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7V0Y
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BU of 7v0y by Molmil
Local refinement of Band 3-III cytoplasmic domains, class 1 of erythrocyte ankyrin-1 complex
Descriptor: Band 3 anion transport protein
Authors:Vallese, F, Kim, K, Yen, L.Y, Johnston, J.D, Noble, A.J, Cali, T, Clarke, O.B.
Deposit date:2022-05-11
Release date:2022-07-20
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Architecture of the human erythrocyte ankyrin-1 complex.
Nat.Struct.Mol.Biol., 29, 2022
7V0S
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BU of 7v0s by Molmil
Local refinement of RhAG/CE trimer, class 1 of erythrocyte ankyrin-1 complex
Descriptor: Ammonium transporter Rh type A, Ankyrin-1, Blood group Rh(CE) polypeptide, ...
Authors:Vallese, F, Kim, K, Yen, L.Y, Johnston, J.D, Noble, A.J, Cali, T, Clarke, O.B.
Deposit date:2022-05-10
Release date:2022-07-20
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Architecture of the human erythrocyte ankyrin-1 complex.
Nat.Struct.Mol.Biol., 29, 2022
7V0X
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BU of 7v0x by Molmil
Local refinement of ankyrin-1 (C-terminal half), class 1 of erythrocyte ankyrin-1 complex
Descriptor: Ankyrin-1
Authors:Vallese, F, Kim, K, Yen, L.Y, Johnston, J.D, Noble, A.J, Cali, T, Clarke, O.B.
Deposit date:2022-05-11
Release date:2022-07-20
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Architecture of the human erythrocyte ankyrin-1 complex.
Nat.Struct.Mol.Biol., 29, 2022
7V0M
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BU of 7v0m by Molmil
Local refinement of ankyrin-1 (N-terminal half), class 1 of erythrocyte ankyrin-1 complex
Descriptor: Ankyrin-1, Band 3 anion transport protein
Authors:Vallese, F, Kim, K, Yen, L.Y, Johnston, J.D, Noble, A.J, Cali, T, Clarke, O.B.
Deposit date:2022-05-10
Release date:2022-07-20
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Architecture of the human erythrocyte ankyrin-1 complex.
Nat.Struct.Mol.Biol., 29, 2022
7V0K
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BU of 7v0k by Molmil
Consensus refinement of human erythrocyte ankyrin-1 complex (Composite map)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Ammonium transporter Rh type A, Ankyrin-1, ...
Authors:Vallese, F, Kim, K, Yen, L.Y, Johnston, J.D, Noble, A.J, Cali, T, Clarke, O.B.
Deposit date:2022-05-10
Release date:2022-07-20
Last modified:2022-07-27
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Architecture of the human erythrocyte ankyrin-1 complex.
Nat.Struct.Mol.Biol., 29, 2022
8JN8
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BU of 8jn8 by Molmil
Crystal structure of c-Src in complex with covalent inhibitor DC-Srci-6668
Descriptor: (2R)-N-cyclopentyl-2-[cyclopropyl(ethanoyl)amino]-2-(4-fluorophenyl)ethanamide, Proto-oncogene tyrosine-protein kinase Src
Authors:Zhang, H.M, Luo, C.
Deposit date:2023-06-06
Release date:2024-06-12
Method:X-RAY DIFFRACTION (1.902 Å)
Cite:The crystal structure of c-Src in complex with covalent inhibitor DC-Srci-6668
To Be Published
2MZN
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BU of 2mzn by Molmil
NMR structure of the HLTF HIRAN domain in its DNA-bound conformation
Descriptor: Helicase-like transcription factor
Authors:Korzhnev, D, Eldirany, S.
Deposit date:2015-02-18
Release date:2015-07-01
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:HLTF's Ancient HIRAN Domain Binds 3' DNA Ends to Drive Replication Fork Reversal.
Mol.Cell, 58, 2015
8JN9
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BU of 8jn9 by Molmil
Crystal structure of c-Src in complex with covalent inhibitor LW-Srci-8
Descriptor: N-[(1R)-1-[3,5-bis(fluoranyl)phenyl]-2-(cyclopentylamino)-2-oxidanylidene-ethyl]-N-cyclopropyl-prop-2-enamide, Proto-oncogene tyrosine-protein kinase Src
Authors:Zhang, H.M, Luo, C.
Deposit date:2023-06-06
Release date:2024-06-12
Method:X-RAY DIFFRACTION (2.724 Å)
Cite:The crystal structure of c-Src in complex with covalent inhibitor LW-Srci-8
To Be Published
6RPR
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BU of 6rpr by Molmil
LEM domain of Emerin mutant T43I in complex with BAF dimer and the Igfold of the lamin A/C
Descriptor: LEM domain of emerin mutant T43I, Prelamin-A/C, SULFATE ION, ...
Authors:Essawy, N, Samson, C.
Deposit date:2019-05-14
Release date:2020-03-04
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:An Emerin LEM-Domain Mutation Impairs Cell Response to Mechanical Stress.
Cells, 8, 2019
6PUO
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BU of 6puo by Molmil
Human TRPM2 in the apo state
Descriptor: Transient receptor potential cation channel subfamily M member 2
Authors:Du, J, Lu, W, Huang, Y.
Deposit date:2019-07-18
Release date:2019-09-25
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Ligand recognition and gating mechanism through three ligand-binding sites of human TRPM2 channel.
Elife, 8, 2019
7UX9
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BU of 7ux9 by Molmil
Arabidopsis DDM1 bound to nucleosome (H2A.W, H2B, H3.3, H4, with 147 bp DNA)
Descriptor: ATP-dependent DNA helicase DDM1, DNA (antisense strand), DNA (sense strand), ...
Authors:Ipsaro, J.J, Adams, D.W, Joshua-Tor, L.
Deposit date:2022-05-05
Release date:2023-08-09
Last modified:2023-09-27
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Chromatin remodeling of histone H3 variants by DDM1 underlies epigenetic inheritance of DNA methylation.
Cell, 186, 2023
6RA9
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BU of 6ra9 by Molmil
Novel structural features and post-translational modifications in eukaryotic elongation factor 1A2 from Oryctolagus cuniculus
Descriptor: Elongation factor 1-alpha 2, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Carriles, A.A, Hermoso, J, Gago, F.
Deposit date:2019-04-05
Release date:2020-06-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural Cues for Understanding eEF1A2 Moonlighting.
Chembiochem, 22, 2021
6ROI
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BU of 6roi by Molmil
Cryo-EM structure of the partially activated Drs2p-Cdc50p
Descriptor: (2R)-1-{[(R)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}-3-(octadecanoyloxy)propan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Timcenko, M, Lyons, J.A, Januliene, D, Ulstrup, J.J, Dieudonne, T, Montigny, C, Ash, M.R, Karlsen, J.L, Boesen, T, Kuhlbrandt, W, Lenoir, G, Moeller, A, Nissen, P.
Deposit date:2019-05-13
Release date:2019-07-03
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structure and autoregulation of a P4-ATPase lipid flippase.
Nature, 571, 2019
8KCB
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BU of 8kcb by Molmil
Complex of DDM1-nucleosome(H2A) complex with DDM1 bound to SHL2
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent DNA helicase DDM1, BERYLLIUM TRIFLUORIDE ION, ...
Authors:Zhang, H, Zhang, Y.
Deposit date:2023-08-07
Release date:2024-06-26
Method:ELECTRON MICROSCOPY (3.17 Å)
Cite:Mechanism of heterochromatin remodeling revealed by the DDM1 bound nucleosome structures.
Structure, 2024
8KCC
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BU of 8kcc by Molmil
Complex of DDM1-nucleosome(H2A.W) complex with DDM1 bound to SHL2
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent DNA helicase DDM1, BERYLLIUM TRIFLUORIDE ION, ...
Authors:Zhang, H, Zhang, Y.
Deposit date:2023-08-07
Release date:2024-06-26
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Mechanism of heterochromatin remodeling revealed by the DDM1 bound nucleosome structures.
Structure, 2024
7TM3
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BU of 7tm3 by Molmil
Structure of the rabbit 80S ribosome stalled on a 2-TMD Rhodopsin intermediate in complex with the multipass translocon
Descriptor: 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Kim, M.K, Lewis, A.J.O, Keenan, R.J, Hegde, R.S.
Deposit date:2022-01-19
Release date:2022-10-19
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.25 Å)
Cite:Mechanism of an intramembrane chaperone for multipass membrane proteins.
Nature, 611, 2022
7TUT
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BU of 7tut by Molmil
Structure of the rabbit 80S ribosome stalled on a 4-TMD Rhodopsin intermediate in complex with the multipass translocon
Descriptor: 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Kim, M.K, Lewis, A.J.O, Keenan, R.J, Hegde, R.S.
Deposit date:2022-02-03
Release date:2022-10-19
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.88 Å)
Cite:Mechanism of an intramembrane chaperone for multipass membrane proteins.
Nature, 611, 2022
6ROH
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BU of 6roh by Molmil
Cryo-EM structure of the autoinhibited Drs2p-Cdc50p
Descriptor: 1,2-DICAPROYL-SN-PHOSPHATIDYL-L-SERINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Timcenko, M, Lyons, J.A, Januliene, D, Ulstrup, J.J, Dieudonne, T, Montigny, C, Ash, M.R, Karlsen, J.L, Boesen, T, Kuhlbrandt, W, Lenoir, G, Moeller, A, Nissen, P.
Deposit date:2019-05-13
Release date:2019-07-03
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structure and autoregulation of a P4-ATPase lipid flippase.
Nature, 571, 2019
7VDT
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BU of 7vdt by Molmil
The motor-nucleosome module of human chromatin remodeling PBAF-nucleosome complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA (207-MER), ...
Authors:Chen, Z.C, Chen, K.J, Yuan, J.J.
Deposit date:2021-09-07
Release date:2022-05-18
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structure of human chromatin-remodelling PBAF complex bound to a nucleosome.
Nature, 605, 2022
2OYC
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BU of 2oyc by Molmil
Crystal structure of human pyridoxal phosphate phosphatase
Descriptor: Pyridoxal phosphate phosphatase, SODIUM ION, TUNGSTATE(VI)ION
Authors:Ramagopal, U.A, Freeman, J, Izuka, M, Toro, R, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2007-02-21
Release date:2007-03-13
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Structural genomics of protein phosphatases.
J.Struct.Funct.Genom., 8, 2007
6ROJ
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BU of 6roj by Molmil
Cryo-EM structure of the activated Drs2p-Cdc50p
Descriptor: (2R)-1-{[(R)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}-3-(octadecanoyloxy)propan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cell division control protein 50, ...
Authors:Timcenko, M, Lyons, J.A, Januliene, D, Ulstrup, J.J, Dieudonne, T, Montigny, C, Ash, M.R, Karlsen, J.L, Boesen, T, Kuhlbrandt, W, Lenoir, G, Moeller, A, Nissen, P.
Deposit date:2019-05-13
Release date:2019-07-03
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structure and autoregulation of a P4-ATPase lipid flippase.
Nature, 571, 2019
2P69
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BU of 2p69 by Molmil
Crystal Structure of Human Pyridoxal Phosphate Phosphatase with PLP
Descriptor: CALCIUM ION, PYRIDOXAL-5'-PHOSPHATE, Pyridoxal phosphate phosphatase
Authors:Ramagopal, U.A, Freeman, J, Izuka, M, Toro, R, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2007-03-16
Release date:2007-04-03
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural genomics of protein phosphatases.
J.Struct.Funct.Genom., 8, 2007
2ETR
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BU of 2etr by Molmil
Crystal Structure of ROCK I bound to Y-27632
Descriptor: (R)-TRANS-4-(1-AMINOETHYL)-N-(4-PYRIDYL) CYCLOHEXANECARBOXAMIDE, Rho-associated protein kinase 1
Authors:Jacobs, M.
Deposit date:2005-10-27
Release date:2005-11-08
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The Structure of Dimeric ROCK I Reveals the Mechanism for Ligand Selectivity.
J.Biol.Chem., 281, 2006
2ERZ
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BU of 2erz by Molmil
Crystal Structure of c-AMP Dependent Kinase (PKA) bound to hydroxyfasudil
Descriptor: 1-(1-HYDROXY-5-ISOQUINOLINESULFONYL)HOMOPIPERAZINE, cAMP-dependent protein kinase inhibitor, alpha form, ...
Authors:Jacobs, M.
Deposit date:2005-10-25
Release date:2005-11-08
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The Structure of Dimeric ROCK I Reveals the Mechanism for Ligand Selectivity.
J.Biol.Chem., 281, 2006
2P27
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BU of 2p27 by Molmil
Crystal Structure of Human Pyridoxal Phosphate Phosphatase with Mg2+ at 1.9 A resolution
Descriptor: MAGNESIUM ION, Pyridoxal phosphate phosphatase
Authors:Ramagopal, U.A, Freeman, J, Izuka, M, Toro, R, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2007-03-07
Release date:2007-03-13
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural genomics of protein phosphatases.
J.Struct.Funct.Genom., 8, 2007

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