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3OY4

Crystal Structure of HIV-1 L76V Protease in Complex with the Protease Inhibitor Darunavir.

Summary for 3OY4
Entry DOI10.2210/pdb3oy4/pdb
Related3OXV 3OXW 3OXX
DescriptorHIV-1 PROTEASE, PHOSPHATE ION, ACETATE ION, ... (5 entities in total)
Functional Keywordshiv-1 protease, inhibitor resistance, aids, aspartyl protease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceHuman immunodeficiency virus type 1 (HIV-1)
Cellular locationGag-Pol polyprotein: Host cell membrane; Lipid-anchor. Matrix protein p17: Virion membrane; Lipid- anchor . Capsid protein p24: Virion . Nucleocapsid protein p7: Virion . Reverse transcriptase/ribonuclease H: Virion . Integrase: Virion : P03369
Total number of polymer chains2
Total formula weight22944.38
Authors
Schiffer, C.A.,Nalivaika, E.A.,Bandaranayake, R.M. (deposition date: 2010-09-22, release date: 2011-02-09, Last modification date: 2024-02-21)
Primary citationSchiffer, C.A.,Nalivaika, E.A.,Bandaranayake, R.M.
Crystal Structure of HIV-1 L76V Protease in Complex with the Protease Inhibitor Darunavir.
To be Published,
Experimental method
X-RAY DIFFRACTION (1.76 Å)
Structure validation

217705

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