation
Descriptor: Insulin
Authors:Schluckebier, G, Johansson, E.
Deposit date:2023-06-23
Release date:2023-11-08
Last modified:2024-04-17
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Molecular engineering of insulin for recombinant expression in yeast.
Trends Biotechnol, 42, 2024
8PI5
DownloadVisualize
BU of 8pi5 by Molmil
Crystal structure of human insulin desB30 precursor with an Alanine-Methionine-Lysine C-peptide in hexamer (T3R3) conformation
Descriptor: CHLORIDE ION, Insulin B chain,Insulin A chain, RESORCINOL, ...
Authors:Johansson, E, Schluckebier, G.
Deposit date:2023-06-21
Release date:2023-11-08
Last modified:2024-04-17
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Molecular engineering of insulin for recombinant expression in yeast.
Trends Biotechnol, 42, 2024
8PI6
DownloadVisualize
BU of 8pi6 by Molmil
Crystal structure of the monomeric zinc free human insulin A22K, B3E, B26E, B29R, desB30 precursor with a Ser-Glu-Asp-Trp-Trp-Arg C-peptide and a Glu-Glu-Gly-Glu-Pro-Arg N-terminal extension
Descriptor: Insulin B chain,Insulin A chain
Authors:Johansson, E, Schluckebier, G.
Deposit date:2023-06-21
Release date:2023-11-08
Last modified:2024-04-17
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Molecular engineering of insulin for recombinant expression in yeast.
Trends Biotechnol, 42, 2024
8PJC
DownloadVisualize
BU of 8pjc by Molmil
Crystal structure of human insulin desB30 precursor with an Alanine-Alanine-Lysine C-peptide in dimer (T2) conformation
Descriptor: Insulin
Authors:Schluckebier, G, Johansson, E.
Deposit date:2023-06-23
Release date:2023-11-08
Last modified:2024-04-17
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Molecular engineering of insulin for recombinant expression in yeast.
Trends Biotechnol, 42, 2024
8RRP
DownloadVisualize
BU of 8rrp by Molmil
Insulin Icodec - A14E B16H B25H B29Ne-C20 diacid-LgGlu-2xAdo desB30 human insulin
Descriptor: ACETATE ION, Insulin, Insulin B chain
Authors:Schluckebier, G, Johansson, E.
Deposit date:2024-01-23
Release date:2024-07-10
Last modified:2024-07-31
Method:X-RAY DIFFRACTION (2 Å)
Cite:Enhanced disulphide bond stability contributes to the once-weekly profile of insulin icodec.
Nat Commun, 15, 2024
8SBD
DownloadVisualize
BU of 8sbd by Molmil
Cryo-EM structure of insulin amyloid-like fibril that is composed of two antiparallel protofilaments
Descriptor: Insulin A chain, Insulin B chain
Authors:Wang, L.W, Hall, C, Uchikawa, E, Chen, D.L, Choi, E, Zhang, X.W, Bai, X.C.
Deposit date:2023-04-03
Release date:2023-08-30
Last modified:2023-09-27
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural basis of insulin fibrillation.
Sci Adv, 9, 2023
8RVT
DownloadVisualize
BU of 8rvt by Molmil
Structure of full-length human insulin fibrils
Descriptor: Insulin A chain, Insulin B chain
Authors:Bardiaux, B, Suladze, S, Reif, B.
Deposit date:2024-02-02
Release date:2024-05-29
Last modified:2024-06-12
Method:SOLID-STATE NMR
Cite:Atomic resolution structure of full-length human insulin fibrils.
Proc.Natl.Acad.Sci.USA, 121, 2024
3TT8
DownloadVisualize
BU of 3tt8 by Molmil
Crystal Structure Analysis of Cu Human Insulin Derivative
Descriptor: COPPER (II) ION, INSULIN A-CHAIN, INSULIN B-CHAIN
Authors:Prugovecki, B, Matkovic-Calogovic, D.
Deposit date:2011-09-14
Release date:2011-10-19
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.12 Å)
Cite:Crystal Structure Analysis of Cu Human Insulin Derivative
To be Published
3U4N
DownloadVisualize
BU of 3u4n by Molmil
A novel covalently linked insulin dimer
Descriptor: Insulin A chain, Insulin B chain
Authors:Norrman, M, Vinther, T.N.
Deposit date:2011-10-10
Release date:2012-04-11
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Novel covalently linked insulin dimer engineered to investigate the function of insulin dimerization.
Plos One, 7, 2012
2C8Q
DownloadVisualize
BU of 2c8q by Molmil
insuline(1sec) and UV laser excited fluorescence
Descriptor: INSULIN A CHAIN, INSULIN B CHAIN
Authors:Vernede, X, Lavault, B, Ohana, J, Nurizzo, D, Joly, J, Jacquamet, L, Felisaz, F, Cipriani, F, Bourgeois, D.
Deposit date:2005-12-06
Release date:2006-03-08
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Uv Laser-Excited Fluorescence as a Tool for the Visualization of Protein Crystals Mounted in Loops.
Acta Crystallogr.,Sect.D, 62, 2006
2BN1
DownloadVisualize
BU of 2bn1 by Molmil
Insulin after a high dose x-ray burn
Descriptor: INSULIN A CHAIN, INSULIN B CHAIN
Authors:Nanao, M.H, Ravelli, R.B.
Deposit date:2005-03-18
Release date:2005-09-07
Last modified:2013-04-03
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Improving Radiation-Damage Substructures for Rip.
Acta Crystallogr.,Sect.D, 61, 2005
3T2A
DownloadVisualize
BU of 3t2a by Molmil
TMAO-grown cubic insulin (porcine)
Descriptor: Insulin A chain, Insulin B chain, trimethylamine oxide
Authors:Cahn, J, Venkat, M, Marshall, H, Juers, D.
Deposit date:2011-07-22
Release date:2011-12-28
Last modified:2012-01-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The use of trimethylamine N-oxide as a primary precipitating agent and related methylamine osmolytes as cryoprotective agents for macromolecular crystallography.
Acta Crystallogr.,Sect.D, 68, 2012
2BN3
DownloadVisualize
BU of 2bn3 by Molmil
Insulin before a high dose x-ray burn
Descriptor: INSULIN
Authors:Nanao, M.H, Ravelli, R.B.
Deposit date:2005-03-18
Release date:2005-09-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Improving Radiation-Damage Substructures for Rip.
Acta Crystallogr.,Sect.D, 61, 2005
3V19
DownloadVisualize
BU of 3v19 by Molmil
Forestalling insulin fibrillation by insertion of a chiral clamp mechanism-based application of protein engineering to global health
Descriptor: CHLORIDE ION, Insulin, PHENOL, ...
Authors:Wan, Z.L, Hua, Q.X, Wickramasinghe, N.P, Huang, K, Petkova, A.T, Hu, S.Q, Phillips, N.B, Yeh, I.J, Whittake, J, Ismail-Beigi, F, Katsoyyannis, P.G, Tycko, R, Weiss, M.A.
Deposit date:2011-12-09
Release date:2012-12-12
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Forestalling insulin fibrillation by insertion of a chiral clamp mechanism-based application of protein engineering to global health
To be Published
2AIY
DownloadVisualize
BU of 2aiy by Molmil
R6 HUMAN INSULIN HEXAMER (SYMMETRIC), NMR, 20 STRUCTURES
Descriptor: PHENOL, PROTEIN (INSULIN)
Authors:O'Donoghue, S.I, Chang, X, Abseher, R, Nilges, M, Led, J.J.
Deposit date:1998-12-28
Release date:2000-02-28
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Unraveling the symmetry ambiguity in a hexamer: calculation of the R6 human insulin structure.
J.Biomol.NMR, 16, 2000
3W80
DownloadVisualize
BU of 3w80 by Molmil
Crystal structure of dodecamer human insulin with double C-axis length of the hexamer 2 Zn insulin cell
Descriptor: Insulin, ZINC ION
Authors:Murayoshi, M, Sasaki, K, Sakabe, N, Sakabe, K.
Deposit date:2013-03-11
Release date:2013-07-03
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal structure of dodecamer insulin with double C-axis length of the hexamer 2 Zn insulin celll
To be Published
3W7Y
DownloadVisualize
BU of 3w7y by Molmil
0.92A structure of 2Zn human insulin at 100K
Descriptor: Insulin, ZINC ION
Authors:Sakabe, N, Sakabe, K, Sasaki, K, Murayoshi, M.
Deposit date:2013-03-11
Release date:2013-07-03
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (0.92 Å)
Cite:0.92A structure of 2Zn human insulin at 100K
To be Published
2EFA
DownloadVisualize
BU of 2efa by Molmil
Neutron crystal structure of cubic insulin at pD6.6
Descriptor: Insulin
Authors:Ishikawa, T, Tanaka, I, Niimura, N.
Deposit date:2007-02-22
Release date:2008-01-22
Last modified:2023-10-25
Method:NEUTRON DIFFRACTION (2.7 Å)
Cite:A neutron crystallographic analysis of a cubic porcine insulin at pD 6.6
Chem.Phys., 345, 2008
2C8R
DownloadVisualize
BU of 2c8r by Molmil
insuline(60sec) and UV laser excited fluorescence
Descriptor: INSULIN A CHAIN, INSULIN B CHAIN
Authors:Vernede, X, Lavault, B, Ohana, J, Nurizzo, D, Joly, J, Jacquamet, L, Felisaz, F, Cipriani, F, Bourgeois, D.
Deposit date:2005-12-06
Release date:2006-03-08
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Uv Laser-Excited Fluorescence as a Tool for the Visualization of Protein Crystals Mounted in Loops.
Acta Crystallogr.,Sect.D, 62, 2006
3V1G
DownloadVisualize
BU of 3v1g by Molmil
Forestalling insulin fibrillation by insertion of a chiral clamp mechanism-based application of protein engineering to global health
Descriptor: CHLORIDE ION, Insulin, PHENOL, ...
Authors:Wan, Z.L, Hua, Q.X, Wickramasinghe, N.P, Huang, K, Petkova, A.T, Hu, S.Q, Phillips, N.B, Yeh, I.J, Whittake, J, Ismail-Beigi, F, Katsoyyannis, P.G, Tycko, R, Weiss, M.A.
Deposit date:2011-12-09
Release date:2012-12-12
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Forestalling insulin fibrillation by insertion of a chiral clamp mechanism-based application of protein engineering to global health
To be Published

223532

건을2024-08-07부터공개중

PDB statisticsPDBj update infoContact PDBjnumon