6VPP
Cryo-EM structure of microtubule-bound KLP61F motor with tail domain in the nucleotide-free state
Summary for 6VPP
Entry DOI | 10.2210/pdb6vpp/pdb |
EMDB information | 21314 21315 |
Descriptor | Tubulin alpha-1A chain, Tubulin beta chain, Kinesin-like protein Klp61F, ... (6 entities in total) |
Functional Keywords | kinesin-5, klp61f, microtubules, mitotic spindles, nucleotide-free state, cell cycle, motor protein |
Biological source | Drosophila melanogaster (Fruit fly) More |
Total number of polymer chains | 3 |
Total formula weight | 143647.06 |
Authors | Bodrug, T.,Wilson-Kubalek, E.M.,Nithianantham, S.,Debs, G.,Sindelar, C.V.,Milligan, R.,Al-Bassam, J. (deposition date: 2020-02-04, release date: 2020-02-19, Last modification date: 2024-03-06) |
Primary citation | Bodrug, T.,Wilson-Kubalek, E.M.,Nithianantham, S.,Thompson, A.F.,Alfieri, A.,Gaska, I.,Major, J.,Debs, G.,Inagaki, S.,Gutierrez, P.,Gheber, L.,McKenney, R.J.,Sindelar, C.V.,Milligan, R.,Stumpff, J.,Rosenfeld, S.S.,Forth, S.T.,Al-Bassam, J. The kinesin-5 tail domain directly modulates the mechanochemical cycle of the motor domain for anti-parallel microtubule sliding. Elife, 9:-, 2020 Cited by PubMed: 31958056DOI: 10.7554/eLife.51131 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.4 Å) |
Structure validation
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