8JN8

Crystal structure of c-Src in complex with covalent inhibitor DC-Srci-6668

Summary for 8JN8

• Entry DOI: 10.2210/pdb8jn8/pdb
• Descriptor: Proto-oncogene tyrosine-protein kinase Src, (2R)-N-cyclopentyl-2-[cyclopropyl(ethanoyl)amino]-2-(4-fluorophenyl)ethanamide (3 entities in total)
• Functional Keywords: src kinase, covalent inhibitor, auto-phosphorylation site, oncoprotein, oncoprotein-inhibitor complex, oncoprotein/inhibitor
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 60304.94

Authors

Zhang, H.M.,Luo, C. (deposition date: 2023-06-06, release date: 2024-06-12, Last modification date: 2024-11-13)

• Primary citation: Zhang, H.M.,Luo, C.; The crystal structure of c-Src in complex with covalent inhibitor DC-Srci-6668; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.902 Å)