Crystal structure of mouse PARN in complex with m7GpppG

Summary for 3D45

DescriptorPoly(A)-specific ribonuclease PARN, 7N-METHYL-8-HYDROGUANOSINE-5'-MONOPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, ... (4 entities in total)
Functional Keywordsparn, cap analogue, exonuclease, hydrolase, magnesium, metal-binding, nonsense-mediated mrna decay, nuclease, nucleus, phosphoprotein, rna-binding
Biological sourceMus musculus (mouse)
Cellular locationNucleus Q8VDG3
Total number of polymer chains2
Total molecular weight118365
Wu, M.,Song, H. (deposition date: 2008-05-13, release date: 2009-03-17, Last modification date: 2018-01-24)
Primary citation
Wu, M.,Nilsson, P.,Henriksson, N.,Niedzwiecka, A.,Lim, M.K.,Cheng, Z.,Kokkoris, K.,Virtanen, A.,Song, H.
Structural basis of m(7)GpppG binding to poly(A)-specific ribonuclease.
Structure, 17:276-286, 2009
PubMed: 19217398 (PDB entries with the same primary citation)
DOI: 10.1016/j.str.2008.11.012
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliersRSRZ outliers212.4%14.6%2.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 3d45
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Molmil generated image of 3d45
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Molmil generated image of 3d45
rotated about y axis by 90°
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