PDB: 52540 resultsInfo pagesStatus searchChemie searchBIRD

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7DE8	Crystal Structure of outer membrane protein PorB with G103K mutations from Neisseria meningitidis W135 Descriptor: Outer membrane protein Authors: Tanabe, M, Kattner, C. Deposit date: 2020-11-02 Release date: 2021-03-31 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.76 Å) Cite: An antibiotic-resistance conferring mutation in a neisserial porin: Structure, ion flux, and ampicillin binding. Biochim Biophys Acta Biomembr, 1863, 2021
6TQL	Cryo-EM of elastase-treated human uromodulin (UMOD)/Tamm-Horsfall protein (THP) filament Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Stsiapanava, A, Xu, C, Carroni, M, Wu, B, Jovine, L. Deposit date: 2019-12-16 Release date: 2020-11-04 Last modified: 2021-03-03 Method: ELECTRON MICROSCOPY (3.96 Å) Cite: Cryo-EM structure of native human uromodulin, a zona pellucida module polymer. Embo J., 39, 2020
6TQK	Cryo-EM of native human uromodulin (UMOD)/Tamm-Horsfall protein (THP) filament. Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Uromodulin, ... Authors: Stsiapanava, A, Xu, C, Carroni, M, Wu, B, Jovine, L. Deposit date: 2019-12-16 Release date: 2020-11-04 Last modified: 2021-03-03 Method: ELECTRON MICROSCOPY (3.35 Å) Cite: Cryo-EM structure of native human uromodulin, a zona pellucida module polymer. Embo J., 39, 2020
7RGF	Protocadherin gammaC4 EC1-4 crystal structure disrupted trans interface Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... Authors: Goodman, K.M, Mannepalli, S, Honig, B, Shapiro, L. Deposit date: 2021-07-15 Release date: 2022-03-16 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.4 Å) Cite: How clustered protocadherin binding specificity is tuned for neuronal self-/nonself-recognition. Elife, 11, 2022
7NMN	Rabbit HCN4 stabilised in amphipol A8-35 Descriptor: Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4,Rabbit HCN4 Authors: Chaves-Sanjuan, A. Deposit date: 2021-02-23 Release date: 2021-06-30 Last modified: 2024-07-10 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Gating movements and ion permeation in HCN4 pacemaker channels. Mol.Cell, 81, 2021
8SUJ	Joint X-ray/neutron structure of Thermus thermophilus serine hydroxymethyltransferase (TthSHMT) in internal aldimine state Descriptor: SULFATE ION, Serine hydroxymethyltransferase Authors: Drago, V.N, Kovalevsky, A. Deposit date: 2023-05-12 Release date: 2023-08-16 Last modified: 2023-11-15 Method: NEUTRON DIFFRACTION (2.3 Å), X-RAY DIFFRACTION Cite: Revealing protonation states and tracking substrate in serine hydroxymethyltransferase with room-temperature X-ray and neutron crystallography. Commun Chem, 6, 2023
8SSJ	Room-temperature X-ray structure of human mitochondrial serine hydroxymethyltransferase (hSHMT2) Descriptor: CHLORIDE ION, Serine hydroxymethyltransferase, mitochondrial Authors: Drago, V.N, Kovalevsky, A. Deposit date: 2023-05-08 Release date: 2023-08-16 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Revealing protonation states and tracking substrate in serine hydroxymethyltransferase with room-temperature X-ray and neutron crystallography. Commun Chem, 6, 2023
8SUI	Joint X-ray/neutron structure of Thermus thermophilus serine hydroxymethyltransferase (TthSHMT) in internal aldimine state with L-Ser bound in a pre-Michalis complex Descriptor: SERINE, SULFATE ION, Serine hydroxymethyltransferase Authors: Drago, V.N, Kovalevsky, A. Deposit date: 2023-05-12 Release date: 2023-08-16 Last modified: 2023-11-15 Method: NEUTRON DIFFRACTION (2.3 Å), X-RAY DIFFRACTION Cite: Revealing protonation states and tracking substrate in serine hydroxymethyltransferase with room-temperature X-ray and neutron crystallography. Commun Chem, 6, 2023
8SSY	Room-temperature X-ray structure of Thermus thermophilus serine hydroxymethyltransferase (SHMT) bound with D-Ser in a pseudo-Michaelis complex Descriptor: D-SERINE, SULFATE ION, Serine hydroxymethyltransferase Authors: Drago, V.N, Kovalevsky, A. Deposit date: 2023-05-09 Release date: 2023-08-16 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Revealing protonation states and tracking substrate in serine hydroxymethyltransferase with room-temperature X-ray and neutron crystallography. Commun Chem, 6, 2023
8SJ7	Crystal structure of FBF-2 (RBD+CT) in complex with compact FBE RNA Descriptor: Fem-3 mRNA-binding factor 2, RNA (5'-R(*CP*UP*GP*UP*GP*AP*AP*UP*G)-3') Authors: Qiu, C, Hall, T.M.T. Deposit date: 2023-04-17 Release date: 2023-09-27 Last modified: 2024-04-10 Method: X-RAY DIFFRACTION (2.09 Å) Cite: Intra- and inter-molecular regulation by intrinsically-disordered regions governs PUF protein RNA binding. Nat Commun, 14, 2023
7RGX	Crystal structure of human galectin-3 CRD in complex with Methyl 2-O-(2-nitrobenzoyl)-3-O-(4-methylbenzoyl)-b-D-talopyranoside Descriptor: CHLORIDE ION, Galectin-3, methyl 3-O-(4-methylbenzoyl)-2-O-(2-nitrobenzoyl)-beta-D-talopyranoside Authors: Bum-Erdene, K, Kishor, C, Blanchard, H. Deposit date: 2021-07-15 Release date: 2022-07-13 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.58 Å) Cite: Novel Selective Galectin-3 Antagonists Are Cytotoxic to Acute Lymphoblastic Leukemia. J.Med.Chem., 65, 2022
7RGY	Crystal structure of human galectin-3 CRD in complex with Methyl 2-O-(2-nitro-4-chloro)-benzoyl-3-O-toluoyl-b-D-talopyranoside Descriptor: CHLORIDE ION, Galectin-3, methyl 2-O-(4-chloro-2-nitrobenzoyl)-3-O-(4-methylbenzoyl)-beta-D-talopyranoside Authors: Collins, P.M, Kishor, C, Blanchard, H. Deposit date: 2021-07-15 Release date: 2022-07-13 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.337 Å) Cite: Novel Selective Galectin-3 Antagonists Are Cytotoxic to Acute Lymphoblastic Leukemia. J.Med.Chem., 65, 2022
7RH0	Crystal structure of human galectin-3 CRD in complex with Methyl 2-O-(2-nitro-4-trifluoromethyl-benzoyl)-3-O-toluoyl-b-D-talopyranoside Descriptor: CHLORIDE ION, Galectin-3, methyl 3-O-(4-methylbenzoyl)-2-O-[2-nitro-4-(trifluoromethyl)benzoyl]-beta-D-talopyranoside Authors: Collins, P.M, Kishor, C, Blanchard, H. Deposit date: 2021-07-16 Release date: 2022-07-13 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.487 Å) Cite: Novel Selective Galectin-3 Antagonists Are Cytotoxic to Acute Lymphoblastic Leukemia. J.Med.Chem., 65, 2022
7RH1	Crystal structure of human galectin-3 CRD in complex with Methyl 2-O-(3-nitro-benzoyl)-3-toluoyl-b-D-talopyranoside Descriptor: CHLORIDE ION, Galectin-3, methyl 3-O-(4-methylbenzoyl)-2-O-(3-nitrobenzoyl)-beta-D-talopyranoside Authors: Collins, P.M, Kishor, C, Blanchard, H. Deposit date: 2021-07-16 Release date: 2022-07-13 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.444 Å) Cite: Novel Selective Galectin-3 Antagonists Are Cytotoxic to Acute Lymphoblastic Leukemia. J.Med.Chem., 65, 2022
7RGZ	Crystal structure of human galectin-3 CRD in complex with Methyl 2-O-(2-nitro-4-fluoro)-benzoyl-3-O-toluoyl-b-D-talopyranoside Descriptor: CHLORIDE ION, Galectin-3, methyl 2-O-(4-fluoro-2-nitrobenzoyl)-3-O-(4-methylbenzoyl)-beta-D-talopyranoside Authors: Collins, P.M, Kishor, C, Blanchard, H. Deposit date: 2021-07-16 Release date: 2022-07-13 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.485 Å) Cite: Novel Selective Galectin-3 Antagonists Are Cytotoxic to Acute Lymphoblastic Leukemia. J.Med.Chem., 65, 2022
7RH3	Co-crystallization of human galectin-3 CRD complex with Methyl 2-O-(2-nitro-4-chloro)-benzoyl-3-O-toluoyl-b-D-talopyranoside Descriptor: CHLORIDE ION, Galectin-3, methyl 2-O-(4-chloro-2-nitrobenzoyl)-3-O-(4-methylbenzoyl)-beta-D-talopyranoside Authors: Collins, P.M, Kishor, C, Blanchard, H. Deposit date: 2021-07-16 Release date: 2022-07-13 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.05 Å) Cite: Novel Selective Galectin-3 Antagonists Are Cytotoxic to Acute Lymphoblastic Leukemia. J.Med.Chem., 65, 2022
7RH4	Co-crystallization of human galectin-3 CRD complex with Methyl 2-O-(2-nitro-4-fluoro)-benzoyl-3-O-toluoyl-b-D-talopyranoside Descriptor: CHLORIDE ION, Galectin-3, methyl 2-O-(4-fluoro-2-nitrobenzoyl)-3-O-(4-methylbenzoyl)-beta-D-talopyranoside Authors: Collins, P.M, Kishor, C, Blanchard, H. Deposit date: 2021-07-16 Release date: 2022-07-13 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.201 Å) Cite: Novel Selective Galectin-3 Antagonists Are Cytotoxic to Acute Lymphoblastic Leukemia. J.Med.Chem., 65, 2022
7QZR	Structure of native leukocyte myeloperoxidase in complex with the Staphyloccal Peroxidase Inhibitor SPIN from Staphylococcus aureus Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... Authors: Pfanzagl, V, Brito, J.A. Deposit date: 2022-01-31 Release date: 2022-10-26 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.18 Å) Cite: The staphylococcal inhibitory protein SPIN binds to human myeloperoxidase with picomolar affinity but only dampens halide oxidation. J.Biol.Chem., 298, 2022
7R0L	Structure of the FK1 domain of the FKBP51 G64S variant in complex with SAFit1 Descriptor: 2-[3-[(1~{R})-1-[(2~{S})-1-[(2~{S})-2-cyclohexyl-2-(3,4,5-trimethoxyphenyl)ethanoyl]piperidin-2-yl]carbonyloxy-3-(3,4-dimethoxyphenyl)propyl]phenoxy]ethanoic acid, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, ... Authors: Meyners, C, Hausch, F. Deposit date: 2022-02-02 Release date: 2022-11-16 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.1 Å) Cite: Binding pocket stabilization by high-throughput screening of yeast display libraries. Front Mol Biosci, 9, 2022
7S02	Crystal structure of FBF-2 in complex with LST-1 site A peptide and FBE RNA Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, FBE RNA, ... Authors: Qiu, C, Hall, T.M.T. Deposit date: 2021-08-28 Release date: 2021-12-29 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.34 Å) Cite: Bipartite interaction sites differentially modulate RNA-binding affinity of a protein complex essential for germline stem cell self-renewal. Nucleic Acids Res., 50, 2022
7TZF	Human Amylin3 Receptor in complex with Gs and rat amylin peptide Descriptor: (2S)-2-{[(1R)-1-hydroxyhexadecyl]oxy}-3-{[(1R)-1-hydroxyoctadecyl]oxy}propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ... Authors: Cao, J, Belousoff, M.J, Johnson, R.M, Wootten, D.L, Sexton, P.M. Deposit date: 2022-02-15 Release date: 2022-03-23 Last modified: 2022-04-06 Method: ELECTRON MICROSCOPY (2.4 Å) Cite: A structural basis for amylin receptor phenotype. Science, 375, 2022
7TYH	Human Amylin2 Receptor in complex with Gs and human calcitonin peptide Descriptor: Calcitonin, Calcitonin receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... Authors: Cao, J, Belousoff, M.J, Johnson, R.M, Wootten, D.L, Sexton, P.M. Deposit date: 2022-02-13 Release date: 2022-03-23 Last modified: 2022-04-06 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: A structural basis for amylin receptor phenotype. Science, 375, 2022
7TYY	Human Amylin2 Receptor in complex with Gs and salmon calcitonin peptide Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, Calcitonin receptor, ... Authors: Cao, J, Belousoff, M.J, Johnson, R.M, Wootten, D.L, Sexton, P.M. Deposit date: 2022-02-14 Release date: 2022-03-23 Last modified: 2022-04-06 Method: ELECTRON MICROSCOPY (3 Å) Cite: A structural basis for amylin receptor phenotype. Science, 375, 2022
7TYF	Human Amylin1 Receptor in complex with Gs and rat amylin peptide Descriptor: (2S)-2-{[(1R)-1-hydroxyhexadecyl]oxy}-3-{[(1R)-1-hydroxyoctadecyl]oxy}propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ... Authors: Cao, J, Belousoff, M.J, Johnson, R.M, Wootten, D.L, Sexton, P.M. Deposit date: 2022-02-13 Release date: 2022-03-23 Last modified: 2022-04-06 Method: ELECTRON MICROSCOPY (2.2 Å) Cite: A structural basis for amylin receptor phenotype. Science, 375, 2022
7TYW	Human Amylin1 Receptor in complex with Gs and salmon calcitonin peptide Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, Calcitonin receptor, ... Authors: Cao, J, Belousoff, M.J, Johnson, R.M, Wootten, D.L, Sexton, P.M. Deposit date: 2022-02-14 Release date: 2022-03-23 Last modified: 2022-04-06 Method: ELECTRON MICROSCOPY (3 Å) Cite: A structural basis for amylin receptor phenotype. Science, 375, 2022

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