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5X0I
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BU of 5x0i by Molmil
Crystal structure of PKM2 R399E mutant complexed with FBP and serine
Descriptor: 1,6-di-O-phosphono-beta-D-fructofuranose, MAGNESIUM ION, POTASSIUM ION, ...
Authors:Wang, W.C, Chen, T.J.
Deposit date:2017-01-20
Release date:2018-01-31
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:Mutations in the PKM2 exon-10 region are associated with reduced allostery and increased nuclear translocation.
Commun Biol, 2, 2019
2WGT
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BU of 2wgt by Molmil
Structure of human adenovirus serotype 37 fibre head in complex with a sialic acid derivative, O-Methyl 5-N-propaonyl-3,5-dideoxy-D- glycero-a-D-galacto-2-nonulopyranosylonic acid
Descriptor: 3,5-dideoxy-5-(propanoylamino)-D-glycero-alpha-D-galacto-non-2-ulopyranosonic acid, FIBER PROTEIN, ZINC ION
Authors:Johansson, S, Nilsson, E, Qian, W, Guilligay, D, Crepin, T, Cusack, S, Arnberg, N, Elofsson, M.
Deposit date:2009-04-27
Release date:2009-11-24
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Design, Synthesis, and Evaluation of N-Acyl Modified Sialic Acids as Inhibitors of Adenoviruses Causing Epidemic Keratoconjunctivitis.
J.Med.Chem., 52, 2009
4ZN7
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BU of 4zn7 by Molmil
Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in complex with Diethylstilbestrol
Descriptor: DIETHYLSTILBESTROL, Estrogen receptor, Nuclear receptor coactivator 2
Authors:Nwachukwu, J.C, Srinivasan, S, Zheng, Y, Wang, S, Min, J, Dong, C, Liao, Z, Cavett, V, Nowak, J, Houtman, R, Carlson, K.E, Josan, J.S, Elemento, O, Katzenellenbogen, J.A, Zhou, H.B, Nettles, K.W.
Deposit date:2015-05-04
Release date:2016-05-04
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.934 Å)
Cite:Predictive features of ligand-specific signaling through the estrogen receptor.
Mol.Syst.Biol., 12, 2016
7WOT
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BU of 7wot by Molmil
Cryo-EM structure of the inner ring monomer of the Saccharomyces cerevisiae nuclear pore complex
Descriptor: Nucleoporin NIC96, Nucleoporin NSP1, Nucleoporin NUP157, ...
Authors:Li, Z.Q, Chen, S.J.B, Zhao, L, Sui, S.F.
Deposit date:2022-01-22
Release date:2022-04-13
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3.73 Å)
Cite:Near-atomic structure of the inner ring of the Saccharomyces cerevisiae nuclear pore complex.
Cell Res., 32, 2022
5WA8
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BU of 5wa8 by Molmil
Human Histidine Triad Nucleotide Binding Protein 1 (hHint1) H112N mutant nucleoside L-Ala phosphoramidate substrate complex
Descriptor: CHLORIDE ION, Histidine triad nucleotide-binding protein 1, [(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-~{N}-[(2~{S})-1-methoxy-1-oxidanylidene-propan-2-yl]phosphonamidic acid
Authors:Maize, K.M, Finzel, B.C.
Deposit date:2017-06-26
Release date:2017-10-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:A Crystal Structure Based Guide to the Design of Human Histidine Triad Nucleotide Binding Protein 1 (hHint1) Activated ProTides.
Mol. Pharm., 14, 2017
5WAA
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BU of 5waa by Molmil
Human Histidine Triad Nucleotide Binding Protein 1 (hHint1) C84R mutant
Descriptor: CHLORIDE ION, Histidine triad nucleotide-binding protein 1
Authors:Maize, K.M, Finzel, B.C.
Deposit date:2017-06-26
Release date:2018-06-06
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.098 Å)
Cite:Structure and Functional Characterization of Human Histidine Triad Nucleotide-Binding Protein 1 Mutations Associated with Inherited Axonal Neuropathy with Neuromyotonia.
J. Mol. Biol., 430, 2018
4R0V
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BU of 4r0v by Molmil
[FeFe]-hydrogenase Oxygen Inactivation is Initiated by the Modification and Degradation of the H cluster 2Fe Subcluster
Descriptor: ARSENIC, CHLORIDE ION, Fe-hydrogenase, ...
Authors:Swanson, S.D, Ratzloff, M.W, Mulder, D.W, Artz, J.H, Ghose, S, Hoffman, A, White, S, Zadvornyy, O.A, Broderick, J.B, Bothner, B, King, P.W, Peters, J.W.
Deposit date:2014-08-01
Release date:2015-01-28
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:[FeFe]-Hydrogenase Oxygen Inactivation Is Initiated at the H Cluster 2Fe Subcluster.
J.Am.Chem.Soc., 137, 2015
7WOO
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BU of 7woo by Molmil
Cryo-EM structure of the inner ring protomer of the Saccharomyces cerevisiae nuclear pore complex
Descriptor: Nucleoporin NIC96, Nucleoporin NSP1, Nucleoporin NUP157, ...
Authors:Li, Z.Q, Chen, S.J.B, Zhao, L, Sui, S.F.
Deposit date:2022-01-22
Release date:2022-04-13
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3.71 Å)
Cite:Near-atomic structure of the inner ring of the Saccharomyces cerevisiae nuclear pore complex.
Cell Res., 32, 2022
6T18
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BU of 6t18 by Molmil
ASR Alternansucrase in complex with oligoalternan
Descriptor: Alternansucrase, CALCIUM ION, alpha-D-glucopyranose-(1-3)-alpha-D-glucopyranose-(1-6)-alpha-D-glucopyranose, ...
Authors:Cioci, G, Molina, M, Moulis, C, Remaud-Simeon, M.
Deposit date:2019-10-03
Release date:2020-06-17
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:A specific oligosaccharide-binding site in the alternansucrase catalytic domain mediates alternan elongation.
J.Biol.Chem., 295, 2020
4KZL
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BU of 4kzl by Molmil
Crystal structure of human tankyrase 2 in complex with 4'-fluoro flavone
Descriptor: 2-(4-fluorophenyl)-4H-chromen-4-one, GLYCEROL, SULFATE ION, ...
Authors:Narwal, M, Haikarainen, T, Lehtio, L.
Deposit date:2013-05-30
Release date:2013-10-30
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Discovery of tankyrase inhibiting flavones with increased potency and isoenzyme selectivity.
J.Med.Chem., 56, 2013
2VX8
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BU of 2vx8 by Molmil
Vamp7 longin domain Hrb peptide complex
Descriptor: CHLORIDE ION, NUCLEOPORIN-LIKE PROTEIN RIP, VESICLE-ASSOCIATED MEMBRANE PROTEIN 7
Authors:Evans, P.R, Owen, D.J, Luzio, J.P.
Deposit date:2008-07-01
Release date:2008-09-16
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Molecular Basis for the Sorting of the Snare Vamp7 Into Endocytic Clathrin-Coated Vesicles by the Arfgap Hrb.
Cell(Cambridge,Mass.), 134, 2008
4ZIE
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BU of 4zie by Molmil
Crystal Structure of core/latch dimer of Bax in complex with BimBH3
Descriptor: 1,2-ETHANEDIOL, Apoptosis regulator BAX, Bcl-2-like protein 11
Authors:Krishna Kumar, K, Robin, A.Y, Westphal, D, Wardak, A.Z, Thompson, G.V, Dewson, G, Colman, P.M, Czabotar, P.E.
Deposit date:2015-04-28
Release date:2015-07-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.797 Å)
Cite:Crystal structure of Bax bound to the BH3 peptide of Bim identifies important contacts for interaction.
Cell Death Dis, 6, 2015
4ZIH
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BU of 4zih by Molmil
Crystal Structure of core/latch dimer of Bax in complex with BimBH3mini
Descriptor: Apoptosis regulator BAX, Bcl-2-like protein 11
Authors:Robin, A.Y, Krishna Kumar, K, Westphal, D, Wardak, A.Z, Thompson, G.V, Dewson, G, Colman, P.M, Czabotar, P.E.
Deposit date:2015-04-28
Release date:2015-07-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of Bax bound to the BH3 peptide of Bim identifies important contacts for interaction.
Cell Death Dis, 6, 2015
5HPS
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BU of 5hps by Molmil
System-wide modulation of HECT E3 ligases with selective ubiquitin variant probes: WWP1 and UbV P1.1
Descriptor: Ubiquitin variant P1.1, WWP1 HECT
Authors:Wu, K.-P, Mercredi, P.Y, Schulman, B.A.
Deposit date:2016-01-20
Release date:2016-03-16
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes.
Mol.Cell, 62, 2016
4ZKV
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BU of 4zkv by Molmil
Crystal structure of human histidine triad nucleotide-binding protein 1 (hHINT1) refined to 1.92A at P21 space group
Descriptor: Histidine triad nucleotide-binding protein 1, SULFATE ION
Authors:Dolot, R.M, Seda, A, Nawrot, B.
Deposit date:2015-04-30
Release date:2016-03-02
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Crystallographic studies of the complex of human HINT1 protein with a non-hydrolyzable analog of Ap4A.
Int.J.Biol.Macromol., 87, 2016
4MI8
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BU of 4mi8 by Molmil
Crystal structure of the complex of murine gamma-herpesvirus 68 Bcl-2 homolog M11 and a Beclin 1 BH3 domain-derived peptide
Descriptor: Bcl-2 homolog (Gene 16?), Beclin-1, SULFATE ION
Authors:Su, M, Mei, Y, Sinha, S.
Deposit date:2013-08-30
Release date:2014-01-29
Last modified:2016-02-17
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Targeting gamma-herpesvirus 68 Bcl-2-mediated down-regulation of autophagy.
J.Biol.Chem., 289, 2014
5Y6B
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BU of 5y6b by Molmil
Crystal structure of ZmASCH Y47F mutant protein from Zymomonas mobilis
Descriptor: Helix-turn-helix domain-containing protein
Authors:Park, S.-Y, Kim, J.-S.
Deposit date:2017-08-11
Release date:2018-07-18
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of an ASCH protein from Zymomonas mobilis and its ribonuclease activity specific for single-stranded RNA.
Sci Rep, 7, 2017
3D1D
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BU of 3d1d by Molmil
Hexagonal crystal structure of Tas3 C-terminal alpha motif
Descriptor: RNA-induced transcriptional silencing complex protein tas3
Authors:Li, H, Patel, D.J.
Deposit date:2008-05-05
Release date:2009-04-21
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:An alpha motif at Tas3 C terminus mediates RITS cis spreading and promotes heterochromatic gene silencing.
Mol.Cell, 34, 2009
3D45
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BU of 3d45 by Molmil
Crystal structure of mouse PARN in complex with m7GpppG
Descriptor: 7N-METHYL-8-HYDROGUANOSINE-5'-MONOPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, Poly(A)-specific ribonuclease PARN
Authors:Wu, M, Song, H.
Deposit date:2008-05-13
Release date:2009-03-17
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis of m(7)GpppG binding to poly(A)-specific ribonuclease.
Structure, 17, 2009
8I5Z
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BU of 8i5z by Molmil
LDH Mutant P101Q-(An unexpected single-point mutation triggers the unleashing of catalytic potential of a NADH-dependent dehydrogenase)
Descriptor: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein
Authors:Liu, J.Q.
Deposit date:2023-01-26
Release date:2023-09-06
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Characterization of the Pro101Gln mutation that enhances the catalytic performance of T. indicus NADH-dependent d-lactate dehydrogenase.
Structure, 31, 2023
5YGB
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BU of 5ygb by Molmil
Crystal structure of drosophila melanogaster Papi extended Tudor domain mutant - D287A
Descriptor: GH18329p
Authors:Zhang, Y.H, Huang, Y.
Deposit date:2017-09-22
Release date:2018-03-14
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural insights into the sequence-specific recognition of Piwi byDrosophilaPapi
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5W7W
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BU of 5w7w by Molmil
Crystal Structure of FHA domain of human APLF
Descriptor: Aprataxin and PNK-like factor, FORMIC ACID, SODIUM ION
Authors:Pedersen, L.C, Kim, K, London, R.E.
Deposit date:2017-06-21
Release date:2018-05-02
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.348 Å)
Cite:Characterization of the APLF FHA-XRCC1 phosphopeptide interaction and its structural and functional implications.
Nucleic Acids Res., 45, 2017
7UZF
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BU of 7uzf by Molmil
Rat Kidney V-ATPase with SidK, State 1
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATPase H+-transporting V1 subunit A, ATPase H+-transporting V1 subunit D, ...
Authors:Rubinstein, J.L, Abbas, Y.M.
Deposit date:2022-05-09
Release date:2023-11-22
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure of V-ATPase with NCOA7B
To Be Published
7UZI
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BU of 7uzi by Molmil
Rat Kidney V-ATPase lacking subunit H, with SidK and NCOA7B, State 2
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATPase H+-transporting V1 subunit A, ATPase H+-transporting V1 subunit D, ...
Authors:Rubinstein, J.L, Abbas, Y.M.
Deposit date:2022-05-09
Release date:2023-11-22
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structure of V-ATPase with NCOA7B
To Be Published
7UZH
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BU of 7uzh by Molmil
Rat Kidney V-ATPase with SidK, State 2
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATPase H+-transporting V1 subunit A, ATPase H+-transporting V1 subunit D, ...
Authors:Rubinstein, J.L, Abbas, Y.M.
Deposit date:2022-05-09
Release date:2023-11-22
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure of V-ATPase with NCOA7B
To Be Published

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