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3OHA

Yeast DNA polymerase eta inserting dCTP opposite an 8oxoG lesion

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DNA polymerase etapolymer52058813.41UniProt (Q04049)
Pfam (PF00817)
Pfam (PF11799)
Saccharomyces cerevisiae (brewer's yeast lager beer yeast yeast)Radiation-sensitive protein 30
2B
(P)
5'-D(*GP*TP*CP*CP*TP*CP*CP*CP*CP*TP*(DOC))-3'polymer113205.11
3C
(T)
5'-D(P*TP*(8OG)P*GP*AP*GP*GP*GP*GP*AP*GP*GP*AP*C)-3'polymer134137.71
4D
(A)
2'-DEOXYCYTIDINE-5'-TRIPHOSPHATEnon-polymer467.21Chemie (DCP)
5E, F, G
(A)
SULFATE IONnon-polymer96.13Chemie (SO4)
6H, I
(A)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
7J, K, L
(A, P, T)
waterwater18.0705Chemie (HOH)
Sequence modifications
A: 1 - 513 (UniProt: Q04049)
PDBExternal DatabaseDetails
Gly -6-expression tag
Pro -5-expression tag
Gly -4-expression tag
Gly -3-expression tag
Asp -2-expression tag
Pro -1-expression tag
His 0-expression tag
Ala 140Lys 140engineered mutation
Trp 144Ser 144engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight66156.2
Non-Polymers*Number of molecules6
Total formula weight804.0
All*Total formula weight66960.1
*Water molecules are not included.

238895

PDB entries from 2025-07-16

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