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5YG7
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BU of 5yg7 by Molmil
Crystal structure of ribose-1,5-bisphosphate isomerase mutant D204N from Pyrococcus horikoshii OT3 in complex with ribose-1,5-bisphosphate and GMP
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, 1,5-di-O-phosphono-alpha-D-ribofuranose, GUANOSINE-5'-MONOPHOSPHATE, ...
Authors:Gogoi, P, Kanaujia, S.P.
Deposit date:2017-09-22
Release date:2018-02-14
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A presumed homologue of the regulatory subunits of eIF2B functions as ribose-1,5-bisphosphate isomerase in Pyrococcus horikoshii OT3.
Sci Rep, 8, 2018
5YFJ
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BU of 5yfj by Molmil
Crystal structure of ribose-1,5-bisphosphate isomerase from Pyrococcus horikoshii OT3 in complex with ribulose-1,5-bisphosphate
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Gogoi, P, Kanaujia, S.P.
Deposit date:2017-09-21
Release date:2018-02-14
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A presumed homologue of the regulatory subunits of eIF2B functions as ribose-1,5-bisphosphate isomerase in Pyrococcus horikoshii OT3.
Sci Rep, 8, 2018
5YG5
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BU of 5yg5 by Molmil
Crystal structure of ribose-1,5-bisphosphate isomerase from Pyrococcus horikoshii OT3 in complex with ribulose-1,5-bisphosphate and GMP
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, DI(HYDROXYETHYL)ETHER, GUANOSINE-5'-MONOPHOSPHATE, ...
Authors:Gogoi, P, Kanaujia, S.P.
Deposit date:2017-09-22
Release date:2018-02-14
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:A presumed homologue of the regulatory subunits of eIF2B functions as ribose-1,5-bisphosphate isomerase in Pyrococcus horikoshii OT3.
Sci Rep, 8, 2018
5YFU
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BU of 5yfu by Molmil
Crystal structure of ribose-1,5-bisphosphate isomerase from Pyrococcus horikoshii OT3 in complex with ribulose-1,5-bisphosphate and AMP
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE MONOPHOSPHATE, POTASSIUM ION, ...
Authors:Gogoi, P, Kanaujia, S.P.
Deposit date:2017-09-22
Release date:2018-02-14
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:A presumed homologue of the regulatory subunits of eIF2B functions as ribose-1,5-bisphosphate isomerase in Pyrococcus horikoshii OT3.
Sci Rep, 8, 2018
5YG8
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BU of 5yg8 by Molmil
Crystal structure of ribose-1,5-bisphosphate isomerase from Pyrococcus horikoshii OT3 in complex with ribulose-1,5-bisphosphate, AMP and GMP
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE MONOPHOSPHATE, GUANOSINE-5'-MONOPHOSPHATE, ...
Authors:Gogoi, P, Kanaujia, S.P.
Deposit date:2017-09-22
Release date:2018-02-14
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A presumed homologue of the regulatory subunits of eIF2B functions as ribose-1,5-bisphosphate isomerase in Pyrococcus horikoshii OT3.
Sci Rep, 8, 2018
5YG9
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BU of 5yg9 by Molmil
Crystal structure of ribose-1,5-bisphosphate isomerase mutant C135S from Pyrococcus horikoshii OT3 in complex with ribose-1,5-bisphosphate, AMP and GMP
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,5-di-O-phosphono-alpha-D-ribofuranose, ADENOSINE MONOPHOSPHATE, ...
Authors:Gogoi, P, Kanaujia, S.P.
Deposit date:2017-09-22
Release date:2018-02-14
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A presumed homologue of the regulatory subunits of eIF2B functions as ribose-1,5-bisphosphate isomerase in Pyrococcus horikoshii OT3.
Sci Rep, 8, 2018
5YFT
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BU of 5yft by Molmil
Crystal structure of ribose-1,5-bisphosphate isomerase mutant D204N from Pyrococcus horikoshii OT3 in complex with ribose-1,5-bisphosphate
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, 1,2-ETHANEDIOL, 1,5-di-O-phosphono-alpha-D-ribofuranose, ...
Authors:Gogoi, P, Kanaujia, S.P.
Deposit date:2017-09-22
Release date:2018-02-14
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:A presumed homologue of the regulatory subunits of eIF2B functions as ribose-1,5-bisphosphate isomerase in Pyrococcus horikoshii OT3.
Sci Rep, 8, 2018
5ZCY
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BU of 5zcy by Molmil
Crystal structure of archaeal translation initiation factor 1 at 1.5 Angstroms resolution
Descriptor: NITRATE ION, NITRITE ION, Protein translation factor SUI1 homolog
Authors:Gogoi, P, Kanaujia, S.P.
Deposit date:2018-02-22
Release date:2018-05-02
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Archaeal and eukaryal translation initiation factor 1 differ in their RNA interacting loops.
FEBS Lett., 592, 2018
6XH2
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BU of 6xh2 by Molmil
Co-crystal structure of HIV-1 TAR RNA in complex with lab-evolved RRM 6.6
Descriptor: TAR-BINDING PROTEIN 6.6, TRANS-ACTIVATION RESPONSE ELEMENT
Authors:Chavali, S.S, Jenkins, J.L, Wedekind, J.E.
Deposit date:2020-06-18
Release date:2020-10-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Co-crystal structures of HIV TAR RNA bound to lab-evolved proteins show key roles for arginine relevant to the design of cyclic peptide TAR inhibitors.
J.Biol.Chem., 295, 2020
7NKE
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BU of 7nke by Molmil
Crystal structure of human RXRalpha ligand binding domain in complex with 2,4-di-tert-butylphenol and a coactivator fragment
Descriptor: 2,4-di~{tert}-butylphenol, FORMIC ACID, Nuclear receptor coactivator 2, ...
Authors:Carivenc, C, Bourguet, W.
Deposit date:2021-02-17
Release date:2022-03-02
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:2,4-Di-tert-butylphenol Induces Adipogenesis in Human Mesenchymal Stem Cells by Activating Retinoid X Receptors.
Endocrinology, 164, 2023
3R1A
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BU of 3r1a by Molmil
Closed crystal structure of cytochrome P450 2B4 covalently bound to the mechanism-based inactivator tert-butylphenylacetylene
Descriptor: (4-tert-butylphenyl)acetaldehyde, Cytochrome P450 2B4, PROTOPORPHYRIN IX CONTAINING FE
Authors:Gay, S.C, Zhang, H, Stout, C.D, Hollenberg, P.F, Halpert, J.R.
Deposit date:2011-03-09
Release date:2011-05-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural Analysis of Mammalian Cytochrome P450 2B4 Covalently Bound to the Mechanism-Based Inactivator tert-Butylphenylacetylene: Insight into Partial Enzymatic Activity.
Biochemistry, 50, 2011
3R1B
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BU of 3r1b by Molmil
Open crystal structure of cytochrome P450 2B4 covalently bound to the mechanism-based inactivator tert-butylphenylacetylene
Descriptor: (4-tert-butylphenyl)acetaldehyde, 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, Cytochrome P450 2B4, ...
Authors:Gay, S.C, Zhang, H, Stout, C.D, Hollenberg, P.F, Halpert, J.R.
Deposit date:2011-03-09
Release date:2011-05-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Analysis of Mammalian Cytochrome P450 2B4 Covalently Bound to the Mechanism-Based Inactivator tert-Butylphenylacetylene: Insight into Partial Enzymatic Activity.
Biochemistry, 50, 2011
4LWP
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BU of 4lwp by Molmil
Crystal structure of PRMT6-SAH
Descriptor: Arginine N-methyltransferase, putative, IODIDE ION, ...
Authors:Zhu, Y, Wang, C, Shi, Y, Teng, M.
Deposit date:2013-07-28
Release date:2014-02-19
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.353 Å)
Cite:Crystal Structure of Arginine Methyltransferase 6 from Trypanosoma brucei
Plos One, 9, 2014
4LWO
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BU of 4lwo by Molmil
Crystal structure of PRMT6
Descriptor: Arginine N-methyltransferase, putative
Authors:Zhu, Y, Wang, C, Shi, Y, Teng, M.
Deposit date:2013-07-28
Release date:2014-02-19
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.203 Å)
Cite:Crystal Structure of Arginine Methyltransferase 6 from Trypanosoma brucei
Plos One, 9, 2014
3V83
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BU of 3v83 by Molmil
The 2.1 angstrom crystal structure of diferric human transferrin
Descriptor: BICARBONATE ION, FE (III) ION, HEXAETHYLENE GLYCOL, ...
Authors:Noinaj, N, Steere, A, Mason, A.B, Buchanan, S.K.
Deposit date:2011-12-22
Release date:2012-02-15
Last modified:2012-04-18
Method:X-RAY DIFFRACTION (2.102 Å)
Cite:Structural basis for iron piracy by pathogenic Neisseria.
Nature, 483, 2012
3RUX
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BU of 3rux by Molmil
Crystal structure of biotin-protein ligase BirA from Mycobacterium tuberculosis in complex with an acylsulfamide bisubstrate inhibitor
Descriptor: 5'-deoxy-5'-[({5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}sulfamoyl)amino]adenosine, BirA bifunctional protein
Authors:Geders, T.W, Finzel, B.C.
Deposit date:2011-05-05
Release date:2011-12-14
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Bisubstrate Adenylation Inhibitors of Biotin Protein Ligase from Mycobacterium tuberculosis.
Chem.Biol., 18, 2011
5JYO
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BU of 5jyo by Molmil
Allosteric inhibition of Kidney Isoform of Glutaminase
Descriptor: 2-(pyridin-2-yl)-N-(5-{4-[6-({[3-(trifluoromethoxy)phenyl]acetyl}amino)pyridazin-3-yl]butyl}-1,3,4-thiadiazol-2-yl)acetamide, Glutaminase kidney isoform, mitochondrial
Authors:Sivaraman, J, Jayaraman, S.
Deposit date:2016-05-15
Release date:2016-08-03
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.098 Å)
Cite:Structural basis for exploring the allosteric inhibition of human kidney type glutaminase.
Oncotarget, 7, 2016
5JYP
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BU of 5jyp by Molmil
Allosteric inhibition of Kidney Isoform of Glutaminase
Descriptor: 2-phenyl-~{N}-[5-[(1~{S},3~{S})-3-[5-(2-phenylethanoylamino)-1,3,4-thiadiazol-2-yl]cyclohexyl]-1,3,4-thiadiazol-2-yl]ethanamide, Glutaminase kidney isoform, mitochondrial
Authors:Ramachandran, S, Sivaraman, J.
Deposit date:2016-05-15
Release date:2016-08-03
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.74 Å)
Cite:Structural basis for exploring the allosteric inhibition of human kidney type glutaminase.
Oncotarget, 7, 2016
6AHO
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BU of 6aho by Molmil
Crystal structure of Kap114p
Descriptor: Importin subunit beta-5
Authors:Liao, C.C, Shankar, S, Ahmed, G.R, Hsia, K.C.
Deposit date:2018-08-20
Release date:2019-10-23
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.502 Å)
Cite:Karyopherin Kap114p-mediated trans-repression controls ribosomal gene expression under saline stress.
Embo Rep., 21, 2020
4KCW
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BU of 4kcw by Molmil
Pyruvate kinase (PYK) from Trypanosoma brucei soaked with oxalate
Descriptor: 2,6-di-O-phosphono-beta-D-fructofuranose, GLYCEROL, MAGNESIUM ION, ...
Authors:Zhong, W, Morgan, H.P, McNae, I.W, Michels, P.A.M, Fothergill-Gilmore, L.A, Walkinshaw, M.D.
Deposit date:2013-04-24
Release date:2014-01-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Pyruvate kinases have an intrinsic and conserved decarboxylase activity.
Biochem.J., 458, 2014
1GVF
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BU of 1gvf by Molmil
Structure of tagatose-1,6-bisphosphate aldolase
Descriptor: 1,2-ETHANEDIOL, PHOSPHOGLYCOLOHYDROXAMIC ACID, SODIUM ION, ...
Authors:Hall, D.R, Hunter, W.N.
Deposit date:2002-02-11
Release date:2002-06-18
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structure of Tagatose-1,6-Bisphosphate Aldolase; Insight Into Chiral Discrimination, Mechanism and Specificity of Class II Aldolases
J.Biol.Chem., 277, 2002
4E1N
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BU of 4e1n by Molmil
Crystal Structure of HIV-1 Integrase with a non-catayltic site inhibitor
Descriptor: (2S)-tert-butoxy[4-(8-fluoro-5-methyl-3,4-dihydro-2H-chromen-6-yl)-2-methylquinolin-3-yl]ethanoic acid, HIV-1 integrase
Authors:Lansdon, E.B.
Deposit date:2012-03-06
Release date:2012-04-25
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:New Class of HIV-1 Integrase (IN) Inhibitors with a Dual Mode of Action.
J.Biol.Chem., 287, 2012
4E1M
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BU of 4e1m by Molmil
Crystal Structure of HIV-1 Integrase with a non-catayltic site inhibitor
Descriptor: (2S)-tert-butoxy[4-(3,4-dimethylphenyl)-2-methylquinolin-3-yl]ethanoic acid, HIV-1 Integrase
Authors:Lansdon, E.B.
Deposit date:2012-03-06
Release date:2012-04-25
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:New Class of HIV-1 Integrase (IN) Inhibitors with a Dual Mode of Action.
J.Biol.Chem., 287, 2012
5BRJ
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BU of 5brj by Molmil
Structure of the bacteriophytochrome response regulator AtBRR
Descriptor: MAGNESIUM ION, Two component response regulator
Authors:Baker, A.W, Satyshur, K.A, Forest, K.T.
Deposit date:2015-05-31
Release date:2016-02-24
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.922 Å)
Cite:Arm-in-Arm Response Regulator Dimers Promote Intermolecular Signal Transduction.
J.Bacteriol., 198, 2016
8OS1
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BU of 8os1 by Molmil
X-ray structure of the Peroxisomal Targeting Signal 1 (PTS1) of Trypanosoma Cruzi PEX5 in complex with the PTS1 peptide
Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, ...
Authors:Napolitano, V, Blat, A, Popowicz, G.M, Dubin, G.
Deposit date:2023-04-17
Release date:2024-10-02
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural dynamics of the TPR domain of the peroxisomal cargo receptor Pex5 in Trypanosoma.
Int.J.Biol.Macromol., 280, 2024

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