5E8J

Crystal structure of mRNA cap guanine-N7 methyltransferase in complex with RAM

Summary for 5E8J

• Entry DOI: 10.2210/pdb5e8j/pdb
• Related: 3BGV 3EPP
• Descriptor: mRNA cap guanine-N7 methyltransferase, RNMT-activating mini protein, GLYCEROL, ... (5 entities in total)
• Functional Keywords: mrna capping, mrna processing, translation
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 84776.59

Authors

Petit, P.,Cowling, V. (deposition date: 2015-10-14, release date: 2016-07-13, Last modification date: 2024-01-10)

• Primary citation: Varshney, D.,Petit, A.P.,Bueren-Calabuig, J.A.,Jansen, C.,Fletcher, D.A.,Peggie, M.,Weidlich, S.,Scullion, P.,Pisliakov, A.V.,Cowling, V.H.; Molecular basis of RNA guanine-7 methyltransferase (RNMT) activation by RAM.; Nucleic Acids Res., 44:10423-10436, 2016; PubMed: 27422871; DOI: 10.1093/nar/gkw637

Experimental method

X-RAY DIFFRACTION (2.35 Å)