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3P10
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BU of 3p10 by Molmil
Crystal structure of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase from Burkholderia pseudomallei with cytidine and FOL694, 2-(thiophen-2-yl)phenyl methanol
Descriptor: (2-thiophen-2-ylphenyl)methanol, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, 4-AMINO-1-BETA-D-RIBOFURANOSYL-2(1H)-PYRIMIDINONE, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2010-09-29
Release date:2010-11-10
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Leveraging structure determination with fragment screening for infectious disease drug targets: MECP synthase from Burkholderia pseudomallei.
J Struct Funct Genomics, 12, 2011
3OY4
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BU of 3oy4 by Molmil
Crystal Structure of HIV-1 L76V Protease in Complex with the Protease Inhibitor Darunavir.
Descriptor: (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, ACETATE ION, HIV-1 PROTEASE, ...
Authors:Schiffer, C.A, Nalivaika, E.A, Bandaranayake, R.M.
Deposit date:2010-09-22
Release date:2011-02-09
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Crystal Structure of HIV-1 L76V Protease in Complex with the Protease Inhibitor Darunavir.
To be Published
3OYC
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BU of 3oyc by Molmil
Crystal structure of the Prototype Foamy Virus (PFV) intasome in complex with magnesium and the INSTI PICA
Descriptor: 9-(4-fluorobenzyl)-N-hydroxy-9H-beta-carboline-3-carboxamide, AMMONIUM ION, DNA (5'-D(*AP*TP*TP*GP*TP*CP*AP*TP*GP*GP*AP*AP*TP*TP*TP*CP*GP*CP*A)-3'), ...
Authors:Hare, S, Cherepanov, P.
Deposit date:2010-09-23
Release date:2010-11-17
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:Molecular mechanisms of retroviral integrase inhibition and the evolution of viral resistance.
Proc.Natl.Acad.Sci.USA, 107, 2010
3P3E
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BU of 3p3e by Molmil
Crystal Structure of the PSEUDOMONAS AERUGINOSA LpxC/LPC-009 complex
Descriptor: N-[(1S,2R)-2-hydroxy-1-(hydroxycarbamoyl)propyl]-4-(4-phenylbuta-1,3-diyn-1-yl)benzamide, NITRATE ION, SODIUM ION, ...
Authors:Lee, C.-J, Zhou, P.
Deposit date:2010-10-04
Release date:2011-01-05
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.28 Å)
Cite:Species-specific and inhibitor-dependent conformations of LpxC: implications for antibiotic design.
Chem.Biol., 18, 2011
3OZD
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BU of 3ozd by Molmil
Crystal Structure of human 5'-deoxy-5'-methyladenosine phosphorylase in complex with pCl-phenylthioDADMeImmA
Descriptor: (3R,4S)-1-[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-{[(4-chlorophenyl)sulfanyl]methyl}pyrrolidin-3-ol, S-methyl-5'-thioadenosine phosphorylase
Authors:Ho, M, Guan, R, Almo, S.C, Schramm, V.L.
Deposit date:2010-09-24
Release date:2011-09-28
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure of human 5'-deoxy-5'-methyladenosine phosphorylase
to be published
3P02
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BU of 3p02 by Molmil
Crystal structure of a protein of unknown function (BACOVA_00267) from Bacteroides ovatus at 1.55 A resolution
Descriptor: 1,2-ETHANEDIOL, Uncharacterized protein
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2010-09-27
Release date:2010-10-20
Last modified:2023-02-01
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystal structure of a protein of unknown function (BACOVA_00267) from Bacteroides ovatus at 1.55 A resolution
To be published
3P62
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BU of 3p62 by Molmil
Wild-type pentaerythritol tetranitrate reductase containing a C-terminal 8-histidine tag
Descriptor: ACETATE ION, FLAVIN MONONUCLEOTIDE, Pentaerythritol tetranitrate reductase
Authors:Toogood, H.S, Hulley, M.E, Scrutton, N.S.
Deposit date:2010-10-11
Release date:2010-11-24
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Focused Directed Evolution of Pentaerythritol Tetranitrate Reductase by Using Automated Anaerobic Kinetic Screening of Site-Saturated Libraries
Chembiochem, 11, 2010
3OVJ
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BU of 3ovj by Molmil
Structure of an amyloid forming peptide KLVFFA from amyloid beta in complex with orange G
Descriptor: 7-hydroxy-8-[(E)-phenyldiazenyl]naphthalene-1,3-disulfonic acid, KLVFFA hexapeptide segment from Amyloid beta
Authors:Landau, M, Eisenberg, D.
Deposit date:2010-09-16
Release date:2011-07-06
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Towards a pharmacophore for amyloid.
Plos Biol., 9, 2011
3OVM
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BU of 3ovm by Molmil
X-ray Structural study of quinone reductase II inhibition by compounds with micromolar to nanomolar range IC50 values
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Ribosyldihydronicotinamide dehydrogenase [quinone], ZINC ION, ...
Authors:Pegan, S.D, Sturdy, M, Ferry, G, Delagrange, P, Boutin, J.A.
Deposit date:2010-09-16
Release date:2011-05-25
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:X-ray structural studies of quinone reductase 2 nanomolar range inhibitors.
Protein Sci., 20, 2011
3O6X
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BU of 3o6x by Molmil
Crystal Structure of the type III Glutamine Synthetase from Bacteroides fragilis
Descriptor: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, Glutamine synthetase, ...
Authors:van Rooyen, J.M, Belrhali, H, Abratt, V.R, Sewell, B.T.
Deposit date:2010-07-29
Release date:2011-03-09
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Crystal Structure of Type III Glutamine Synthetase: Surprising Reversal of the Inter-Ring Interface.
Structure, 19, 2011
3OES
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BU of 3oes by Molmil
Crystal structure of the small GTPase RhebL1
Descriptor: GTPase RhebL1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
Authors:Nedyalkova, L, Zhong, N, Tempel, W, Tong, Y, Shen, L, Loppnau, P, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC)
Deposit date:2010-08-13
Release date:2010-08-25
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.301 Å)
Cite:Crystal structure of the small GTPase RhebL1
to be published
2PEB
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BU of 2peb by Molmil
Crystal structure of a putative dioxygenase (npun_f1925) from nostoc punctiforme pcc 73102 at 1.46 A resolution
Descriptor: 1,2-ETHANEDIOL, TETRAETHYLENE GLYCOL, UNKNOWN LIGAND, ...
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2007-04-02
Release date:2007-04-17
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:Crystal structure of putative dioxygenase (ZP_00109509.1) from Nostoc punctiforme PCC 73102 at 1.46 A resolution
To be published
3OF4
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BU of 3of4 by Molmil
Crystal structure of a FMN/FAD- and NAD(P)H-dependent nitroreductase (nfnB, IL2077) from Idiomarina loihiensis L2TR at 1.90 A resolution
Descriptor: ACETATE ION, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2010-08-13
Release date:2010-08-25
Last modified:2023-02-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of a FMN/FAD- and NAD(P)H-dependent nitroreductase (nfnB, IL2077) from Idiomarina loihiensis L2TR at 1.90 A resolution
To be published
3OAJ
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BU of 3oaj by Molmil
CRYSTAL STRUCTURE OF putative dioxygenase from Bacillus subtilis subsp. subtilis str. 168
Descriptor: Putative ring-cleaving dioxygenase mhqO, SULFATE ION, ZINC ION
Authors:Malashkevich, V.N, Toro, R, Seidel, R, Garrett, S, Foti, R, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC)
Deposit date:2010-08-05
Release date:2010-08-18
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:CRYSTAL STRUCTURE OF putative dioxygenase from Bacillus subtilis subsp. subtilis str. 168
To be Published
2B25
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BU of 2b25 by Molmil
Human putative tRNA(1-methyladenosine)methyltransferase
Descriptor: S-ADENOSYLMETHIONINE, UNKNOWN ATOM OR ION, hypothetical protein
Authors:Tempel, W, Wu, H, Dong, A, Zeng, H, Loppnau, P, Arrowsmith, C, Edwards, A, Sundstrom, M, Weigelt, J, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
Deposit date:2005-09-16
Release date:2005-09-27
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Human putative tRNA(1-methyladenosine)methyltransferase
To be Published
3OHA
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BU of 3oha by Molmil
Yeast DNA polymerase eta inserting dCTP opposite an 8oxoG lesion
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*GP*TP*CP*CP*TP*CP*CP*CP*CP*TP*(DOC))-3', 5'-D(P*TP*(8OG)P*GP*AP*GP*GP*GP*GP*AP*GP*GP*AP*C)-3', ...
Authors:Silverstein, T.D, Jain, R, Aggarwal, A.K.
Deposit date:2010-08-17
Release date:2010-12-22
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for error-free replication of oxidatively damaged DNA by yeast DNA polymerase eta.
Structure, 18, 2010
3OF7
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BU of 3of7 by Molmil
The Crystal Structure of Prp20p from Saccharomyces cerevisiae and Its Binding Properties to Gsp1p and Histones
Descriptor: Regulator of chromosome condensation
Authors:Wu, F, Liu, Y, Zhu, Z, Huang, H, Ding, B, Wu, J, Shi, Y.
Deposit date:2010-08-14
Release date:2011-03-23
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The 1.9A crystal structure of Prp20p from Saccharomyces cerevisiae and its binding properties to Gsp1p and histones.
J.Struct.Biol., 174, 2011
3OFF
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BU of 3off by Molmil
Structured Domain of Drosophila melanogaster Boca p65 2 2 Crystal form
Descriptor: ACETATE ION, LDLR chaperone boca, SODIUM ION, ...
Authors:Collins, M.N, Hendrickson, W.A.
Deposit date:2010-08-14
Release date:2011-03-02
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.002 Å)
Cite:Structural Characterization of the Boca/Mesd Maturation Factors for LDL-Receptor-Type beta-Propeller Domains
Structure, 2011
1YDK
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BU of 1ydk by Molmil
Crystal structure of the I219A mutant of human glutathione transferase A1-1 with S-hexylglutathione
Descriptor: Glutathione S-transferase A1, S-HEXYLGLUTATHIONE
Authors:Kuhnert, D.C, Sayed, Y, Mosebi, S, Sayed, M, Sewell, T, Dirr, H.W.
Deposit date:2004-12-24
Release date:2005-06-07
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Tertiary Interactions Stabilise the C-terminal Region of Human Glutathione Transferase A1-1: a Crystallographic and Calorimetric Study.
J.Mol.Biol., 349, 2005
3OG4
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BU of 3og4 by Molmil
The crystal structure of human interferon lambda 1 complexed with its high affinity receptor in space group P21212
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin 28 receptor, alpha (Interferon, ...
Authors:Miknis, Z.J, Magracheva, E, Lei, W, Zdanov, A, Kotenko, S.V, Wlodawer, A.
Deposit date:2010-08-16
Release date:2010-10-20
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Crystal structure of the complex of human interferon-lambda1 with its high affinity receptor interferon-lambdaR1.
J.Mol.Biol., 404, 2010
3O7T
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BU of 3o7t by Molmil
Crystal Structure of Cyclophilin A from Moniliophthora perniciosa
Descriptor: Cyclophilin A
Authors:Monzani, P.S, Pereira, H.M, Gramacho, K.P, Meirelles, F.V, Oliva, G, Cascardo, J.C.M.
Deposit date:2010-07-31
Release date:2011-08-10
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal Structures of apo-cyclophilin and bounded cyclosporine A from Moniliophthora perniciosa
To be Published
3OB2
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BU of 3ob2 by Molmil
Crystal structure of c-Cbl TKB domain in complex with double phosphorylated EGFR peptide
Descriptor: 12-meric peptide from Epidermal growth factor receptor, E3 ubiquitin-protein ligase CBL
Authors:Sun, Q, Sivaraman, J.
Deposit date:2010-08-06
Release date:2010-08-18
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Additional serine/threonine phosphorylation reduces binding affinity but preserves interface topography of substrate proteins to the c-Cbl TKB domain
Plos One, 5, 2010
3OFG
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BU of 3ofg by Molmil
Structured Domain of Caenorhabditis elegans BMY-1
Descriptor: Boca/mesd chaperone for ywtd beta-propeller-egf protein 1, CHLORIDE ION
Authors:Collins, M.N, Hendrickson, W.A.
Deposit date:2010-08-14
Release date:2011-03-02
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.367 Å)
Cite:Structural Characterization of the Boca/Mesd Maturation Factors for LDL-Receptor-Type beta-Propeller Domains
Structure, 2011
2PM9
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BU of 2pm9 by Molmil
Crystal structure of yeast Sec13/31 vertex element of the COPII vesicular coat
Descriptor: Protein transport protein SEC13, Protein transport protein SEC31
Authors:Goldberg, J, Fath, S, Mancias, J.D, Bi, X.
Deposit date:2007-04-20
Release date:2007-07-03
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure and Organization of Coat Proteins in the COPII Cage.
Cell(Cambridge,Mass.), 129, 2007
3OBZ
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BU of 3obz by Molmil
Crystal structure of human phytanoyl-COA dioxygenase phyhd1 2-oxoglutarate and iron complex
Descriptor: 2-OXOGLUTARIC ACID, FE (II) ION, Phytanoyl-CoA dioxygenase domain-containing protein 1
Authors:Zhang, Z, McDonough, M.A, Schofield, C.J.
Deposit date:2010-08-09
Release date:2010-09-01
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal Structure of Human PHYHD1, a Non-Heme Fe(II) and 2-Oxoglutarate Dependent Oxygenase Related to Phytanoyl-CoA Hydroxylase
To be Published

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