8V7W
Room-temperature X-ray structure of SARS-CoV-2 main protease catalytic domain C145A precursor, residues nsp4(-6)-1-199-6H
Summary for 8V7W
| Entry DOI | 10.2210/pdb8v7w/pdb |
| Related | 8V7T |
| Descriptor | Replicase polyprotein 1ab (2 entities in total) |
| Functional Keywords | viral protease, catalytic domain, cysteine protease, precursor, hydrolase |
| Biological source | Severe acute respiratory syndrome coronavirus 2 |
| Total number of polymer chains | 2 |
| Total formula weight | 47379.75 |
| Authors | Kovalevsky, A.,Coates, L. (deposition date: 2023-12-04, release date: 2024-05-29, Last modification date: 2024-06-12) |
| Primary citation | Kovalevsky, A.,Aniana, A.,Coates, L.,Ghirlando, R.,Nashed, N.T.,Louis, J.M. Visualizing the Active Site Oxyanion Loop Transition Upon Ensitrelvir Binding and Transient Dimerization of SARS-CoV-2 Main Protease. J.Mol.Biol., 436:168616-168616, 2024 Cited by PubMed: 38762033DOI: 10.1016/j.jmb.2024.168616 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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