5O9Z

Cryo-EM structure of a pre-catalytic human spliceosome primed for activation (B complex)

Summary for 5O9Z

• Entry DOI: 10.2210/pdb5o9z/pdb
• EMDB information: 3766
• Descriptor: Pre-mRNA-processing-splicing factor 8, Thioredoxin-like protein 4A, Microfibrillar-associated protein 1, ... (43 entities in total)
• Functional Keywords: spliceosome, pre-mrna splicing, macromolecular complex, splicing
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 57
• Total formula weight: 2389149.82

Authors

Bertram, K.,Kastner, B. (deposition date: 2017-06-20, release date: 2017-08-16, Last modification date: 2018-10-24)

• Primary citation: Bertram, K.,Agafonov, D.E.,Dybkov, O.,Haselbach, D.,Leelaram, M.N.,Will, C.L.,Urlaub, H.,Kastner, B.,Luhrmann, R.,Stark, H.; Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for Activation.; Cell, 170:701-713.e11, 2017; PubMed: 28781166; DOI: 10.1016/j.cell.2017.07.011

Experimental method

ELECTRON MICROSCOPY (4.5 Å)