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8V98
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BU of 8v98 by Molmil
GII.24 Loreto 1972 norovirus protruding domain
Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Capsid protein VP1
Authors:Kher, G, Prewitt, A, Pancera, M, Hansman, G.
Deposit date:2023-12-07
Release date:2024-06-19
Last modified:2024-07-31
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Development of a broad-spectrum therapeutic Fc-nanobody for human noroviruses.
J.Virol., 98, 2024
8V46
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BU of 8v46 by Molmil
CryoEM structure of AriA-AriB complex (Form I)
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, AriA antitoxin, AriB, ...
Authors:Deep, A, Corbett, K.D.
Deposit date:2023-11-28
Release date:2024-06-26
Last modified:2024-08-28
Method:ELECTRON MICROSCOPY (3.09 Å)
Cite:Architecture and activation mechanism of the bacterial PARIS defence system.
Nature, 2024
8W0X
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BU of 8w0x by Molmil
Crystal structure of broadly neutralizing antibody hcab40 in complex with Hepatitis C virus envelope glycoprotein E2 ectodomain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein E2, ...
Authors:Flyak, A.I, Wilcox, X.E.
Deposit date:2024-02-14
Release date:2024-03-27
Last modified:2024-04-17
Method:X-RAY DIFFRACTION (3.12 Å)
Cite:Convergent evolution and targeting of diverse E2 epitopes by human broadly neutralizing antibodies are associated with HCV clearance.
Immunity, 57, 2024
3MDK
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BU of 3mdk by Molmil
Structure of stringent starvation protein A (sspA) from Pseudomonas putida
Descriptor: Stringent starvation protein A
Authors:Ramagopal, U.A, Toro, R, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2010-03-30
Release date:2010-05-12
Last modified:2021-02-10
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structure of stringent starvation protein A (sspA) from Pseudomonas putida
To be published
3MDW
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BU of 3mdw by Molmil
The structure of N-formimino-L-Glutamate Iminohydrolase from Pseudomonas aeruginosa complexed with N-formimino-L-Aspartate
Descriptor: GLYCEROL, N-[(E)-iminomethyl]-L-aspartic acid, N-formimino-L-Glutamate Iminohydrolase, ...
Authors:Fedorov, A.A, Fedorov, E.V, Marti-Arbona, R, Raushel, F.M, Almo, S.C.
Deposit date:2010-03-30
Release date:2011-03-09
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.8979 Å)
Cite:Structure of N-Formimino-l-glutamate Iminohydrolase from Pseudomonas aeruginosa.
Biochemistry, 54, 2015
8W0Y
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BU of 8w0y by Molmil
Crystal structure of broadly neutralizing antibody hcab17 in complex with Hepatitis C virus envelope glycoprotein E2 ectodomain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein E2, ...
Authors:Flyak, A.I, Wilcox, X.E.
Deposit date:2024-02-14
Release date:2024-03-27
Last modified:2024-04-17
Method:X-RAY DIFFRACTION (3.31 Å)
Cite:Convergent evolution and targeting of diverse E2 epitopes by human broadly neutralizing antibodies are associated with HCV clearance.
Immunity, 57, 2024
8W8F
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BU of 8w8f by Molmil
human co-transcriptional RNA capping enzyme RNGTT-CMTR1
Descriptor: Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1, DNA (36-MER), DNA (45-MER), ...
Authors:Li, Y, Wang, Q, Xu, Y, Li, Z.
Deposit date:2023-09-02
Release date:2024-04-10
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structures of co-transcriptional RNA capping enzymes on paused transcription complex.
Nat Commun, 15, 2024
3MMR
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BU of 3mmr by Molmil
Structure of Plasmodium falciparum Arginase in complex with ABH
Descriptor: 2(S)-AMINO-6-BORONOHEXANOIC ACID, Arginase, BETA-MERCAPTOETHANOL, ...
Authors:Dowling, D.P, Ilies, M, Olszewski, K.L, Portugal, S, Mota, M.M, Llinas, M, Christianson, D.W.
Deposit date:2010-04-20
Release date:2010-06-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Crystal structure of arginase from Plasmodium falciparum and implications for L-arginine depletion in malarial infection .
Biochemistry, 49, 2010
8W0W
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BU of 8w0w by Molmil
Crystal structure of broadly neutralizing antibody hcab64 in complex with Hepatitis C virus envelope glycoprotein E2 ectodomain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein E2, ...
Authors:Flyak, A.I, Wilcox, X.E.
Deposit date:2024-02-14
Release date:2024-03-27
Last modified:2024-04-17
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Convergent evolution and targeting of diverse E2 epitopes by human broadly neutralizing antibodies are associated with HCV clearance.
Immunity, 57, 2024
3MOS
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BU of 3mos by Molmil
The structure of human Transketolase
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, SODIUM ION, ...
Authors:Parthier, C, Tittmann, K.
Deposit date:2010-04-23
Release date:2010-07-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The crystal structure of human transketolase and new insights into its mode of action.
J.Biol.Chem., 285, 2010
8W0V
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BU of 8w0v by Molmil
Crystal structure of broadly neutralizing antibody hcab55 in complex with Hepatitis C virus envelope glycoprotein E2 ectodomain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein E2, ...
Authors:Flyak, A.I, Wilcox, X.E.
Deposit date:2024-02-14
Release date:2024-03-27
Last modified:2024-04-17
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Convergent evolution and targeting of diverse E2 epitopes by human broadly neutralizing antibodies are associated with HCV clearance.
Immunity, 57, 2024
8U1L
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BU of 8u1l by Molmil
Cryo-EM structure of the RAF1-HSP90-CDC37 complex in the closed state
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein 83, Hsp90 co-chaperone Cdc37, ...
Authors:Finci, L.I, Simanshu, D.K.
Deposit date:2023-09-01
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural dynamics of RAF1-HSP90-CDC37 and HSP90 complexes reveal asymmetric client interactions and key structural elements.
Commun Biol, 7, 2024
3MI9
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BU of 3mi9 by Molmil
Crystal structure of HIV-1 Tat complexed with human P-TEFb
Descriptor: Cell division protein kinase 9, Cyclin-T1, Protein Tat, ...
Authors:Tahirov, T.H, Babayeva, N.D, Varzavand, K, Cooper, J.J, Sedore, S.C, Price, D.H.
Deposit date:2010-04-09
Release date:2010-06-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of HIV-1 Tat complexed with human P-TEFb.
Nature, 465, 2010
3MJL
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BU of 3mjl by Molmil
Crystal structure of human arginase I in complex with 2-aminoimidazole. Resolution 1.90 A.
Descriptor: 1H-imidazol-2-amine, Arginase-1, MANGANESE (II) ION
Authors:Di Costanzo, L, Christianson, D.W.
Deposit date:2010-04-13
Release date:2010-05-05
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of human arginase I in complex with 2-aminoimidazole. Resolution 1.90 A.
To be Published
8V8E
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BU of 8v8e by Molmil
Room-temperature X-ray structure of SARS-CoV-2 main protease catalytic domain (residues 1-199-6H) in complex with ensitrelvir (ESV)
Descriptor: 3C-like proteinase nsp5, 6-[(6-chloranyl-2-methyl-indazol-5-yl)amino]-3-[(1-methyl-1,2,4-triazol-3-yl)methyl]-1-[[2,4,5-tris(fluoranyl)phenyl]methyl]-1,3,5-triazine-2,4-dione, peptide
Authors:Kovalevsky, A, Coates, L.
Deposit date:2023-12-05
Release date:2024-05-29
Last modified:2024-06-12
Method:X-RAY DIFFRACTION (2 Å)
Cite:Visualizing the Active Site Oxyanion Loop Transition Upon Ensitrelvir Binding and Transient Dimerization of SARS-CoV-2 Main Protease.
J.Mol.Biol., 436, 2024
8V7W
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BU of 8v7w by Molmil
Room-temperature X-ray structure of SARS-CoV-2 main protease catalytic domain C145A precursor, residues nsp4(-6)-1-199-6H
Descriptor: Replicase polyprotein 1ab
Authors:Kovalevsky, A, Coates, L.
Deposit date:2023-12-04
Release date:2024-05-29
Last modified:2024-06-12
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Visualizing the Active Site Oxyanion Loop Transition Upon Ensitrelvir Binding and Transient Dimerization of SARS-CoV-2 Main Protease.
J.Mol.Biol., 436, 2024
9GPB
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BU of 9gpb by Molmil
THE ALLOSTERIC TRANSITION OF GLYCOGEN PHOSPHORYLASE
Descriptor: GLYCOGEN PHOSPHORYLASE B, PYRIDOXAL-5'-PHOSPHATE, SULFATE ION
Authors:Barford, D, Johnson, L.N.
Deposit date:1990-12-17
Release date:1992-10-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The allosteric transition of glycogen phosphorylase.
Nature, 340, 1989
2VV6
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BU of 2vv6 by Molmil
BJFIXLH IN FERRIC FORM
Descriptor: CHLORIDE ION, PROTOPORPHYRIN IX CONTAINING FE, SENSOR PROTEIN FIXL, ...
Authors:Ayers, R.A, Moffat, K.
Deposit date:2008-06-04
Release date:2008-11-04
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Changes in Quaternary Structure in the Signaling Mechanisms of Pas Domains.
Biochemistry, 47, 2008
3M7F
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BU of 3m7f by Molmil
Crystal structure of the Nedd4 C2/Grb10 SH2 complex
Descriptor: E3 ubiquitin-protein ligase NEDD4, Growth factor receptor-bound protein 10
Authors:Huang, Q, Szebenyi, M.
Deposit date:2010-03-16
Release date:2010-10-27
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Basis for the Interaction between the Growth Factor-binding Protein GRB10 and the E3 Ubiquitin Ligase NEDD4.
J.Biol.Chem., 285, 2010
3ME3
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BU of 3me3 by Molmil
Activator-Bound Structure of Human Pyruvate Kinase M2
Descriptor: 1,6-di-O-phosphono-beta-D-fructofuranose, 3-{[4-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-1,4-diazepan-1-yl]sulfonyl}aniline, Pyruvate kinase isozymes M1/M2, ...
Authors:Hong, B, Dimov, S, Tempel, W, Auld, D, Thomas, C, Boxer, M, Jianq, J.-K, Skoumbourdis, A, Min, S, Southall, N, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Inglese, J, Park, H, Structural Genomics Consortium (SGC)
Deposit date:2010-03-31
Release date:2010-04-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis.
Nat.Chem.Biol., 8, 2012
5A76
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BU of 5a76 by Molmil
KSHV LANA (ORF73) C-terminal domain, open non-ring conformation: orthorhombic crystal form
Descriptor: MAGNESIUM ION, ORF 73
Authors:Ponnusamy, R, Mcvey, C.E.
Deposit date:2015-07-02
Release date:2015-10-28
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Kshv But not Mhv-68 Lana Induces a Strong Bend Upon Binding to Terminal Repeat Viral DNA.
Nucleic Acids Res., 43, 2015
2VV8
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BU of 2vv8 by Molmil
Co-bound structure of bjFixLH
Descriptor: CARBON MONOXIDE, CHLORIDE ION, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Ayers, R.A, Moffat, K.
Deposit date:2008-06-04
Release date:2008-11-04
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Changes in Quaternary Structure in the Signaling Mechanisms of Pas Domains.
Biochemistry, 47, 2008
3MDU
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BU of 3mdu by Molmil
The structure of N-formimino-L-Glutamate Iminohydrolase from Pseudomonas aeruginosa complexed with N-Guanidino-L-Glutamate
Descriptor: GLYCEROL, N-carbamimidoyl-L-glutamic acid, N-formimino-L-Glutamate Iminohydrolase, ...
Authors:Fedorov, A.A, Fedorov, E.V, Marti-Arbona, R, Raushel, F.M, Almo, S.C.
Deposit date:2010-03-30
Release date:2011-03-09
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.4003 Å)
Cite:Structure of N-Formimino-l-glutamate Iminohydrolase from Pseudomonas aeruginosa.
Biochemistry, 54, 2015
3MIA
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BU of 3mia by Molmil
Crystal structure of HIV-1 Tat complexed with ATP-bound human P-TEFb
Descriptor: Cell division protein kinase 9, Cyclin-T1, MAGNESIUM ION, ...
Authors:Tahirov, T.H, Babayeva, N.D, Varzavand, K, Cooper, J.J, Sedore, S.C, Price, D.H.
Deposit date:2010-04-09
Release date:2010-06-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of HIV-1 Tat complexed with human P-TEFb.
Nature, 465, 2010
3MKH
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BU of 3mkh by Molmil
Podospora anserina Nitroalkane Oxidase
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, MAGNESIUM ION, NITROALKANE OXIDASE, ...
Authors:Tormos, J.R, Taylor, A.B, Daubner, S.C, Hart, P.J, Fitzpatrick, P.F.
Deposit date:2010-04-14
Release date:2010-06-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.995 Å)
Cite:Identification of a hypothetical protein from Podospora anserina as a nitroalkane oxidase.
Biochemistry, 49, 2010

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