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2Q92
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BU of 2q92 by Molmil
E. coli methionine aminopeptidase Mn-form with inhibitor B23
Descriptor: 5-(2-NITROPHENYL)-2-FUROIC ACID, MANGANESE (II) ION, Methionine aminopeptidase, ...
Authors:Ye, Q.-Z.
Deposit date:2007-06-12
Release date:2008-01-01
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural analysis of inhibition of E. coli methionine aminopeptidase: implication of loop flexibility in selective inhibition of bacterial enzymes.
Bmc Struct.Biol., 7, 2007
2Q6M
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BU of 2q6m by Molmil
Catalytic fragment of Cholix toxin from Vibrio Cholerae in complex with the PJ34 inhibitor
Descriptor: Cholix toxin, N~2~,N~2~-DIMETHYL-N~1~-(6-OXO-5,6-DIHYDROPHENANTHRIDIN-2-YL)GLYCINAMIDE
Authors:Merrill, A.R, Jorgensen, R.
Deposit date:2007-06-05
Release date:2008-02-12
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Cholix Toxin, a Novel ADP-ribosylating Factor from Vibrio cholerae.
J.Biol.Chem., 283, 2008
3Q7V
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BU of 3q7v by Molmil
Beta-Lactam-Sensor Domain of BlaR1 (Apo) from Staphylococcus Aureus with Carboxylated Lys392
Descriptor: Beta-lactamase regulatory protein BlaR1, GLYCEROL, SULFATE ION
Authors:Borbulevych, O.Y, Mobashery, S, Baker, B.M.
Deposit date:2011-01-05
Release date:2011-06-29
Last modified:2013-01-09
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Lysine Nzeta-decarboxylation switch and activation of the beta-lactam sensor domain of BlaR1 protein of methicillin-resistant Staphylococcus aureus.
J.Biol.Chem., 286, 2011
4GHQ
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BU of 4ghq by Molmil
Crystal structure of EV71 3C proteinase
Descriptor: 3C proteinase
Authors:Chen, C, Wu, C, Cai, Q, Li, N, Peng, X, Cai, Y, Yin, K, Chen, X, Wang, X, Zhang, R, Liu, L, Chen, S, Li, J, Lin, T.
Deposit date:2012-08-08
Release date:2013-06-26
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structures of Enterovirus 71 3C proteinase (strain E2004104-TW-CDC) and its complex with rupintrivir
Acta Crystallogr.,Sect.D, 69, 2013
3QB1
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BU of 3qb1 by Molmil
Interleukin-2 mutant D10
Descriptor: Interleukin-2
Authors:Levin, A.M, Bates, D.L, Ring, A.M, Lin, J.T, Su, L, Krieg, C, Bowman, G.R, Novick, P, Pande, V.S, Khort, H.E, Boyman, O, Fathman, C.G, Garcia, K.C.
Deposit date:2011-01-12
Release date:2012-04-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Exploiting a natural conformational switch to engineer an interleukin-2 'superkine'
Nature, 484, 2012
2Q99
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BU of 2q99 by Molmil
Crystal Structure of Saccharopine Dehydrogenase from Saccharomyces cerevisiae
Descriptor: Saccharopine dehydrogenase [NAD+, L-lysine-forming
Authors:Berghuis, A.M, Burk, D.L.
Deposit date:2007-06-12
Release date:2007-11-06
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Structural Studies of the Final Enzyme in the alpha-Aminoadipate Pathway-Saccharopine Dehydrogenase from Saccharomyces cerevisiae
J.Mol.Biol., 373, 2007
3QCV
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BU of 3qcv by Molmil
Crystal structure of the LT3015 antibody Fab fragment in complex with lysophosphatidic acid (18:2)
Descriptor: (2R)-2-hydroxy-3-(phosphonooxy)propyl (9Z,12Z)-octadeca-9,12-dienoate, LT3015 antibody Fab fragment, heavy chain, ...
Authors:Fleming, J.K, Wojciak, J.M, Campbell, M.-A, Huxford, T.
Deposit date:2011-01-17
Release date:2011-03-30
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Biochemical and structural characterization of lysophosphatidic Acid binding by a humanized monoclonal antibody.
J.Mol.Biol., 408, 2011
3FMZ
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BU of 3fmz by Molmil
Crystal Structure of Retinol-Binding Protein 4 (RBP4) in complex with non-retinoid ligand
Descriptor: 2-[({4-[2-(trifluoromethyl)phenyl]piperidin-1-yl}carbonyl)amino]benzoic acid, Retinol-binding protein 4
Authors:Wang, Z, Johnstone, S, Walker, N.P.
Deposit date:2008-12-22
Release date:2009-01-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Identification and Characterization of a Non-retinoid Ligand for Retinol-binding Protein 4 Which Lowers Serum Retinol-binding Protein 4 Levels in Vivo.
J.Biol.Chem., 284, 2009
3QIW
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BU of 3qiw by Molmil
Crystal structure of the 226 TCR in complex with MCC-p5E/I-Ek
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, H-2 CLASS II HISTOCOMPATIBILITY ANTIGEN, E-K alpha chain, ...
Authors:Kruse, A.C, Ely, L.K, Newell, E.W, Davis, M.M, Garcia, K.C.
Deposit date:2011-01-27
Release date:2011-04-27
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural basis of specificity and cross-reactivity in T cell receptors specific for cytochrome c-I-E(k).
J.Immunol., 186, 2011
3QJ9
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BU of 3qj9 by Molmil
Crystal structure of fatty acid amide hydrolase with small molecule inhibitor
Descriptor: 1,2-ETHANEDIOL, 1-{(3S)-1-[4-(1-benzofuran-2-yl)pyrimidin-2-yl]piperidin-3-yl}-3-ethyl-1,3-dihydro-2H-benzimidazol-2-one, Fatty-acid amide hydrolase 1, ...
Authors:Min, X, Walker, N.P.C, Wang, Z.
Deposit date:2011-01-28
Release date:2011-04-27
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Discovery and molecular basis of potent noncovalent inhibitors of fatty acid amide hydrolase (FAAH).
Proc.Natl.Acad.Sci.USA, 108, 2011
3FJT
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BU of 3fjt by Molmil
Crystal structure of a human Fc fragment engineered for extended serum half-life
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-1 chain C region
Authors:Oganesyan, V, Wu, H, Dall'Acqua, W.F.
Deposit date:2008-12-15
Release date:2009-03-24
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural characterization of a human Fc fragment engineered for extended serum half-life.
Mol.Immunol., 46, 2009
3QJY
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BU of 3qjy by Molmil
Crystal structure of P-loop G234A mutant of subunit A of the A1AO ATP synthase
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETIC ACID, ...
Authors:Ragunathan, P, Manimekalai, M.S.S, Jeyakanthan, J, Gruber, G.
Deposit date:2011-01-31
Release date:2011-10-05
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Conserved glycine residues in the P-loop of ATP synthases form a doorframe for nucleotide entrance.
J.Mol.Biol., 413, 2011
3FP5
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BU of 3fp5 by Molmil
Crystal structure of ACBP from Moniliophthora perniciosa
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Acyl-CoA Binding Protein, ZINC ION
Authors:Monzani, P.S, Pereira, H.M, Melo, F.A, Meirelles, F.V, Oliva, G, Cascardo, J.C.M.
Deposit date:2009-01-04
Release date:2009-11-17
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:A new topology of ACBP from Moniliophthora perniciosa.
Biochim.Biophys.Acta, 1804, 2010
3QKQ
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BU of 3qkq by Molmil
Protein Tyrosine Phosphatase 1B - W179F mutant bound with vanadate
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, Tyrosine-protein phosphatase non-receptor type 1, ...
Authors:Brandao, T.A.S, Johnson, S.J, Hengge, A.C.
Deposit date:2011-02-01
Release date:2012-08-08
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The molecular details of WPD-loop movement differ in the protein-tyrosine phosphatases YopH and PTP1B.
Arch.Biochem.Biophys., 525, 2012
4FWO
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BU of 4fwo by Molmil
Crystal structure of Salmonella typhimurium propionate kinase (TdcD) in complex with GMP
Descriptor: 1,2-ETHANEDIOL, GUANOSINE-5'-MONOPHOSPHATE, Propionate kinase
Authors:Chittori, S, Savithri, H.S, Murthy, M.R.N.
Deposit date:2012-07-01
Release date:2013-06-19
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Mechanistic features of Salmonella typhimurium propionate kinase (TdcD): insights from kinetic and crystallographic studies.
Biochim.Biophys.Acta, 1834, 2013
3QH4
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BU of 3qh4 by Molmil
Crystal structure of esterase LipW from Mycobacterium marinum
Descriptor: Esterase LipW
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2011-01-25
Release date:2011-02-09
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural Basis for the Strict Substrate Selectivity of the Mycobacterial Hydrolase LipW.
Biochemistry, 95, 2016
3QHD
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BU of 3qhd by Molmil
Crystal structure of 2-C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATE Synthase from BURKHOLDERIA PSEUDOMALLEI bound to CYTIDINE, FOL795 and FOL955
Descriptor: 2-(pyridin-3-yl)-1,3-thiazole-4-carbaldehyde, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, 4-(1H-IMIDAZOL-1-YL)PHENOL, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2011-01-25
Release date:2011-02-09
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Leveraging structure determination with fragment screening for infectious disease drug targets: MECP synthase from Burkholderia pseudomallei.
J Struct Funct Genomics, 12, 2011
2QEC
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BU of 2qec by Molmil
Crystal structure of histone acetyltransferase HPA2 and related acetyltransferase (NP_600742.1) from Corynebacterium glutamicum ATCC 13032 at 1.90 A resolution
Descriptor: 1,2-ETHANEDIOL, Histone acetyltransferase HPA2 and related acetyltransferases
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2007-06-25
Release date:2007-07-10
Last modified:2023-01-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of histone acetyltransferase HPA2 and related acetyltransferase (NP_600742.1) from Corynebacterium glutamicum ATCC 13032 at 1.90 A resolution
To be published
2QEO
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BU of 2qeo by Molmil
Crystal Structure of Anopheles gambiae D7R4-norepinephrine complex
Descriptor: D7R4 Protein, L-NOREPINEPHRINE
Authors:Andersen, J.F, Mans, B.J, Calvo, E, Ribeiro, J.M.
Deposit date:2007-06-26
Release date:2007-10-09
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.315 Å)
Cite:The Crystal Structure of D7r4, a Salivary Biogenic Amine-binding Protein from the Malaria Mosquito Anopheles gambiae
J.Biol.Chem., 282, 2007
3FLU
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BU of 3flu by Molmil
Crystal structure of dihydrodipicolinate synthase from the pathogen Neisseria meningitidis
Descriptor: Dihydrodipicolinate synthase, GLYCEROL, SULFATE ION
Authors:Devenish, S.R.A, Hadfield, A.T.
Deposit date:2008-12-19
Release date:2009-06-23
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Cloning and characterisation of dihydrodipicolinate synthase from the pathogen Neisseria meningitidis.
Biochim.Biophys.Acta, 2009
4FZI
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BU of 4fzi by Molmil
Crystal structure of prostaglandin F synthase from Trypanosoma cruzi
Descriptor: GLUTAMIC ACID, Prostaglandin F synthase, SULFATE ION
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2012-07-06
Release date:2012-07-18
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structures of prostaglandin F synthase from the protozoa Leishmania major and Trypanosoma cruzi with NADP.
Acta Crystallogr F Struct Biol Commun, 71, 2015
3QJA
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BU of 3qja by Molmil
Crystal Structure of the Mycobacterium tuberculosis Indole-3-glycerol phosphate synthase (TrpC) in apo form
Descriptor: Indole-3-glycerol phosphate synthase, SULFATE ION
Authors:Reddy, M.C.M, Bruning, J.B, Thurman, C, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
Deposit date:2011-01-28
Release date:2011-06-15
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.29 Å)
Cite:Small-molecule scaffolds for Mycobacterium tuberculosis Indole Glycerol Phosphate Synthase (IGPS) inhibitors identified by high-throughput screening and defined by X-ray crystallography
To be Published
2QAZ
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BU of 2qaz by Molmil
Structure of C. crescentus SspB ortholog
Descriptor: SspB Protein
Authors:Chien, P, Grant, R.A, Sauer, R.T, Baker, T.A.
Deposit date:2007-06-15
Release date:2007-09-04
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of C. crescentus SspB ortholog
To be Published
3QNZ
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BU of 3qnz by Molmil
Orthorhombic form of IgG1 Fab fragment (in complex with antigenic tubulin peptide) sharing same Fv as IgA
Descriptor: Fab fragment of IMMUNOGLOBULIN G1 HEAVY CHAIN, Fab fragment of IMMUNOGLOBULIN G1 LIGHT CHAIN, GLYCEROL, ...
Authors:Trajtenberg, F, Correa, A, Buschiazzo, A.
Deposit date:2011-02-09
Release date:2012-02-15
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of a human IgA1 Fab fragment at 1.55 angstrom resolution: potential effect of the constant domains on antigen-affinity modulation
Acta Crystallogr.,Sect.D, 69, 2013
3QO6
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BU of 3qo6 by Molmil
Crystal structure analysis of the plant protease Deg1
Descriptor: Protease Do-like 1, chloroplastic, peptide
Authors:Clausen, T.
Deposit date:2011-02-09
Release date:2011-05-04
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural adaptation of the plant protease Deg1 to repair photosystem II during light exposure.
Nat.Struct.Mol.Biol., 18, 2011

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