5E8J
Crystal structure of mRNA cap guanine-N7 methyltransferase in complex with RAM
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | mRNA cap guanine-N7 methyltransferase | polymer | 312 | 36716.2 | 2 | UniProt (O43148) Pfam (PF03291) | Homo sapiens (Human) | RG7MT1,mRNA (guanine-N(7)-)-methyltransferase,mRNA cap methyltransferase,hcm1p |
| 2 | C, D (C, D) | RNMT-activating mini protein | polymer | 44 | 5241.7 | 2 | UniProt (Q9BTL3) Pfam (PF15320) | Homo sapiens (Human) | RAM,Protein FAM103A1 |
| 3 | E (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | F, G (A, B) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 2 | Chemie (SAH) | |||
| 5 | H, I, J, K (A, B, C, D) | water | water | 18.0 | 219 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 83915.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 860.9 | |
| All* | Total formula weight | 84776.6 |
