6O2N
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5HYI
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![BU of 5hyi by Molmil](/molmil-images/mine/5hyi) | Glycosylated, disulfide-linked Hole-Hole Fc fragment | Descriptor: | Ig gamma-1 chain C region, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Kuglstatter, A, Stihle, M, Benz, J. | Deposit date: | 2016-02-01 | Release date: | 2017-02-01 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural differences between glycosylated, disulfide-linked heterodimeric Knob-into-Hole Fc fragment and its homodimeric Knob-Knob and Hole-Hole side products. Protein Eng. Des. Sel., 30, 2017
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7UWL
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![BU of 7uwl by Molmil](/molmil-images/mine/7uwl) | Structure of the IL-25-IL-17RB-IL-17RA ternary complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-17 receptor A, ... | Authors: | Wilson, S.C, Caveney, N.A, Jude, K.M, Garcia, K.C. | Deposit date: | 2022-05-03 | Release date: | 2022-07-27 | Last modified: | 2022-09-28 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Organizing structural principles of the IL-17 ligand-receptor axis. Nature, 609, 2022
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7UWM
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![BU of 7uwm by Molmil](/molmil-images/mine/7uwm) | Structure of the IL-17A-IL-17RA binary complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-17 receptor A, ... | Authors: | Wilson, S.C, Caveney, N.A, Jude, K.M, Garcia, K.C. | Deposit date: | 2022-05-03 | Release date: | 2022-07-27 | Last modified: | 2022-09-28 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Organizing structural principles of the IL-17 ligand-receptor axis. Nature, 609, 2022
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7UWK
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![BU of 7uwk by Molmil](/molmil-images/mine/7uwk) | Structure of the higher-order IL-25-IL-17RB complex | Descriptor: | Interleukin-17 receptor B, Interleukin-25 | Authors: | Wilson, S.C, Caveney, N.A, Jude, K.M, Garcia, K.C. | Deposit date: | 2022-05-03 | Release date: | 2022-07-27 | Last modified: | 2022-09-28 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Organizing structural principles of the IL-17 ligand-receptor axis. Nature, 609, 2022
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7UWJ
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![BU of 7uwj by Molmil](/molmil-images/mine/7uwj) | Structure of the homodimeric IL-25-IL-17RB binary complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-17 receptor B, Interleukin-25 | Authors: | Wilson, S.C, Caveney, N.A, Jude, K.M, Garcia, K.C. | Deposit date: | 2022-05-03 | Release date: | 2022-07-27 | Last modified: | 2022-09-28 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Organizing structural principles of the IL-17 ligand-receptor axis. Nature, 609, 2022
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6NWW
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6C63
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![BU of 6c63 by Molmil](/molmil-images/mine/6c63) | Crystal Structure of the Mango-II Fluorescent Aptamer Bound to TO1-Biotin | Descriptor: | 4-[(3-{2-[(2-methoxyethyl)amino]-2-oxoethyl}-1,3-benzothiazol-3-ium-2-yl)methyl]-1-methylquinolin-1-ium, POTASSIUM ION, RNA (32-MER), ... | Authors: | Trachman, R.J, Ferre-D'Amare, A.R. | Deposit date: | 2018-01-17 | Release date: | 2018-08-08 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.900028 Å) | Cite: | Crystal Structures of the Mango-II RNA Aptamer Reveal Heterogeneous Fluorophore Binding and Guide Engineering of Variants with Improved Selectivity and Brightness. Biochemistry, 57, 2018
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5XP0
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7UWN
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![BU of 7uwn by Molmil](/molmil-images/mine/7uwn) | Structure of the IL-17A-IL-17RA-IL-17RC ternary complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-17 receptor A, ... | Authors: | Wilson, S.C, Caveney, N.A, Jude, K.M, Garcia, K.C. | Deposit date: | 2022-05-03 | Release date: | 2022-07-27 | Last modified: | 2022-09-28 | Method: | ELECTRON MICROSCOPY (3.01 Å) | Cite: | Organizing structural principles of the IL-17 ligand-receptor axis. Nature, 609, 2022
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7DMU
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8JMR
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![BU of 8jmr by Molmil](/molmil-images/mine/8jmr) | Crystal structure of hinokiresinol synthase in complex with 1,7-bis(4-hydroxyphenyl)hepta-1,6-dien-3-one | Descriptor: | 1,7-bis(4-hydroxyphenyl)hepta-1,6-dien-3-one, Hinokiresinol synthase alpha subunit, Hinokiresinol synthase beta subunit, ... | Authors: | Ding, Y, Ushimaru, R, Mori, T, Abe, I. | Deposit date: | 2023-06-05 | Release date: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural and Mechanistic Insights into the C-C Bond-Forming Rearrangement Reaction Catalyzed by Heterodimeric Hinokiresinol Synthase. J.Am.Chem.Soc., 145, 2023
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8JMQ
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![BU of 8jmq by Molmil](/molmil-images/mine/8jmq) | Crystal structure of hinokiresinol synthase | Descriptor: | Hinokiresinol synthase alpha subunit, Hinokiresinol synthase beta subunit | Authors: | Ding, Y, Ushimaru, R, Mori, T, Abe, I. | Deposit date: | 2023-06-05 | Release date: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural and Mechanistic Insights into the C-C Bond-Forming Rearrangement Reaction Catalyzed by Heterodimeric Hinokiresinol Synthase. J.Am.Chem.Soc., 145, 2023
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6CQ6
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![BU of 6cq6 by Molmil](/molmil-images/mine/6cq6) | K2P2.1(TREK-1) apo structure | Descriptor: | CADMIUM ION, DECANE, POTASSIUM ION, ... | Authors: | Lolicato, M, Minor, D.L. | Deposit date: | 2018-03-14 | Release date: | 2018-03-28 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | K2P2.1 (TREK-1)-activator complexes reveal a cryptic selectivity filter binding site. Nature, 547, 2017
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2B00
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![BU of 2b00 by Molmil](/molmil-images/mine/2b00) | Crystal Structure of Porcine Pancreatic Phospholipase A2 in Complex with Glycocholate | Descriptor: | CALCIUM ION, GLYCOCHOLIC ACID, Phospholipase A2, ... | Authors: | Pan, Y.H, Bahnson, B.J, Jain, M.K. | Deposit date: | 2005-09-12 | Release date: | 2006-11-14 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structural basis for bile salt inhibition of pancreatic phospholipase A2. J.Mol.Biol., 369, 2007
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2B04
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![BU of 2b04 by Molmil](/molmil-images/mine/2b04) | Crystal Structure of Porcine Pancreatic Phospholipase A2 in Complex with Glycochenodeoxycholate | Descriptor: | CALCIUM ION, CHLORIDE ION, GLYCOCHENODEOXYCHOLIC ACID, ... | Authors: | Pan, Y.H, Bahnson, B.J, Jain, M.K. | Deposit date: | 2005-09-12 | Release date: | 2006-11-14 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis for bile salt inhibition of pancreatic phospholipase A2. J.Mol.Biol., 369, 2007
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7CY1
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![BU of 7cy1 by Molmil](/molmil-images/mine/7cy1) | Crystal Structure of MglC from Myxococcus xanthus | Descriptor: | Mutual gliding motility protein C, SODIUM ION | Authors: | Thakur, K.G, Kapoor, S, Kodesia, A. | Deposit date: | 2020-09-03 | Release date: | 2021-01-27 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.19 Å) | Cite: | Structural characterization of Myxococcus xanthus MglC, a component of the polarity control system, and its interactions with its paralog MglB. J.Biol.Chem., 2021
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5LSB
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![BU of 5lsb by Molmil](/molmil-images/mine/5lsb) | Crystal structure of yeast Hsh49p in complex with Cus1p binding domain. | Descriptor: | Cold sensitive U2 snRNA suppressor 1, Protein HSH49 | Authors: | van Roon, A.M, Obayashi, E, Sposito, B, Oubridge, C, Nagai, K. | Deposit date: | 2016-08-24 | Release date: | 2017-04-12 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of U2 snRNP SF3b components: Hsh49p in complex with Cus1p-binding domain. RNA, 23, 2017
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6NG0
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![BU of 6ng0 by Molmil](/molmil-images/mine/6ng0) | Crystal structure of HPK1 kinase domain T165E,S171E phosphomimetic mutant in complex with sunitinib in the inactive state. | Descriptor: | Mitogen-activated protein kinase kinase kinase kinase 1, N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carbo xamide | Authors: | Johnson, E, McTigue, M, Cronin, C.N. | Deposit date: | 2018-12-21 | Release date: | 2019-05-01 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Multiple conformational states of the HPK1 kinase domain in complex with sunitinib reveal the structural changes accompanying HPK1 trans-regulation. J.Biol.Chem., 294, 2019
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6CQ9
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![BU of 6cq9 by Molmil](/molmil-images/mine/6cq9) | K2P2.1(TREK-1):ML402 complex | Descriptor: | CADMIUM ION, HEXADECANE, N-((E,2S,3R)-1,3-DIHYDROXYOCTADEC-4-EN-2-YL)PALMITAMIDE, ... | Authors: | Lolicato, M, Minor, D.L. | Deposit date: | 2018-03-14 | Release date: | 2018-04-11 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | K2P2.1 (TREK-1)-activator complexes reveal a cryptic selectivity filter binding site. Nature, 547, 2017
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8J54
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![BU of 8j54 by Molmil](/molmil-images/mine/8j54) | Crystal structure of RXR/DR2 complex | Descriptor: | DNA (5'-D(*CP*AP*TP*GP*AP*CP*CP*TP*AP*CP*TP*GP*AP*CP*CP*TP*AP*G)-3'), DNA (5'-D(*CP*TP*AP*GP*GP*TP*CP*AP*GP*TP*AP*GP*GP*TP*CP*AP*TP*G)-3'), Retinoic acid receptor RXR, ... | Authors: | Chen, Y, Jiang, L. | Deposit date: | 2023-04-21 | Release date: | 2024-01-17 | Last modified: | 2024-04-17 | Method: | X-RAY DIFFRACTION (2.72 Å) | Cite: | Structural characterization of the DNA binding mechanism of retinoic acid-related orphan receptor gamma. Structure, 32, 2024
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5JW9
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5JZ7
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![BU of 5jz7 by Molmil](/molmil-images/mine/5jz7) | NGF IN COMPLEX WITH MEDI578 scFv | Descriptor: | Beta-nerve growth factor, MEDI578 scFv, heavy chain, ... | Authors: | Olsson, L.-L, Aagaard, A. | Deposit date: | 2016-05-16 | Release date: | 2017-01-11 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Engineering the surface properties of a human monoclonal antibody prevents self-association and rapid clearance in vivo. Sci Rep, 6, 2016
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6ZIQ
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![BU of 6ziq by Molmil](/molmil-images/mine/6ziq) | bovine ATP synthase stator domain, state 1 | Descriptor: | ATP synthase F(0) complex subunit B1, mitochondrial, ATP synthase F(0) complex subunit C1, ... | Authors: | Spikes, T.E, Montgomery, M.G, Walker, J.E. | Deposit date: | 2020-06-26 | Release date: | 2020-09-09 | Last modified: | 2020-09-30 | Method: | ELECTRON MICROSCOPY (4.33 Å) | Cite: | Structure of the dimeric ATP synthase from bovine mitochondria. Proc.Natl.Acad.Sci.USA, 117, 2020
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6TNG
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![BU of 6tng by Molmil](/molmil-images/mine/6tng) | Structure of FANCD2 in complex with FANCI | Descriptor: | Fanconi anemia complementation group I, Uncharacterized protein | Authors: | Alcon, P, Shakeel, S, Passmore, L.A. | Deposit date: | 2019-12-07 | Release date: | 2020-02-19 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | FANCD2-FANCI is a clamp stabilized on DNA by monoubiquitination of FANCD2 during DNA repair. Nat.Struct.Mol.Biol., 27, 2020
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