PDB: 35140 resultsInfo pagesStatus searchChemie searchBIRD

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2M0F	Solution Structure of Miz-1 zinc finger 7 Descriptor: ZINC ION, Zinc finger and BTB domain-containing protein 17 Authors: Bernard, D, Bedard, M, Bilodeau, J, Lavigne, P. Deposit date: 2012-10-24 Release date: 2012-11-14 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: NMR Structure Note: Solution Structure of Miz-1 Zinc Fingers 5 to 7 To be Published
2ML9	Solution structure of YSCUCN in a micellar complex with SDS Descriptor: Yop proteins translocation protein U Authors: Weise, C.F, Wolf-Watz, M. Deposit date: 2014-02-20 Release date: 2014-11-26 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: Negatively charged lipid membranes promote a disorder-order transition in the Yersinia YscU protein. Biophys.J., 107, 2014
6IF1	Crystal structure of Ube2K and K48-linked di-ubiquitin complex Descriptor: Ubiquitin, Ubiquitin-conjugating enzyme E2 K Authors: Lee, J.-G, Youn, H.-S, Lee, Y, An, J.Y, Park, K.R, Kang, J.Y, Lim, J.J, Eom, S.H. Deposit date: 2018-09-18 Release date: 2018-11-21 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.466 Å) Cite: Crystal structure of the Ube2K/E2-25K and K48-linked di-ubiquitin complex provides structural insight into the mechanism of K48-specific ubiquitin chain synthesis. Biochem. Biophys. Res. Commun., 506, 2018
2LWP	The NMR solution structure of the the ubiquitin homology domain of mouse BAG-1 Descriptor: BAG family molecular chaperone regulator 1 Authors: Huang, H, Yu, C. Deposit date: 2012-08-05 Release date: 2013-06-19 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: The NMR solution structure of the ubiquitin homology domain of Bcl-2-associated athanogene 1 (BAG-1-UBH) from Mus musculus. Biochem.Biophys.Res.Commun., 431, 2013
4FZY	Exonuclease X in complex with 12bp blunt-ended dsDNA Descriptor: DNA (5'-D(*TP*GP*TP*AP*GP*AP*TP*TP*CP*GP*AP*G)-3'), DNA (5'-D(P*CP*TP*CP*GP*AP*AP*TP*CP*TP*AP*CP*A)-3'), Exodeoxyribonuclease 10, ... Authors: Wang, T, Sun, H, Cheng, F, Bi, L, Jiang, T. Deposit date: 2012-07-08 Release date: 2013-07-03 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Recognition and processing of double-stranded DNA by ExoX, a distributive 3'-5' exonuclease Nucleic Acids Res., 41, 2013
6ID0	Cryo-EM structure of a human intron lariat spliceosome prior to Prp43 loaded (ILS1 complex) at 2.9 angstrom resolution Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, CWF19-like protein 2, Cell division cycle 5-like protein, ... Authors: Zhang, X, Zhan, X, Yan, C, Shi, Y. Deposit date: 2018-09-07 Release date: 2019-03-13 Last modified: 2020-10-14 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Structures of the human spliceosomes before and after release of the ligated exon. Cell Res., 29, 2019
4WNW	Human Cytochrome P450 2D6 Thioridazine Complex Descriptor: 10-{2-[(2R)-1-methylpiperidin-2-yl]ethyl}-2-(methylsulfanyl)-10H-phenothiazine, Cytochrome P450 2D6, NICKEL (II) ION, ... Authors: Wang, A, Stout, C.D, Johnson, E.F. Deposit date: 2014-10-14 Release date: 2015-01-14 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (3.299 Å) Cite: Contributions of Ionic Interactions and Protein Dynamics to Cytochrome P450 2D6 (CYP2D6) Substrate and Inhibitor Binding. J.Biol.Chem., 290, 2015
5KW6	Two Tandem RRM Domains of PUF60 Bound to an AdML Pre-mRNA 3' Splice Site Analogue with a Modified Binding-Site Nucleic Acid Base Descriptor: DNA (30-MER), Poly(U)-binding-splicing factor PUF60 Authors: Crichlow, G.V, Hsiao, H.-H, Albright, R, Lolis, E.J, Braddock, D.T. Deposit date: 2016-07-15 Release date: 2017-08-23 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.91 Å) Cite: Unraveling the mechanism of recognition of the 3' splice site of the adenovirus major late promoter intron by the alternative splicing factor PUF60. Plos One, 15, 2020
8H7G	Cryo-EM structure of the human SAGA complex Descriptor: Ataxin-7, STAGA complex 65 subunit gamma, Splicing factor 3B subunit 3, ... Authors: Huang, J, Zhang, Y. Deposit date: 2022-10-20 Release date: 2022-12-14 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Cryo-EM structure of human SAGA transcriptional coactivator complex. Cell Discov, 8, 2022
2LWI	Solution structure of H-RasT35S mutant protein in complex with Kobe2601 Descriptor: 2-(2,4-dinitrophenyl)-N-(4-fluorophenyl)hydrazinecarbothioamide, GTPase HRas, MAGNESIUM ION, ... Authors: Araki, M, Tamura, A, Shima, F, Kataoka, T. Deposit date: 2012-08-01 Release date: 2013-05-22 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: In silico discovery of small-molecule Ras inhibitors that display antitumor activity by blocking the Ras-effector interaction. Proc.Natl.Acad.Sci.USA, 110, 2013
8HMS	Crystal Structure of PKM2 mutant C474S Descriptor: 1,2-ETHANEDIOL, 1,6-di-O-phosphono-beta-D-fructofuranose, GLYCEROL, ... Authors: Upadhyay, S, Kumar, A, Patel, A.K. Deposit date: 2022-12-05 Release date: 2023-01-11 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structural and mechanistic insights into cancer patient-derived mutations in Pyruvate Kinase muscle isoform 2 To Be Published
8HMQ	Crystal Structure of PKM2 mutant P403A Descriptor: 1,2-ETHANEDIOL, 1,6-di-O-phosphono-beta-D-fructofuranose, GLYCEROL, ... Authors: Upadhyay, S, Kumar, A, Patel, A.K. Deposit date: 2022-12-05 Release date: 2023-01-11 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structural and mechanistic insights into cancer patient-derived mutations in Pyruvate Kinase muscle isoform 2 To Be Published
8HMR	Crystal Structure of PKM2 mutant L144P Descriptor: 1,2-ETHANEDIOL, 1,6-di-O-phosphono-beta-D-fructofuranose, MAGNESIUM ION, ... Authors: Upadhyay, S, Kumar, A, Patel, A.K. Deposit date: 2022-12-05 Release date: 2023-01-11 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structural and mechanistic insights into cancer patient-derived mutations in Pyruvate Kinase muscle isoform 2 To Be Published
2MDG	Solution NMR Structure of Zinc finger protein 423 from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR7298F Descriptor: ZINC ION, Zinc finger protein 423 Authors: Pederson, K, Lee, D, Kohan, E, Janjua, H, Xiao, R, Everett, J.K, Acton, T.B, Montelione, G.T, Prestegard, J.H, Northeast Structural Genomics Consortium (NESG) Deposit date: 2013-09-10 Release date: 2013-09-25 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: Solution NMR Structure of Zinc finger protein 423 from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR7298F To be Published
8H8C	Type VI secretion system effector RhsP in its post-autoproteolysis and dimeric form Descriptor: C-terminal peptide from Putative Rhs-family protein, Putative Rhs-family protein Authors: Tang, L, Dong, S.Q, Rasheed, N, Wu, H.W, Zhou, N.K, Li, H.D, Wang, M.L, Zheng, J, He, J, Chao, W.C.H. Deposit date: 2022-10-22 Release date: 2023-01-18 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY (3.36 Å) Cite: Vibrio parahaemolyticus prey targeting requires autoproteolysis-triggered dimerization of the type VI secretion system effector RhsP. Cell Rep, 41, 2022
8HMU	Crystal Structure of PKM2 mutant R516C Descriptor: 1,2-ETHANEDIOL, 1,6-di-O-phosphono-beta-D-fructofuranose, GLYCEROL, ... Authors: Upadhyay, S, Kumar, A, Patel, A.K. Deposit date: 2022-12-05 Release date: 2023-01-11 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structural and mechanistic insights into cancer patient-derived mutations in Pyruvate Kinase muscle isoform 2 To Be Published
8H8B	Type VI secretion system effector RhsP in its pre-autoproteolysis and monomeric form Descriptor: Putative Rhs-family protein Authors: Tang, L, Dong, S.Q, Rasheed, N, Wu, H.W, Zhou, N.K, Li, H.D, Wang, M.L, Zheng, J, He, J, Chao, W.C.H. Deposit date: 2022-10-22 Release date: 2023-01-18 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY (3.16 Å) Cite: Vibrio parahaemolyticus prey targeting requires autoproteolysis-triggered dimerization of the type VI secretion system effector RhsP. Cell Rep, 41, 2022
2M6T	NMR solution structure ensemble of 3-4D mutant domain 11 IGF2R Descriptor: Insulin-like growth factor 2 receptor variant Authors: Strickland, M, Williams, C, Richards, E, Minnall, L, Crump, M.P, Frago, S, Hughes, J, Garner, L, Hoppe, H, Rezgui, D, Zaccheo, O.J, Prince, S.N, Hassan, A.B, Whittaker, S. Deposit date: 2013-04-09 Release date: 2014-10-15 Last modified: 2016-06-01 Method: SOLUTION NMR Cite: Functional evolution of IGF2:IGF2R domain 11 binding generates novel structural interactions and a specific IGF2 antagonist. Proc.Natl.Acad.Sci.USA, 113, 2016
8H8A	Type VI secretion system effector RhsP in its post-autoproteolysis and monomeric form Descriptor: C-terminal peptide from Putative Rhs-family protein, Putative Rhs-family protein Authors: Tang, L, Dong, S.Q, Rasheed, N, Wu, H.W, Zhou, N.K, Li, H.D, Wang, M.L, Zheng, J, He, J, Chao, W.C.H. Deposit date: 2022-10-22 Release date: 2023-01-18 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY (3.25 Å) Cite: Vibrio parahaemolyticus prey targeting requires autoproteolysis-triggered dimerization of the type VI secretion system effector RhsP. Cell Rep, 41, 2022
6EJX	The metal ion-dependent adhesion site (MIDAS) of the alphaMbeta2 integrin Mac-1 I-domain promiscuously and competitively binds multiple ligands in the regulation of Leukocyte function Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... Authors: Emsley, J, Saleem, M. Deposit date: 2017-09-24 Release date: 2018-10-24 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural basis of the leukocyte integrin Mac-1 I-domain interactions with the platelet glycoprotein Ib. Blood Adv, 3, 2019
7S0F	Isoproterenol bound beta1 adrenergic receptor in complex with heterotrimeric Gi protein Descriptor: Beta1-Adrenergic Receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... Authors: Paknejad, N, Alegre, K.O, Su, M, Lou, J.S, Huang, J, Jordan, K.D, Eng, E.T, Meyerson, J.R, Hite, R.K, Huang, X.Y. Deposit date: 2021-08-30 Release date: 2021-11-17 Last modified: 2021-12-01 Method: ELECTRON MICROSCOPY (2.96 Å) Cite: Structural basis and mechanism of activation of two different families of G proteins by the same GPCR. Nat.Struct.Mol.Biol., 28, 2021
7S0G	Isoproterenol bound beta1 adrenergic receptor in complex with heterotrimeric Gi/s chimera protein Descriptor: Beta1-Adrenergic Receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... Authors: Paknejad, N, Alegre, K.O, Su, M, Lou, J.S, Huang, J, Jordan, K.D, Eng, E.T, Meyerson, J.R, Hite, R.K, Huang, X.Y. Deposit date: 2021-08-30 Release date: 2021-11-17 Last modified: 2021-12-01 Method: ELECTRON MICROSCOPY (3.86 Å) Cite: Structural basis and mechanism of activation of two different families of G proteins by the same GPCR. Nat.Struct.Mol.Biol., 28, 2021
7Z3X	Crystal structure of FIR RRM1-2 Y115F mutant bound to FUSE ssDNA Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*TP*TP*T)-3'), DNA (5'-D(P*GP*TP*())-3'), ... Authors: Ni, X, Chaikuad, A, Knapp, S, Structural Genomics Consortium (SGC) Deposit date: 2022-03-02 Release date: 2022-11-09 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Crystal structure of FIR RRM1-2 Y115F mutant bound to FUSE ssDNA To Be Published
2DCO	S1P4 First Extracellular Loop Peptidomimetic Descriptor: S1P4 First Extracellular Loop Peptidomimetic Authors: Pham, T.C.T, Kriwacki, R.W, Parrill, A.L. Deposit date: 2006-01-11 Release date: 2007-01-23 Last modified: 2021-11-10 Method: SOLUTION NMR Cite: Peptide design and structural characterization of a GPCR loop mimetic Biopolymers, 86, 2007
2DGU	Solution structure of the RNA binding domain in Heterogeneous nuclear ribonucleoprotein Q Descriptor: Heterogeneous nuclear ribonucleoprotein Q Authors: Abe, C, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2006-03-15 Release date: 2006-09-15 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: Solution structure of the RNA binding domain in Heterogeneous nuclear ribonucleoprotein Q To be Published

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