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6KWR
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BU of 6kwr by Molmil
Crystal structure of enterovirus 71 polymerase elongation complex (ddCTP form)
Descriptor: 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, MAGNESIUM ION, RNA (31-MER), ...
Authors:Shi, W, Gong, P.
Deposit date:2019-09-08
Release date:2019-12-11
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A nucleobase-binding pocket in a viral RNA-dependent RNA polymerase contributes to elongation complex stability.
Nucleic Acids Res., 48, 2020
2XEB
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BU of 2xeb by Molmil
NMR STRUCTURE OF THE PROTEIN-UNBOUND SPLICEOSOMAL U4 SNRNA 5' STEM LOOP
Descriptor: 5'-R(P*GP*AP*UP*CP*GP*UP*AP*GP*CP*CP*AP*AP*UP*GP*AP* GP*GP*UP*U)-3', 5'-R(P*GP*CP*CP*GP*AP*GP*GP*CP*GP*CP*GP*AP*UP*C)-3'
Authors:Falb, M, Amata, I, Gabel, F, Simon, B, Carlomagno, T.
Deposit date:2010-05-12
Release date:2010-05-26
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structure of the K-turn U4 RNA: a combined NMR and SANS study.
Nucleic Acids Res., 38, 2010
6DNH
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BU of 6dnh by Molmil
Cryo-EM structure of human CPSF-160-WDR33-CPSF-30-PAS RNA complex at 3.4 A resolution
Descriptor: Cleavage and polyadenylation specificity factor subunit 1, Cleavage and polyadenylation specificity factor subunit 4, RNA (5'-R(P*AP*AP*UP*AP*AP*AP*C)-3'), ...
Authors:Sun, Y, Zhang, Y, Hamilton, K, Walz, T, Tong, L.
Deposit date:2018-06-06
Release date:2018-06-27
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Molecular basis for the recognition of the human AAUAAA polyadenylation signal.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5CZZ
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BU of 5czz by Molmil
Crystal structure of Staphylococcus aureus Cas9 in complex with sgRNA and target DNA (TTGAAT PAM)
Descriptor: 1,2-ETHANEDIOL, CRISPR-associated endonuclease Cas9, DNA (28-MER), ...
Authors:Nishimasu, H, Ishitani, R, Nureki, O.
Deposit date:2015-08-01
Release date:2015-09-02
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure of Staphylococcus aureus Cas9.
Cell, 162, 2015
5E8J
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BU of 5e8j by Molmil
Crystal structure of mRNA cap guanine-N7 methyltransferase in complex with RAM
Descriptor: GLYCEROL, RNMT-activating mini protein, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Petit, P, Cowling, V.
Deposit date:2015-10-14
Release date:2016-07-13
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Molecular basis of RNA guanine-7 methyltransferase (RNMT) activation by RAM.
Nucleic Acids Res., 44, 2016
3HJ7
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BU of 3hj7 by Molmil
Crystal structure of TILS C-terminal domain
Descriptor: CHLORIDE ION, tRNA(Ile)-lysidine synthase
Authors:Nakanishi, K, Bonnefond, L, Kimura, S, Suzuki, T, Ishitani, R, Nureki, O.
Deposit date:2009-05-21
Release date:2009-10-20
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for translational fidelity ensured by transfer RNA lysidine synthetase.
Nature, 461, 2009
8R5O
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BU of 8r5o by Molmil
Plastid-encoded RNA polymerase
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Webster, M.W, Pramanick, I, Vergara-Cruces, A.
Deposit date:2023-11-17
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (2.49 Å)
Cite:Structure of the plant plastid-encoded RNA polymerase.
Cell, 187, 2024
5VPO
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BU of 5vpo by Molmil
The 70S P-site ASL SufA6 complex
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Hong, S, Sunita, S, Dunkle, J.A, Maehigashi, T, Dunham, C.M.
Deposit date:2017-05-05
Release date:2018-09-26
Last modified:2018-11-07
Method:X-RAY DIFFRACTION (3.34 Å)
Cite:Mechanism of tRNA-mediated +1 ribosomal frameshifting.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6DU5
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BU of 6du5 by Molmil
Crystal structure of hMettl16 catalytic domain in complex with MAT2A 3'UTR hairpin 6
Descriptor: U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase, hp6-RNA (25-MER)
Authors:Doxtader, K, Wang, P, Nam, Y.
Deposit date:2018-06-19
Release date:2018-09-26
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (3.006 Å)
Cite:Structural Basis for Regulation of METTL16, an S-Adenosylmethionine Homeostasis Factor.
Mol. Cell, 71, 2018
8RAS
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BU of 8ras by Molmil
Plastid-encoded RNA polymerase transcription elongation complex
Descriptor: DNA (81-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Webster, M.W, Pramanick, I, Vergara-Cruces, A.
Deposit date:2023-12-01
Release date:2024-03-06
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (2.62 Å)
Cite:Structure of the plant plastid-encoded RNA polymerase.
Cell, 187, 2024
7R81
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BU of 7r81 by Molmil
Structure of the translating Neurospora crassa ribosome arrested by cycloheximide
Descriptor: 18S rRNA, 26S rRNA, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, ...
Authors:Shen, L, Su, Z, Yang, K, Wu, C, Becker, T, Bell-Pedersen, D, Zhang, J, Sachs, M.S.
Deposit date:2021-06-25
Release date:2021-12-01
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Structure of the translating Neurospora ribosome arrested by cycloheximide
Proc.Natl.Acad.Sci.USA, 118, 2021
8RDJ
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BU of 8rdj by Molmil
Plastid-encoded RNA polymerase transcription elongation complex (Integrated model)
Descriptor: DNA (81-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Webster, M.W, Pramanick, I, Vergara-Cruces, A.
Deposit date:2023-12-08
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (2.62 Å)
Cite:Structure of the plant plastid-encoded RNA polymerase.
Cell, 187, 2024
2GIS
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BU of 2gis by Molmil
Structure of the S-adenosylmethionine riboswitch mRNA regulatory element
Descriptor: IRIDIUM HEXAMMINE ION, MAGNESIUM ION, S-ADENOSYLMETHIONINE, ...
Authors:Montange, R.K, Batey, R.T.
Deposit date:2006-03-29
Release date:2006-07-04
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of the S-adenosylmethionine riboswitch regulatory mRNA element.
Nature, 441, 2006
8R6S
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BU of 8r6s by Molmil
Plastid-encoded RNA polymerase (Integrated model)
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Webster, M.W, Pramanick, I, Vergara-Cruces, A.
Deposit date:2023-11-22
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (2.49 Å)
Cite:Structure of the plant plastid-encoded RNA polymerase.
Cell, 187, 2024
4O61
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BU of 4o61 by Molmil
Structure of human ALKBH5 crystallized in the presence of citrate
Descriptor: CITRIC ACID, GLYCEROL, RNA demethylase ALKBH5, ...
Authors:Tempel, W, Chao, X, Liu, K, Dong, A, Cerovina, T, He, H, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2013-12-20
Release date:2014-02-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structures of human ALKBH5 demethylase reveal a unique binding mode for specific single-stranded N6-methyladenosine RNA demethylation.
J.Biol.Chem., 289, 2014
5W0M
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BU of 5w0m by Molmil
Structure of human TUT7 catalytic module (CM) in complex with U5 RNA
Descriptor: IODIDE ION, SULFATE ION, Terminal uridylyltransferase 7, ...
Authors:Faehnle, C.R, Walleshauser, J, Joshua-Tor, L.
Deposit date:2017-05-31
Release date:2017-06-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.298 Å)
Cite:Multi-domain utilization by TUT4 and TUT7 in control of let-7 biogenesis.
Nat. Struct. Mol. Biol., 24, 2017
6QW6
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BU of 6qw6 by Molmil
Structure of the human U5.U4/U6 tri-snRNP at 2.9A resolution.
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ...
Authors:Charenton, C, Wilkinson, M.E, Nagai, K.
Deposit date:2019-03-05
Release date:2019-04-17
Last modified:2020-10-07
Method:ELECTRON MICROSCOPY (2.92 Å)
Cite:Mechanism of 5' splice site transfer for human spliceosome activation.
Science, 364, 2019
7LIV
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BU of 7liv by Molmil
Structure of human transfer RNA visualized in the cytomegalovirus, a DNA virus
Descriptor: Major capsid protein, Small capsomere-interacting protein, Tegument protein pp150, ...
Authors:Liu, Y.T, Strugatsky, D, Liu, W, Zhou, Z.H.
Deposit date:2021-01-28
Release date:2021-09-15
Last modified:2021-11-17
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structure of human cytomegalovirus virion reveals host tRNA binding to capsid-associated tegument protein pp150.
Nat Commun, 12, 2021
8DPK
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BU of 8dpk by Molmil
structure of T. brucei RESC5
Descriptor: RESC5
Authors:Schumacher, M.A, Salinas, R, Cannistraci, E.
Deposit date:2022-07-15
Release date:2023-02-22
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Structure of the T. brucei kinetoplastid RNA editing substrate-binding complex core component, RESC5.
Plos One, 18, 2023
8DZJ
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BU of 8dzj by Molmil
Cryo-EM structure of Acidibacillus sulfuroxidans Cas12f in complex with sgRNA and target DNA
Descriptor: Non-target DNA strand, OrfB_Zn_ribbon domain-containing protein, ZINC ION, ...
Authors:Liu, C, Zhao, M.
Deposit date:2022-08-07
Release date:2023-07-12
Last modified:2023-11-08
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:An engineered hypercompact CRISPR-Cas12f system with boosted gene-editing activity.
Nat.Chem.Biol., 19, 2023
4V5D
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BU of 4v5d by Molmil
Structure of the Thermus thermophilus 70S ribosome in complex with mRNA, paromomycin, acylated A- and P-site tRNAs, and E-site tRNA.
Descriptor: 16S ribosomal RNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ...
Authors:Voorhees, R.M, Weixlbaumer, A, Loakes, D, Kelley, A.C, Ramakrishnan, V.
Deposit date:2009-03-24
Release date:2014-07-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Insights into substrate stabilization from snapshots of the peptidyl transferase center of the intact 70S ribosome.
Nat. Struct. Mol. Biol., 16, 2009
5DIZ
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BU of 5diz by Molmil
Crystal Structure of nuclear proteinaceous RNase P 2 (PRORP2) from A. thaliana
Descriptor: Proteinaceous RNase P 2, ZINC ION
Authors:Karasik, A, Shanmuganathan, A, Howard, M.J, Fierke, C.A, Koutmos, M.
Deposit date:2015-09-01
Release date:2015-12-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Nuclear Protein-Only Ribonuclease P2 Structure and Biochemical Characterization Provide Insight into the Conserved Properties of tRNA 5' End Processing Enzymes.
J.Mol.Biol., 428, 2016
2G1W
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BU of 2g1w by Molmil
NMR structure of the Aquifex aeolicus tmRNA pseudoknot PK1
Descriptor: 5'-R(*GP*GP*GP*GP*UP*GP*GP*CP*UP*CP*CP*CP*CP*UP*AP*AP*CP*AP*GP*CP*CP*G)-3'
Authors:Nonin-Lecomte, S, Dardel, F.
Deposit date:2006-02-15
Release date:2006-04-11
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:NMR structure of the Aquifex aeolicus tmRNA pseudoknot PK1: new insights into the recoding event of the ribosomal trans-translation.
Nucleic Acids Res., 34, 2006
4V7C
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BU of 4v7c by Molmil
Structure of the Ribosome with Elongation Factor G Trapped in the Pre-Translocation State (pre-translocation 70S*tRNA structure)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Brilot, A.F, Korostelev, A.A, Ermolenko, D.N, Grigorieff, N.
Deposit date:2013-11-20
Release date:2014-07-09
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (7.6 Å)
Cite:Structure of the ribosome with elongation factor G trapped in the pretranslocation state.
Proc.Natl.Acad.Sci.USA, 110, 2013
4V7D
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BU of 4v7d by Molmil
Structure of the Ribosome with Elongation Factor G Trapped in the Pre-Translocation State (pre-translocation 70S*tRNA*EF-G structure)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Brilot, A.F, Korostelev, A.A, Ermolenko, D.N, Grigorieff, N.
Deposit date:2013-11-21
Release date:2014-07-09
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (7.6 Å)
Cite:Structure of the ribosome with elongation factor G trapped in the pretranslocation state.
Proc.Natl.Acad.Sci.USA, 110, 2013

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