6QF7

Crystal structures of the recombinant beta-Factor XIIa protease with bound Thr-Arg and Pro-Arg substrate mimetics

Summary for 6QF7

• Entry DOI: 10.2210/pdb6qf7/pdb
• Related: 6GT6
• Related PRD ID: PRD_000020 PRD_900001
• Descriptor: Maltodextrin-binding protein, Coagulation factor XII, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• Functional Keywords: coagulation factor xii; serine protease; crystal structure; inhibitor complex, blood clotting
• Biological source: Escherichia coli; More
• Total number of polymer chains: 4
• Total formula weight: 137711.11

Authors

Pathak, M.,Mannal, R.,Li, C.,Bubacarr, G.K.,Badraldin, K.H.,Belviso, B.D.,Camila, R.B.,Dreveny, I.,Fischer, P.M.,Dekker, L.V.,Oliva, M.L.V.,Emsley, J. (deposition date: 2019-01-09, release date: 2019-06-05, Last modification date: 2020-07-29)

• Primary citation: Pathak, M.,Manna, R.,Li, C.,Kaira, B.G.,Hamad, B.K.,Belviso, B.D.,Bonturi, C.R.,Dreveny, I.,Fischer, P.M.,Dekker, L.V.,Oliva, M.L.V.,Emsley, J.; Crystal structures of the recombinant beta-factor XIIa protease with bound Thr-Arg and Pro-Arg substrate mimetics.; Acta Crystallogr D Struct Biol, 75:578-591, 2019; PubMed: 31205020; DOI: 10.1107/S2059798319006910

Experimental method

X-RAY DIFFRACTION (4 Å)