3M7F
Crystal structure of the Nedd4 C2/Grb10 SH2 complex
Summary for 3M7F
| Entry DOI | 10.2210/pdb3m7f/pdb |
| Descriptor | Growth factor receptor-bound protein 10, E3 ubiquitin-protein ligase NEDD4 (3 entities in total) |
| Functional Keywords | nedd4, c2 domain, grb10, sh2 domain, phosphoprotein, ligase, ubl conjugation pathway, signaling protein-ligase complex, signaling protein/ligase |
| Biological source | Mus musculus (mouse) More |
| Cellular location | Cytoplasm: Q60760 P46935 |
| Total number of polymer chains | 2 |
| Total formula weight | 32983.81 |
| Authors | Huang, Q.,Szebenyi, M. (deposition date: 2010-03-16, release date: 2010-10-27, Last modification date: 2023-09-06) |
| Primary citation | Huang, Q.,Szebenyi, D.M. Structural Basis for the Interaction between the Growth Factor-binding Protein GRB10 and the E3 Ubiquitin Ligase NEDD4. J.Biol.Chem., 285:42130-42139, 2010 Cited by PubMed: 20980250DOI: 10.1074/jbc.M110.143412 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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