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8JN8

Crystal structure of c-Src in complex with covalent inhibitor DC-Srci-6668

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Proto-oncogene tyrosine-protein kinase Srcpolymer53659986.61UniProt (P12931)
Pfam (PF00018)
Pfam (PF00017)
Pfam (PF07714)
Homo sapiens (human)Proto-oncogene c-Src,pp60c-src,p60-Src
2B
(A)
(2R)-N-cyclopentyl-2-[cyclopropyl(ethanoyl)amino]-2-(4-fluorophenyl)ethanamidenon-polymer318.41Chemie (JA6)
3C
(A)
waterwater18.0337Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight59986.6
Non-Polymers*Number of molecules1
Total formula weight318.4
All*Total formula weight60304.9
*Water molecules are not included.

247947

PDB entries from 2026-01-21

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