6ROJ

Cryo-EM structure of the activated Drs2p-Cdc50p

Summary for 6ROJ

EMDB information4974
DescriptorProbable phospholipid-transporting ATPase DRS2,Oxaloacetate decarboxylase alpha chain, Cell division control protein 50, MAGNESIUM ION, ... (7 entities in total)
Functional Keywordslipid flippase, lipid transport, p-type atpase, ps transport.
Biological sourceSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
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Total number of polymer chains2
Total molecular weight214651.44
Authors
Timcenko, M.,Lyons, J.A.,Januliene, D.,Ulstrup, J.J.,Dieudonne, T.,Montigny, C.,Ash, M.R.,Karlsen, J.L.,Boesen, T.,Kuhlbrandt, W.,Lenoir, G.,Moeller, A.,Nissen, P. (deposition date: 2019-05-13, release date: 2019-07-03, Last modification date: 2019-12-18)
Primary citation
Timcenko, M.,Lyons, J.A.,Januliene, D.,Ulstrup, J.J.,Dieudonne, T.,Montigny, C.,Ash, M.R.,Karlsen, J.L.,Boesen, T.,Kuhlbrandt, W.,Lenoir, G.,Moeller, A.,Nissen, P.
Structure and autoregulation of a P4-ATPase lipid flippase.
Nature, 571:366-370, 2019
PubMed: 31243363 (PDB entries with the same primary citation)
DOI: 10.1038/s41586-019-1344-7
MImport into Mendeley
Experimental method
ELECTRON MICROSCOPY
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Structure validation

ClashscoreRamachandran outliersSidechain outliers30 0.5%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures
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