8V7W
Room-temperature X-ray structure of SARS-CoV-2 main protease catalytic domain C145A precursor, residues nsp4(-6)-1-199-6H
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Replicase polyprotein 1ab | polymer | 215 | 23689.9 | 2 | UniProt (P0DTD1) Pfam (PF05409) In PDB | Severe acute respiratory syndrome coronavirus 2 | pp1ab,ORF1ab polyprotein |
2 | water | water | 18.0 | 130 | Chemie (HOH) |
Sequence modifications
A, B: -5 - 199 (UniProt: P0DTD1)
PDB | External Database | Details |
---|---|---|
Ser -7 | - | expression tag |
Gly -6 | - | expression tag |
Ala 145 | Cys 3408 | engineered mutation |
Leu 200 | - | expression tag |
Glu 201 | - | expression tag |
His 202 | - | expression tag |
His 203 | - | expression tag |
His 204 | - | expression tag |
His 205 | - | expression tag |
His 206 | - | expression tag |
His 207 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 47379.8 | |
All* | Total formula weight | 47379.8 |