6RPR

LEM domain of Emerin mutant T43I in complex with BAF dimer and the Igfold of the lamin A/C

Summary for 6RPR

Entry DOI	10.2210/pdb6rpr/pdb
Descriptor	Prelamin-A/C, barrier to autointegration factor (BAF), LEM domain of emerin mutant T43I, ... (5 entities in total)
Functional Keywords	nuclear membrane protein, dna binding protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	37782.51
Authors	Essawy, N.,Samson, C. (deposition date: 2019-05-14, release date: 2020-03-04, Last modification date: 2024-01-24)
Primary citation	Essawy, N.,Samson, C.,Petitalot, A.,Moog, S.,Bigot, A.,Herrada, I.,Marcelot, A.,Arteni, A.A.,Coirault, C.,Zinn-Justin, S. An Emerin LEM-Domain Mutation Impairs Cell Response to Mechanical Stress. Cells, 8:-, 2019 Cited by PubMed: 31185657 DOI: 10.3390/cells8060570 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.26 Å)

Structure validation