3OG4

The crystal structure of human interferon lambda 1 complexed with its high affinity receptor in space group P21212

Summary for 3OG4

Entry DOI	10.2210/pdb3og4/pdb
Related	3G9V 3HHC 3OG6
Descriptor	Interleukin-29, Interleukin 28 receptor, alpha (Interferon, lambda receptor), beta-D-mannopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
Functional Keywords	helical bundle, fibronectin type iii domains, beta-sandwich, cytokine, cytokine receptor, il-10r2, membrane, cytokine-cytokine receptor complex, cytokine/cytokine receptor
Biological source	Homo sapiens (human) More
Total number of polymer chains	2
Total formula weight	45924.29
Authors	Miknis, Z.J.,Magracheva, E.,Lei, W.,Zdanov, A.,Kotenko, S.V.,Wlodawer, A. (deposition date: 2010-08-16, release date: 2010-10-20, Last modification date: 2023-09-06)
Primary citation	Miknis, Z.J.,Magracheva, E.,Li, W.,Zdanov, A.,Kotenko, S.V.,Wlodawer, A. Crystal structure of the complex of human interferon-lambda1 with its high affinity receptor interferon-lambdaR1. J.Mol.Biol., 404:650-664, 2010 Cited by PubMed: 20934432 DOI: 10.1016/j.jmb.2010.09.068 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.16 Å)

Structure validation