6PJP
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6V8H
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![BU of 6v8h by Molmil](/molmil-images/mine/6v8h) | Crystal structure of Ara h 8.0201 | Descriptor: | Ara h 8 allergen isoform, SULFATE ION | Authors: | Offermann, L.R, Pote, S, Hurlburt, B.K, McBride, J.K, Chruszcz, M. | Deposit date: | 2019-12-11 | Release date: | 2020-12-16 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | Crystal structure of Ara h 8.0201 To Be Published
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8JLW
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![BU of 8jlw by Molmil](/molmil-images/mine/8jlw) | CCHFV envelope protein Gc in complex with Gc8 | Descriptor: | Glycoprotein C,CCHFV envelope protein Gc fusion loops, Mouse antibody Gc8 heavy chain, Mouse antibody Gc8 light chain | Authors: | Chong, T, Cao, S. | Deposit date: | 2023-06-03 | Release date: | 2024-01-24 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Neutralizing monoclonal antibodies against the Gc fusion loop region of Crimean-Congo hemorrhagic fever virus. Plos Pathog., 20, 2024
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6V9U
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![BU of 6v9u by Molmil](/molmil-images/mine/6v9u) | Crystal structure of human TLR8 ectodomain bound to small molecule antagonist 14c | Descriptor: | 2-(3,4-dimethoxyphenyl)-5-(piperidin-4-yl)-3-(propan-2-yl)-1H-indole, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Critton, D.A. | Deposit date: | 2019-12-16 | Release date: | 2020-08-12 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Discovery of Potent and Orally Bioavailable Small Molecule Antagonists of Toll-like Receptors 7/8/9 (TLR7/8/9). Acs Med.Chem.Lett., 11, 2020
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8JKD
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6PJ4
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6NZV
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![BU of 6nzv by Molmil](/molmil-images/mine/6nzv) | Crystal structure of HCV NS3/4A protease in complex with compound 12 | Descriptor: | (1aR,5S,8S,9S,10R,22aR)-5-tert-butyl-N-[(1R,2R)-2-(difluoromethyl)-1-{[(1-methylcyclopropyl)sulfonyl]carbamoyl}cyclopropyl]-9-ethyl-14-methoxy-3,6-dioxo-1,1a,3,4,5,6,9,10,18,19,20,21,22,22a-tetradecahydro-8H-7,10-methanocyclopropa[18,19][1,10,3,6]dioxadiazacyclononadecino[11,12-b]quinoxaline-8-carboxamide, HCV NS3/4A protease, SULFATE ION, ... | Authors: | Appleby, T.C, Taylor, J.G. | Deposit date: | 2019-02-14 | Release date: | 2019-07-10 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Discovery of the pan-genotypic hepatitis C virus NS3/4A protease inhibitor voxilaprevir (GS-9857): A component of Vosevi®. Bioorg.Med.Chem.Lett., 29, 2019
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6NYW
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![BU of 6nyw by Molmil](/molmil-images/mine/6nyw) | Structure of spastin AAA domain N527C mutant in complex with 8-fluoroquinazoline-based inhibitor | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, N-(5-tert-butyl-1H-pyrazol-3-yl)-8-fluoro-2-[(2R)-2-methylpiperazin-1-yl]quinazolin-4-amine, ... | Authors: | Pisa, R, Cupido, T, Kapoor, T.M. | Deposit date: | 2019-02-12 | Release date: | 2019-03-27 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.189 Å) | Cite: | Designing Allele-Specific Inhibitors of Spastin, a Microtubule-Severing AAA Protein. J. Am. Chem. Soc., 141, 2019
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6PWF
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6V8L
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![BU of 6v8l by Molmil](/molmil-images/mine/6v8l) | Crystal structure of Ara h 8.0201 | Descriptor: | Ara h 8 allergen isoform, SULFATE ION, icosanoic acid | Authors: | Pote, S, Offermann, L.R, Hurlburt, B.K, McBride, J.K, Chruszcz, M. | Deposit date: | 2019-12-11 | Release date: | 2020-12-16 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystal structure of Ara h 8.0201 To Be Published
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6V8J
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![BU of 6v8j by Molmil](/molmil-images/mine/6v8j) | Crystal structure of Ara h 8.0201 | Descriptor: | Ara h 8 allergen isoform, SODIUM ION, SULFATE ION | Authors: | Offermann, L.R, Pote, S, Hurlburt, B.K, McBride, J.K, Chruszcz, M. | Deposit date: | 2019-12-11 | Release date: | 2020-12-16 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystal structure of Ara h 8.0201 To Be Published
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8JHP
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8OFN
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![BU of 8ofn by Molmil](/molmil-images/mine/8ofn) | Structure of the yellow fever virus (Asibi strain) dimeric envelope protein | Descriptor: | Envelope glycoprotein, SULFATE ION | Authors: | Covernton, E, Vaney, M.C, Barba-Spaeth, G, Rey, F.A. | Deposit date: | 2023-03-16 | Release date: | 2023-08-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.48 Å) | Cite: | New insight into flavivirus maturation from structure/function studies of the yellow fever virus envelope protein complex. Mbio, 14, 2023
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2IMI
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![BU of 2imi by Molmil](/molmil-images/mine/2imi) | Structures of an Insect Epsilon-class Glutathione S-transferase from the Malaria Vector Anopheles Gambiae: Evidence for High DDT-detoxifying Activity | Descriptor: | Epsilon-class Glutathione S-transferase, GLUTATHIONE | Authors: | Wang, Y, Hemingway, J, Ranson, H, Meehan, E.J, Chen, L. | Deposit date: | 2006-10-02 | Release date: | 2007-10-09 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structure of an insect epsilon class glutathione S-transferase from the malaria vector Anopheles gambiae provides an explanation for the high DDT-detoxifying activity J.Struct.Biol., 164, 2008
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6O9L
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![BU of 6o9l by Molmil](/molmil-images/mine/6o9l) | Human holo-PIC in the closed state | Descriptor: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | Authors: | Yan, C.L, Dodd, T, He, Y, Tainer, J.A, Tsutakawa, S.E, Ivanov, I. | Deposit date: | 2019-03-14 | Release date: | 2019-05-29 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (7.2 Å) | Cite: | Transcription preinitiation complex structure and dynamics provide insight into genetic diseases. Nat.Struct.Mol.Biol., 26, 2019
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6QF7
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![BU of 6qf7 by Molmil](/molmil-images/mine/6qf7) | Crystal structures of the recombinant beta-Factor XIIa protease with bound Thr-Arg and Pro-Arg substrate mimetics | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Coagulation factor XII, ... | Authors: | Pathak, M, Mannal, R, Li, C, Bubacarr, G.K, Badraldin, K.H, Belviso, B.D, Camila, R.B, Dreveny, I, Fischer, P.M, Dekker, L.V, Oliva, M.L.V, Emsley, J. | Deposit date: | 2019-01-09 | Release date: | 2019-06-05 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | Crystal structures of the recombinant beta-factor XIIa protease with bound Thr-Arg and Pro-Arg substrate mimetics. Acta Crystallogr D Struct Biol, 75, 2019
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6V8M
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![BU of 6v8m by Molmil](/molmil-images/mine/6v8m) | Crystal structure of Ara h 8.0201 | Descriptor: | 8-ANILINO-1-NAPHTHALENE SULFONATE, Ara h 8 allergen isoform, SULFATE ION | Authors: | Pote, S, Offermann, L.R, Hurlburt, B.K, McBride, J.K, Chruszcz, M. | Deposit date: | 2019-12-11 | Release date: | 2020-12-16 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Crystal structure of Ara h 8.0201 To Be Published
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6V8S
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![BU of 6v8s by Molmil](/molmil-images/mine/6v8s) | Crystal structure of Ara h 8.0201 | Descriptor: | 8-ANILINO-1-NAPHTHALENE SULFONATE, Ara h 8 allergen isoform, SULFATE ION | Authors: | Pote, S, Offermann, L.R, Hurlburt, B.K, McBride, J.K, Chruszcz, M. | Deposit date: | 2019-12-12 | Release date: | 2020-12-16 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of Ara h 8.0201 To Be Published
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6OPF
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6VPP
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![BU of 6vpp by Molmil](/molmil-images/mine/6vpp) | Cryo-EM structure of microtubule-bound KLP61F motor with tail domain in the nucleotide-free state | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein Klp61F, ... | Authors: | Bodrug, T, Wilson-Kubalek, E.M, Nithianantham, S, Debs, G, Sindelar, C.V, Milligan, R, Al-Bassam, J. | Deposit date: | 2020-02-04 | Release date: | 2020-02-19 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | The kinesin-5 tail domain directly modulates the mechanochemical cycle of the motor domain for anti-parallel microtubule sliding. Elife, 9, 2020
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6Q9M
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![BU of 6q9m by Molmil](/molmil-images/mine/6q9m) | Central Fibronectin-III array of RIM-binding protein | Descriptor: | PHOSPHATE ION, RIM-binding protein, isoform F | Authors: | Driller, J.D, Habibi, S, Wahl, M.C, Loll, B. | Deposit date: | 2018-12-18 | Release date: | 2020-01-15 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.453 Å) | Cite: | RIM-binding protein couples synaptic vesicle recruitment to release sites. J.Cell Biol., 219, 2020
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6VPS
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![BU of 6vps by Molmil](/molmil-images/mine/6vps) | Cryo-EM structure of the amyloid core of Drosophila Orb2 isolated from head | Descriptor: | Translational regulator orb2 | Authors: | Hervas, R, Rau, M.J, Park, Y, Zhang, W, Murzin, A.G, Fitzpatrick, J.A.J, Scheres, S.H.W, Si, K. | Deposit date: | 2020-02-04 | Release date: | 2020-03-18 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Cryo-EM structure of a neuronal functional amyloid implicated in memory persistence in Drosophila Science, 367, 2020
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8HLS
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![BU of 8hls by Molmil](/molmil-images/mine/8hls) | Crystal structure of the sialidase Am1547 from A.muciniphila | Descriptor: | CHLORIDE ION, MAGNESIUM ION, Sialidase domain-containing protein | Authors: | Rui, B, Xinyue, T. | Deposit date: | 2022-11-30 | Release date: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | Structural analysis of a novel sialidase from Akkermansia muciniphila reveals a distinct catalytic motif in GH33 family To Be Published
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6VJ9
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6O9M
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![BU of 6o9m by Molmil](/molmil-images/mine/6o9m) | Structure of the human apo TFIIH | Descriptor: | CDK-activating kinase assembly factor MAT1, General transcription factor IIH subunit 1, General transcription factor IIH subunit 2, ... | Authors: | Yan, C.L, Dodd, T, He, Y, Tainer, J.A, Tsutakawa, S.E, Ivanov, I. | Deposit date: | 2019-03-14 | Release date: | 2019-05-29 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Transcription preinitiation complex structure and dynamics provide insight into genetic diseases. Nat.Struct.Mol.Biol., 26, 2019
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