6O9M

Structure of the human apo TFIIH

Summary for 6O9M

• Entry DOI: 10.2210/pdb6o9m/pdb
• EMDB information: 3802
• Descriptor: TFIIH basal transcription factor complex helicase XPD subunit, ZINC ION, General transcription factor IIH subunit 1, ... (10 entities in total)
• Functional Keywords: transcription initiation, molecular dynamics, gene regulation, community network analysis, global protein dynamics, rna polymerase, transcription
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 8
• Total formula weight: 414363.89

Authors

Yan, C.L.,Dodd, T.,He, Y.,Tainer, J.A.,Tsutakawa, S.E.,Ivanov, I. (deposition date: 2019-03-14, release date: 2019-05-29, Last modification date: 2024-03-13)

• Primary citation: Yan, C.,Dodd, T.,He, Y.,Tainer, J.A.,Tsutakawa, S.E.,Ivanov, I.; Transcription preinitiation complex structure and dynamics provide insight into genetic diseases.; Nat.Struct.Mol.Biol., 26:397-406, 2019; PubMed: 31110295; DOI: 10.1038/s41594-019-0220-3

Experimental method

ELECTRON MICROSCOPY (4.4 Å)