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4DOZ
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BU of 4doz by Molmil
Crystal structure of Pyrococcus furiosus Cmr2 (Cas10)
Descriptor: Putative uncharacterized protein, ZINC ION
Authors:Zhu, X, Ye, K.
Deposit date:2012-02-12
Release date:2012-03-21
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal structure of Cmr2 suggests a nucleotide cyclase-related enzyme in type III CRISPR-Cas systems
Febs Lett., 586, 2012
5O9Z
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BU of 5o9z by Molmil
Cryo-EM structure of a pre-catalytic human spliceosome primed for activation (B complex)
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, Homo sapiens RNA, U6 small nuclear 1 (RNU6-1), ...
Authors:Bertram, K, Kastner, B.
Deposit date:2017-06-20
Release date:2017-08-16
Last modified:2018-10-24
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for Activation.
Cell, 170, 2017
6ZQD
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BU of 6zqd by Molmil
Cryo-EM structure of the 90S pre-ribosome from Saccharomyces cerevisiae, state Post-A1
Descriptor: 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ...
Authors:Cheng, J, Lau, B, Venuta, G.L, Berninghausen, O, Hurt, E, Beckmann, R.
Deposit date:2020-07-09
Release date:2020-09-23
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:90 S pre-ribosome transformation into the primordial 40 S subunit.
Science, 369, 2020
6ZQE
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BU of 6zqe by Molmil
Cryo-EM structure of the 90S pre-ribosome from Saccharomyces cerevisiae, state Dis-A (Poly-Ala)
Descriptor: 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ...
Authors:Cheng, J, Lau, B, Venuta, G.L, Berninghausen, O, Hurt, E, Beckmann, R.
Deposit date:2020-07-09
Release date:2020-09-23
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (7.1 Å)
Cite:90 S pre-ribosome transformation into the primordial 40 S subunit.
Science, 369, 2020
7O0G
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BU of 7o0g by Molmil
Structure of the foamy viral protease-reverse transcriptase in complex with RNA/DNA hybrid.
Descriptor: DNA (5'-D(*CP*CP*TP*CP*TP*CP*CP*TP*GP*GP*AP*CP*AP*AP*G)-3'), Pr125Pol, RNA (5'-R(*UP*UP*CP*UP*UP*GP*UP*CP*CP*AP*GP*GP*AP*GP*AP*GP*G)-3')
Authors:Nowak, E, Nowacka, M, Nowotny, M.
Deposit date:2021-03-26
Release date:2021-06-30
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structures of Substrate Complexes of Foamy Viral Protease-Reverse Transcriptase.
J.Virol., 95, 2021
5MQF
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BU of 5mqf by Molmil
Cryo-EM structure of a human spliceosome activated for step 2 of splicing (C* complex)
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, ATP-dependent RNA helicase DHX8, Cell division cycle 5-like protein, ...
Authors:Bertram, K, Hartmuth, K, Kastner, B.
Deposit date:2016-12-20
Release date:2017-03-22
Last modified:2018-11-21
Method:ELECTRON MICROSCOPY (5.9 Å)
Cite:Cryo-EM structure of a human spliceosome activated for step 2 of splicing.
Nature, 542, 2017
8FKY
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BU of 8fky by Molmil
Human nucleolar pre-60S ribosomal subunit (State F)
Descriptor: 28S rRNA, 5.8S rRNA, 60S ribosomal protein L10a, ...
Authors:Vanden Broeck, A, Klinge, S.
Deposit date:2022-12-21
Release date:2023-07-12
Last modified:2023-07-19
Method:ELECTRON MICROSCOPY (2.67 Å)
Cite:Principles of human pre-60 S biogenesis.
Science, 381, 2023
6ZMW
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BU of 6zmw by Molmil
Structure of a human 48S translational initiation complex
Descriptor: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
Authors:Brito Querido, J, Sokabe, M, Kraatz, S, Gordiyenko, Y, Skehel, M, Fraser, C, Ramakrishnan, V.
Deposit date:2020-07-04
Release date:2020-09-23
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structure of a human 48Stranslational initiation complex.
Science, 369, 2020
7A5P
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BU of 7a5p by Molmil
Human C Complex Spliceosome - Medium-resolution PERIPHERY
Descriptor: Cell division cycle 5-like protein, Crooked neck-like protein 1, Eukaryotic initiation factor 4A-III, ...
Authors:Bertram, K, Kastner, B.
Deposit date:2020-08-21
Release date:2020-10-14
Method:ELECTRON MICROSCOPY (5 Å)
Cite:Structural Insights into the Roles of Metazoan-Specific Splicing Factors in the Human Step 1 Spliceosome.
Mol.Cell, 80, 2020
5XJC
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BU of 5xjc by Molmil
Cryo-EM structure of the human spliceosome just prior to exon ligation at 3.6 angstrom
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Zhang, X, Yan, C, Hang, J, Finci, I.L, Lei, J, Shi, Y.
Deposit date:2017-04-30
Release date:2017-07-05
Last modified:2020-10-14
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:An Atomic Structure of the Human Spliceosome
Cell, 169, 2017
2KEQ
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BU of 2keq by Molmil
Solution structure of DnaE intein from Nostoc punctiforme
Descriptor: DNA polymerase III alpha subunit, Nucleic acid binding OB-fold tRNA/helicase-type
Authors:Oeemig, J.S, Aranko, A.S, Djupsj, J.B, Iwai, H.
Deposit date:2009-02-02
Release date:2009-05-19
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of DnaE intein from Nostoc punctiforme: structural basis for the design of a new split intein suitable for site-specific chemical modification.
Febs Lett., 583, 2009
8Q7N
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BU of 8q7n by Molmil
cryo-EM structure of the human spliceosomal B complex protomer (tri-snRNP core region)
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, MINX pre-mRNA, Microfibrillar-associated protein 1, ...
Authors:Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Urlaub, H, Stark, H, Luehrmann, R.
Deposit date:2023-08-16
Release date:2024-01-24
Last modified:2024-08-07
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Cryo-EM analyses of dimerized spliceosomes provide new insights into the functions of B complex proteins.
Embo J., 43, 2024
7D4I
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BU of 7d4i by Molmil
Cryo-EM structure of 90S small ribosomal precursors complex with the DEAH-box RNA helicase Dhr1 (State F)
Descriptor: 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ...
Authors:Du, Y, Zhang, J, An, W, Ye, K.
Deposit date:2020-09-24
Release date:2021-10-06
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Cryo-EM structure of 90S small ribosomal precursors complex with Dhr1
To Be Published
6FDP
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BU of 6fdp by Molmil
NMR structure of the second TPR domain of the human RPAP3 protein in complex with HSP90 peptide DTSRMEEVD
Descriptor: Heat shock protein HSP 90-alpha, RNA polymerase II-associated protein 3
Authors:Quinternet, M, Chagot, M.E, Manival, X.
Deposit date:2017-12-26
Release date:2018-08-01
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Deep Structural Analysis of RPAP3 and PIH1D1, Two Components of the HSP90 Co-chaperone R2TP Complex.
Structure, 26, 2018
6FDT
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BU of 6fdt by Molmil
NMR structure of the second TPR domain of the human RPAP3 protein in complex with HSP70 peptide SGPTIEEVD
Descriptor: Heat shock 70 kDa protein 1B, RNA polymerase II-associated protein 3
Authors:Quinternet, M, Chagot, M.E, Manival, X.
Deposit date:2017-12-26
Release date:2018-08-01
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Deep Structural Analysis of RPAP3 and PIH1D1, Two Components of the HSP90 Co-chaperone R2TP Complex.
Structure, 26, 2018
7QP6
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BU of 7qp6 by Molmil
Structure of the human 48S initiation complex in open state (h48S AUG open)
Descriptor: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
Authors:Yi, S.-H, Petrychenko, V, Schliep, J.E, Goyal, A, Linden, A, Chari, A, Urlaub, H, Stark, H, Rodnina, M.V, Adio, S, Fischer, N.
Deposit date:2022-01-03
Release date:2022-05-11
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Conformational rearrangements upon start codon recognition in human 48S translation initiation complex.
Nucleic Acids Res., 50, 2022
7QP7
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BU of 7qp7 by Molmil
Structure of the human 48S initiation complex in closed state (h48S AUG closed)
Descriptor: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
Authors:Yi, S.-H, Petrychenko, V, Schliep, J.E, Goyal, A, Linden, A, Chari, A, Urlaub, H, Stark, H, Rodnina, M.V, Adio, S, Fischer, N.
Deposit date:2022-01-03
Release date:2022-05-11
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Conformational rearrangements upon start codon recognition in human 48S translation initiation complex.
Nucleic Acids Res., 50, 2022
6IP8
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BU of 6ip8 by Molmil
Cryo-EM structure of the HCV IRES dependently initiated CMV-stalled 80S ribosome (Structure iv)
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Yokoyama, T, Shigematsu, H, Shirouzu, M, Imataka, H, Ito, T.
Deposit date:2018-11-02
Release date:2019-05-29
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:HCV IRES Captures an Actively Translating 80S Ribosome.
Mol.Cell, 74, 2019
6ND4
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BU of 6nd4 by Molmil
Conformational switches control early maturation of the eukaryotic small ribosomal subunit
Descriptor: 18S rRNA 5' domain start, 5'ETS rRNA, Bud21, ...
Authors:Hunziker, M, Barandun, J, Klinge, S.
Deposit date:2018-12-13
Release date:2019-06-19
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Conformational switches control early maturation of the eukaryotic small ribosomal subunit.
Elife, 8, 2019
6ZQF
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BU of 6zqf by Molmil
Cryo-EM structure of the 90S pre-ribosome from Saccharomyces cerevisiae, state Dis-B (Poly-Ala)
Descriptor: 18S rRNA, 40S ribosomal protein S1-A, 40S ribosomal protein S11-A, ...
Authors:Cheng, J, Lau, B, Venuta, G.L, Berninghausen, O, Hurt, E, Beckmann, R.
Deposit date:2020-07-09
Release date:2020-09-23
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (4.9 Å)
Cite:90 S pre-ribosome transformation into the primordial 40 S subunit.
Science, 369, 2020
6IP5
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BU of 6ip5 by Molmil
Cryo-EM structure of the CMV-stalled human 80S ribosome (Structure ii)
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Yokoyama, T, Shigematsu, H, Shirouzu, M, Imataka, H, Ito, T.
Deposit date:2018-11-02
Release date:2019-05-29
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:HCV IRES Captures an Actively Translating 80S Ribosome.
Mol.Cell, 74, 2019
6QDV
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BU of 6qdv by Molmil
Human post-catalytic P complex spliceosome
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ...
Authors:Fica, S.M, Oubridge, C, Wilkinson, M.E, Newman, A.J, Nagai, K.
Deposit date:2019-01-03
Release date:2019-02-20
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:A human postcatalytic spliceosome structure reveals essential roles of metazoan factors for exon ligation.
Science, 363, 2019
8F2I
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BU of 8f2i by Molmil
P53 monomer structure
Descriptor: Cellular tumor antigen p53
Authors:Solares, M, Kelly, D.F.
Deposit date:2022-11-08
Release date:2022-11-23
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (5 Å)
Cite:High-Resolution Imaging of Human Cancer Proteins Using Microprocessor Materials.
Chembiochem, 23, 2022
8F2H
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BU of 8f2h by Molmil
Wild type P53 dimer structure from human cancer cells
Descriptor: Cellular tumor antigen p53
Authors:Solares, M, Kelly, D.F.
Deposit date:2022-11-08
Release date:2022-11-23
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:High-Resolution Imaging of Human Cancer Proteins Using Microprocessor Materials.
Chembiochem, 23, 2022
6SGC
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BU of 6sgc by Molmil
Rabbit 80S ribosome stalled on a poly(A) tail
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ...
Authors:Chandrasekaran, V, Juszkiewicz, S, Choi, J, Puglisi, J.D, Brown, A, Shao, S, Ramakrishnan, V, Hegde, R.S.
Deposit date:2019-08-03
Release date:2019-12-04
Last modified:2022-03-30
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Mechanism of ribosome stalling during translation of a poly(A) tail.
Nat.Struct.Mol.Biol., 26, 2019

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