3OHA
Yeast DNA polymerase eta inserting dCTP opposite an 8oxoG lesion
Summary for 3OHA
Entry DOI | 10.2210/pdb3oha/pdb |
Related | 3MFH 3MFI 3OHB |
Descriptor | DNA polymerase eta, 5'-D(*GP*TP*CP*CP*TP*CP*CP*CP*CP*TP*(DOC))-3', 5'-D(P*TP*(8OG)P*GP*AP*GP*GP*GP*GP*AP*GP*GP*AP*C)-3', ... (7 entities in total) |
Functional Keywords | protein-dna complex, nucleotidyltransferase, dna-directed dna polymerase, dna replication, dna repair, dna binding, nucleotide binding, metal binding, nucleus, transferase-dna complex, transferase/dna |
Biological source | Saccharomyces cerevisiae (brewer's yeast,lager beer yeast,yeast) |
Cellular location | Nucleus : Q04049 |
Total number of polymer chains | 3 |
Total formula weight | 66960.14 |
Authors | Silverstein, T.D.,Jain, R.,Aggarwal, A.K. (deposition date: 2010-08-17, release date: 2010-12-22, Last modification date: 2023-09-06) |
Primary citation | Silverstein, T.D.,Jain, R.,Johnson, R.E.,Prakash, L.,Prakash, S.,Aggarwal, A.K. Structural basis for error-free replication of oxidatively damaged DNA by yeast DNA polymerase eta. Structure, 18:1463-1470, 2010 Cited by PubMed: 21070945DOI: 10.1016/j.str.2010.08.019 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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