7QZR

Structure of native leukocyte myeloperoxidase in complex with the Staphyloccal Peroxidase Inhibitor SPIN from Staphylococcus aureus

Summary for 7QZR

Entry DOI	10.2210/pdb7qzr/pdb
Descriptor	Myeloperoxidase light chain, CALCIUM ION, PHOSPHATE ION, ... (13 entities in total)
Functional Keywords	phagocytosis innate immune response inhibitor complex, oxidoreductase
Biological source	Staphylococcus aureus More
Total number of polymer chains	6
Total formula weight	160750.10
Authors	Pfanzagl, V.,Brito, J.A. (deposition date: 2022-01-31, release date: 2022-10-26, Last modification date: 2024-01-31)
Primary citation	Leitgeb, U.,Furtmuller, P.G.,Hofbauer, S.,Brito, J.A.,Obinger, C.,Pfanzagl, V. The staphylococcal inhibitory protein SPIN binds to human myeloperoxidase with picomolar affinity but only dampens halide oxidation. J.Biol.Chem., 298:102514-102514, 2022 Cited by PubMed: 36150500 DOI: 10.1016/j.jbc.2022.102514 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.18 Å)

Structure validation