5E8J
Crystal structure of mRNA cap guanine-N7 methyltransferase in complex with RAM
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | mRNA cap guanine-N7 methyltransferase | polymer | 312 | 36716.2 | 2 | UniProt (O43148) Pfam (PF03291) | Homo sapiens (Human) | RG7MT1,mRNA (guanine-N(7)-)-methyltransferase,mRNA cap methyltransferase,hcm1p |
| 2 | C, D (C, D) | RNMT-activating mini protein | polymer | 44 | 5241.7 | 2 | UniProt (Q9BTL3) Pfam (PF15320) | Homo sapiens (Human) | RAM,Protein FAM103A1 |
| 3 | E (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) PubChem (753) | |||
| 4 | F, G (A, B) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 2 | Chemie (SAH) PubChem (193) PubChem (13792) PubChem (189149) PubChem (439155) PubChem (5284331) PubChem (71170554) PubChem (13231890) PubChem (16760024) PubChem (25210495) PubChem (44361184) PubChem (177678424) PubChem (46936206) PubChem (21125603) PubChem (25203782) PubChem (52224400) PubChem (50989525) PubChem (51380914) PubChem (52224398) PubChem (6419189) PubChem (57544532) PubChem (59046843) PubChem (59170628) PubChem (164157219) PubChem (59576228) PubChem (66805708) PubChem (70689219) PubChem (70702054) PubChem (70832431) PubChem (118374891) PubChem (118560068) PubChem (126969526) PubChem (129105892) PubChem (143518505) PubChem (154578335) PubChem (163054214) PubChem (163335525) | |||
| 5 | H, I, J, K (A, B, C, D) | water | water | 18.0 | 219 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 83915.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 860.9 | |
| All* | Total formula weight | 84776.6 |
