8YTS
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![BU of 8yts by Molmil](/molmil-images/mine/8yts) | The structure of the cytochrome c546/556 from Thioalkalivibrio paradoxus with unusual UV-Vis spectral features at atomic resolution | Descriptor: | Cytochrome C, HEME C | Authors: | Varfolomeeva, L.A, Solovieva, A.Y, Dergousova, N.I, Boyko, K.M, Tikhonova, T.V, Popov, V.O. | Deposit date: | 2024-03-26 | Release date: | 2024-04-24 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | The structure of the cytochrome c546/556 from Thioalkalivibrio paradoxus with unusual UV-Vis spectral features at atomic resolution To Be Published
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9ERX
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![BU of 9erx by Molmil](/molmil-images/mine/9erx) | Structural basis of D9-THC analog activity at the Cannabinoid 1 receptor | Descriptor: | (6aR,10aR)-9-(hydroxymethyl)-6,6-dimethyl-3-(2-methyloctan-2-yl)-6a,7,10,10a-tetrahydrobenzo[c]chromen-1-ol, Antibody ScFv16 Fab fragment, Cannabinoid receptor 1, ... | Authors: | Thorsen, T.S, Kulkarni, Y, Boggild, A, Drace, T, Nissen, P, Gajhede, M, Boesen, T, Kastrup, J.S, Gloriam, D. | Deposit date: | 2024-03-25 | Release date: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural basis of Delta 9 -THC analog activity at the Cannabinoid 1 receptor. Res Sq, 2024
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8YRG
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![BU of 8yrg by Molmil](/molmil-images/mine/8yrg) | CryoEM structure of fospropofol-bound MRGPRX4-Gq complex | Descriptor: | Gs-mini-Gq chimera, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Cao, C, Fay, J.F, Roth, B.L. | Deposit date: | 2024-03-21 | Release date: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.14 Å) | Cite: | MRGPRX4 mediates phospho-drug-associated pruritus in a humanized mouse model. Sci Transl Med, 16, 2024
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9B3R
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![BU of 9b3r by Molmil](/molmil-images/mine/9b3r) | The structure of human cardiac F-actin | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha cardiac muscle 1, ... | Authors: | Doran, M.H, Sousa, D, Rynkiewicz, M.J, Lehman, W, Cammarato, A. | Deposit date: | 2024-03-20 | Release date: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structure of human cardiac actin To Be Published
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9EPV
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![BU of 9epv by Molmil](/molmil-images/mine/9epv) | Crystal structure of human Casein Kinase II subunit alpha (CK2a1) in complex with allosteric ligand FGC333 | Descriptor: | 1,2-ETHANEDIOL, 5-[[2-[(3-chloranyl-4-phenyl-phenyl)methylamino]-7-azaspiro[3.5]nonan-7-yl]sulfonyl]-1,3-dimethyl-benzimidazol-2-one, Casein kinase II subunit alpha, ... | Authors: | Kraemer, A, Greco, F, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2024-03-20 | Release date: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of human Casein Kinase II subunit alpha (CK2a1) in complex with allosteric ligand FGC333 To Be Published
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8YR4
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![BU of 8yr4 by Molmil](/molmil-images/mine/8yr4) | Cryo-EM structure of the human ABCB6 in complex with Cd(II):Phytochelatin 2 | Descriptor: | ATP-binding cassette sub-family B member 6, CADMIUM ION, GAMMA-D-GLUTAMIC ACID, ... | Authors: | Choi, S.H, Lee, S.S, Lee, H.Y, Kim, S, Kim, J.W, Jin, M.S. | Deposit date: | 2024-03-20 | Release date: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Cryo-EM structure of cadmium-bound human ABCB6. Commun Biol, 7, 2024
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9B4H
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![BU of 9b4h by Molmil](/molmil-images/mine/9b4h) | Chlamydomonas reinhardtii mastigoneme filament | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C-type lectin domain-containing protein, Tyrosine-protein kinase ephrin type A/B receptor-like domain-containing protein, ... | Authors: | Dai, J, Ma, M, Zhang, R, Brown, A. | Deposit date: | 2024-03-20 | Release date: | 2024-04-10 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Mastigoneme structure reveals insights into the O-linked glycosylation code of native hydroxyproline-rich helices. Cell, 2024
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9EPX
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![BU of 9epx by Molmil](/molmil-images/mine/9epx) | Crystal structure of human Casein Kinase II subunit alpha (CK2a1) in complex with allosteric ligand FGC3331 | Descriptor: | 1,2-ETHANEDIOL, 7-[(2-chloranyl-1,3-benzothiazol-6-yl)sulfonyl]-~{N}-[(3-chloranyl-4-phenyl-phenyl)methyl]-7-azaspiro[3.5]nonan-2-amine, Casein kinase II subunit alpha, ... | Authors: | Kraemer, A, Greco, F, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2024-03-20 | Release date: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structure of human Casein Kinase II subunit alpha (CK2a1) in complex with allosteric ligand FGC3331 To Be Published
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9EPY
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![BU of 9epy by Molmil](/molmil-images/mine/9epy) | Crystal structure of human Casein Kinase II subunit alpha (CK2a1) in complex with allosteric ligand FGC3330 | Descriptor: | 1,2-ETHANEDIOL, Casein kinase II subunit alpha, SULFATE ION, ... | Authors: | Kraemer, A, Greco, F, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2024-03-20 | Release date: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Crystal structure of human Casein Kinase II subunit alpha (CK2a1) in complex with allosteric ligand FGC3330 To Be Published
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9EPZ
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![BU of 9epz by Molmil](/molmil-images/mine/9epz) | Crystal structure of human Casein Kinase II subunit alpha (CK2a1) in complex with allosteric ligand FGC3337 | Descriptor: | 1,2-ETHANEDIOL, Casein kinase II subunit alpha, SULFATE ION, ... | Authors: | Kraemer, A, Greco, F, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2024-03-20 | Release date: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Crystal structure of human Casein Kinase II subunit alpha (CK2a1) in complex with allosteric ligand FGC3337 To Be Published
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9EPW
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![BU of 9epw by Molmil](/molmil-images/mine/9epw) | |
9EQ1
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![BU of 9eq1 by Molmil](/molmil-images/mine/9eq1) | Crystal structure of human Casein Kinase II subunit alpha (CK2a1) in complex with allosteric ligand FGJM24 | Descriptor: | 1,2-ETHANEDIOL, Casein kinase II subunit alpha, SULFATE ION, ... | Authors: | Kraemer, A, Greco, F, Moeckel, J, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2024-03-20 | Release date: | 2024-05-01 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal structure of human Casein Kinase II subunit alpha (CK2a1) in complex with allosteric ligand FGJM24 To Be Published
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9EQ0
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![BU of 9eq0 by Molmil](/molmil-images/mine/9eq0) | Crystal structure of human Casein Kinase II subunit alpha (CK2a1) in complex with allosteric ligand FGJG12 | Descriptor: | Casein kinase II subunit alpha, SULFATE ION, ~{N}-[4-[(3-chloranyl-4-phenyl-phenyl)methylamino]butyl]isoquinoline-5-sulfonamide | Authors: | Kraemer, A, Greco, F, Gerninghaus, J, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2024-03-20 | Release date: | 2024-05-01 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | Crystal structure of human Casein Kinase II subunit alpha (CK2a1) in complex with allosteric ligand FGJG12 To Be Published
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9B3Q
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![BU of 9b3q by Molmil](/molmil-images/mine/9b3q) | The structure of the human cardiac F-actin mutant A331P | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha cardiac muscle 1, ... | Authors: | Doran, M.H, Sousa, D, Rynkiewicz, M.J, Lehman, W, Cammarato, A. | Deposit date: | 2024-03-20 | Release date: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structure of human cardiac actin To Be Published
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8YR3
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![BU of 8yr3 by Molmil](/molmil-images/mine/8yr3) | Cryo-EM structure of the human ABCB6 in complex with Cd(II):GSH | Descriptor: | ATP-binding cassette sub-family B member 6, CADMIUM ION, GLUTATHIONE | Authors: | Choi, S.H, Lee, S.S, Lee, H.Y, Kim, S, Kim, J.W, Jin, M.S. | Deposit date: | 2024-03-20 | Release date: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Cryo-EM structure of cadmium-bound human ABCB6. Commun Biol, 7, 2024
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9B3D
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![BU of 9b3d by Molmil](/molmil-images/mine/9b3d) | mDia1 in the middle of F-actin | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Palmer, N.J, Barrie, K.R, Dominguez, R. | Deposit date: | 2024-03-19 | Release date: | 2024-05-29 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.41 Å) | Cite: | Mechanisms of actin filament severing and elongation by formins. Nature, 2024
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9B35
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![BU of 9b35 by Molmil](/molmil-images/mine/9b35) | Ligand-binding and transmembrane domains of kainate receptor GluK2 in the open state, a complex with agonist glutamate and positive allosteric modulator BPAM344 | Descriptor: | GLUTAMIC ACID, Glutamate receptor ionotropic, kainate 2 | Authors: | Nadezhdin, K.D, Gangwar, S.P, Sobolevsky, A.I. | Deposit date: | 2024-03-18 | Release date: | 2024-05-22 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Kainate receptor channel opening and gating mechanism. Nature, 630, 2024
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9B37
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![BU of 9b37 by Molmil](/molmil-images/mine/9b37) | Open state of kainate receptor GluK2 in complex with agonist glutamate and positive allosteric modulator BPAM344 bound to one concanavalin A dimer. Composite map. | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Nadezhdin, K.D, Gangwar, S.P, Sobolevsky, A.I. | Deposit date: | 2024-03-18 | Release date: | 2024-05-22 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (6.66 Å) | Cite: | Kainate receptor channel opening and gating mechanism. Nature, 630, 2024
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9B36
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![BU of 9b36 by Molmil](/molmil-images/mine/9b36) | Open state of kainate receptor GluK2 in complex with agonist glutamate and positive allosteric modulator BPAM344 bound to two concanavalin A dimers. Composite map. | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Nadezhdin, K.D, Gangwar, S.P, Sobolevsky, A.I. | Deposit date: | 2024-03-18 | Release date: | 2024-05-22 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (4.29 Å) | Cite: | Kainate receptor channel opening and gating mechanism. Nature, 630, 2024
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9B38
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![BU of 9b38 by Molmil](/molmil-images/mine/9b38) | Kainate receptor GluK2 in complex with agonist glutamate with pseudo 4-fold symmetrical ligand-binding domain layer | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, ... | Authors: | Nadezhdin, K.D, Gangwar, S.P, Sobolevsky, A.I. | Deposit date: | 2024-03-18 | Release date: | 2024-05-22 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3.36 Å) | Cite: | Kainate receptor channel opening and gating mechanism. Nature, 630, 2024
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9B39
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![BU of 9b39 by Molmil](/molmil-images/mine/9b39) | Kainate receptor GluK2 in complex with agonist glutamate with asymmetric ligand-binding domain layer | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, ... | Authors: | Nadezhdin, K.D, Gangwar, S.P, Sobolevsky, A.I. | Deposit date: | 2024-03-18 | Release date: | 2024-05-22 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3.84 Å) | Cite: | Kainate receptor channel opening and gating mechanism. Nature, 630, 2024
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9EOJ
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![BU of 9eoj by Molmil](/molmil-images/mine/9eoj) | Vertebrate microtubule-capping gamma-tubulin ring complex | Descriptor: | Gamma-tubulin complex component, Gamma-tubulin complex component 3 homolog, Gamma-tubulin complex component 6, ... | Authors: | Vermeulen, B.J.A, Pfeffer, S. | Deposit date: | 2024-03-15 | Release date: | 2024-04-17 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (17 Å) | Cite: | gamma-TuRC asymmetry induces local protofilament mismatch at the RanGTP-stimulated microtubule minus end. Embo J., 43, 2024
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9ENZ
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![BU of 9enz by Molmil](/molmil-images/mine/9enz) | |
9EO8
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![BU of 9eo8 by Molmil](/molmil-images/mine/9eo8) | |
9B27
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![BU of 9b27 by Molmil](/molmil-images/mine/9b27) | |