4C4W
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![BU of 4c4w by Molmil](/molmil-images/mine/4c4w) | Structure of a rare, non-standard sequence k-turn bound by L7Ae protein | Descriptor: | 50S RIBOSOMAL PROTEIN L7AE, DIHYDROGENPHOSPHATE ION, TSKT-23, ... | Authors: | Huang, L, Lilley, D.M.J. | Deposit date: | 2013-09-09 | Release date: | 2014-02-12 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Structure of a Rare, Non-Standard Sequence K-Turn Bound by L7Ae Protein Nucleic Acids Res., 42, 2014
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6NCQ
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![BU of 6ncq by Molmil](/molmil-images/mine/6ncq) | The dimerization domain of human SFPQ in space group C2221 | Descriptor: | Splicing factor, proline- and glutamine-rich | Authors: | Lee, M. | Deposit date: | 2018-12-12 | Release date: | 2019-06-26 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | A new crystal structure and small-angle X-ray scattering analysis of the homodimer of human SFPQ. Acta Crystallogr.,Sect.F, 75, 2019
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6OWJ
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![BU of 6owj by Molmil](/molmil-images/mine/6owj) | Zn-mediated polymerization of human SFPQ | Descriptor: | Splicing factor, proline- and glutamine-rich, ZINC ION | Authors: | Lee, M. | Deposit date: | 2019-05-10 | Release date: | 2020-02-05 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Structural basis of the zinc-induced cytoplasmic aggregation of the RNA-binding protein SFPQ. Nucleic Acids Res., 48, 2020
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5IFM
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![BU of 5ifm by Molmil](/molmil-images/mine/5ifm) | Human NONO (p54nrb) Homodimer | Descriptor: | CHLORIDE ION, GLYCEROL, Non-POU domain-containing octamer-binding protein, ... | Authors: | Knott, G.J, Bond, C.S. | Deposit date: | 2016-02-26 | Release date: | 2016-11-09 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | A crystallographic study of human NONO (p54(nrb)): overcoming pathological problems with purification, data collection and noncrystallographic symmetry. Acta Crystallogr D Struct Biol, 72, 2016
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5IFN
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![BU of 5ifn by Molmil](/molmil-images/mine/5ifn) | |
4A8X
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![BU of 4a8x by Molmil](/molmil-images/mine/4a8x) | Structure of the core ASAP complex | Descriptor: | HISTONE DEACETYLASE COMPLEX SUBUNIT SAP18, HOOK-LIKE, ISOFORM A, ... | Authors: | Murachelli, A.G, Ebert, J, Basquin, C, Le Hir, H, Conti, E. | Deposit date: | 2011-11-21 | Release date: | 2012-03-07 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The Structure of the Asap Core Complex Reveals the Existence of a Pinin-Containing Psap Complex Nat.Struct.Mol.Biol., 19, 2012
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4CQ1
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![BU of 4cq1 by Molmil](/molmil-images/mine/4cq1) | Crystal structure of the neuronal isoform of PTB | Descriptor: | CHLORIDE ION, POLYPYRIMIDINE TRACT-BINDING PROTEIN 2, ZINC ION | Authors: | Joshi, A, Buckroyd, A.N, Curry, S. | Deposit date: | 2014-02-10 | Release date: | 2014-02-19 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Solution and Crystal Structures of a C Terminal Fragment of the Neuronal Isoform of the Polypyrimidine Tract Binding Protein (Nptb) Peerj, 2, 2014
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8ANY
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![BU of 8any by Molmil](/molmil-images/mine/8any) | Human mitochondrial ribosome in complex with LRPPRC, SLIRP, A-site, P-site, E-site tRNAs and mRNA | Descriptor: | 1,4-DIAMINOBUTANE, 12S mitochondrial rRNA, 16S mitochondrial rRNA, ... | Authors: | Singh, V, Itoh, Y, Amunts, A. | Deposit date: | 2022-08-06 | Release date: | 2023-08-16 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (2.85 Å) | Cite: | Structural basis of LRPPRC-SLIRP-dependent translation by the
mitoribosome To Be Published
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8BY6
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![BU of 8by6 by Molmil](/molmil-images/mine/8by6) | Structure of the human nuclear cap-binding complex bound to NCBP3(560-620) and cap-analogue m7GpppG | Descriptor: | 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, Nuclear cap-binding protein subunit 1, Nuclear cap-binding protein subunit 2, ... | Authors: | Dubiez, E, Pellegrini, E, Foucher, A.E, Cusack, S, Kadlec, J. | Deposit date: | 2022-12-12 | Release date: | 2024-01-24 | Last modified: | 2024-01-31 | Method: | ELECTRON MICROSCOPY (3.19 Å) | Cite: | Structural basis for competitive binding of productive and degradative co-transcriptional effectors to the nuclear cap-binding complex. Cell Rep, 43, 2024
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8CG3
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![BU of 8cg3 by Molmil](/molmil-images/mine/8cg3) | |
8CGG
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![BU of 8cgg by Molmil](/molmil-images/mine/8cgg) | |
8CGH
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![BU of 8cgh by Molmil](/molmil-images/mine/8cgh) | |
5A5U
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![BU of 5a5u by Molmil](/molmil-images/mine/5a5u) | Structure of mammalian eIF3 in the context of the 43S preinitiation complex | Descriptor: | EUKARYOTIC INITIATION FACTOR 3, EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT B, EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT I | Authors: | des-Georges, A, Dhote, V, Kuhn, L, Hellen, C.U.T, Pestova, T.V, Frank, J, Hashem, Y. | Deposit date: | 2015-06-21 | Release date: | 2015-09-09 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (9 Å) | Cite: | Structure of Mammalian Eif3 in the Context of the 43S Preinitiation Complex. Nature, 525, 2015
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4YH8
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![BU of 4yh8 by Molmil](/molmil-images/mine/4yh8) | Structure of yeast U2AF complex | Descriptor: | Splicing factor U2AF 23 kDa subunit, Splicing factor U2AF 59 kDa subunit, ZINC ION | Authors: | Yoshida, H, Park, S.Y, Urano, T, Obayashi, E. | Deposit date: | 2015-02-27 | Release date: | 2015-08-12 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | A novel 3' splice site recognition by the two zinc fingers in the U2AF small subunit. Genes Dev., 29, 2015
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1N52
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![BU of 1n52 by Molmil](/molmil-images/mine/1n52) | Cap Binding Complex | Descriptor: | 20 kDa nuclear cap binding protein, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, 80 kDa nuclear cap binding protein, ... | Authors: | Calero, G, Wilson, K, Ly, T, Rios-Steiner, J, Clardy, J, Cerione, R. | Deposit date: | 2002-11-04 | Release date: | 2003-02-18 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.11 Å) | Cite: | Structural basis of m7GpppG binding to the nuclear cap-binding protein complex. Nat.Struct.Biol., 9, 2002
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1N54
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![BU of 1n54 by Molmil](/molmil-images/mine/1n54) | Cap Binding Complex m7GpppG free | Descriptor: | 20 kDa nuclear cap binding protein, 80 kDa nuclear cap binding protein, GLYCEROL | Authors: | Calero, G, Wilson, K, Ly, T, Rios-Steiner, J, Clardy, J, Cerione, R. | Deposit date: | 2002-11-04 | Release date: | 2003-02-18 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.72 Å) | Cite: | Structural basis of m7GpppG binding to the nuclear cap-binding protein complex. Nat.Struct.Biol., 9, 2002
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6PAI
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![BU of 6pai by Molmil](/molmil-images/mine/6pai) | |
7ONB
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![BU of 7onb by Molmil](/molmil-images/mine/7onb) | Structure of the U2 5' module of the A3'-SSA complex | Descriptor: | MINX, PHD finger-like domain-containing protein 5A, RNU2, ... | Authors: | Cretu, C, Pena, V. | Deposit date: | 2021-05-25 | Release date: | 2021-08-04 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural basis of intron selection by U2 snRNP in the presence of covalent inhibitors. Nat Commun, 12, 2021
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7OQB
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![BU of 7oqb by Molmil](/molmil-images/mine/7oqb) | The U2 part of Saccharomyces cerevisiae spliceosomal pre-A complex (delta BS-A ACT1) | Descriptor: | ACT1 pre-mRNA (delta-BS-A), Cold sensitive U2 snRNA suppressor 1, Pre-mRNA-processing ATP-dependent RNA helicase PRP5, ... | Authors: | Zhang, Z, Rigo, N, Dybkov, O, Fourmann, J, Will, C.L, Kumar, V, Urlaub, H, Stark, H, Luehrmann, R. | Deposit date: | 2021-06-03 | Release date: | 2021-08-11 | Last modified: | 2021-09-22 | Method: | ELECTRON MICROSCOPY (9 Å) | Cite: | Structural insights into how Prp5 proofreads the pre-mRNA branch site. Nature, 596, 2021
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7OQE
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![BU of 7oqe by Molmil](/molmil-images/mine/7oqe) | Saccharomyces cerevisiae spliceosomal pre-A complex (delta BS-A ACT1) | Descriptor: | 56 kDa U1 small nuclear ribonucleoprotein component, ACT1 pre-mRNA (delta BS-A), Cold sensitive U2 snRNA suppressor 1, ... | Authors: | Zhang, Z, Rigo, N, Dybkov, O, Fourmann, J, Will, C.L, Kumar, V, Urlaub, H, Stark, H, Luehrmann, R. | Deposit date: | 2021-06-03 | Release date: | 2021-08-11 | Last modified: | 2021-09-29 | Method: | ELECTRON MICROSCOPY (5.9 Å) | Cite: | Structural insights into how Prp5 proofreads the pre-mRNA branch site. Nature, 596, 2021
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7OQC
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![BU of 7oqc by Molmil](/molmil-images/mine/7oqc) | The U1 part of Saccharomyces cerevisiae spliceosomal pre-A complex (delta BS-A ACT1) | Descriptor: | 56 kDa U1 small nuclear ribonucleoprotein component, ACT1 pre-mRNA (delta BS-A),ACT1 pre-mRNA (delta BS-A),ACT1 pre-mRNA (delta BS-A),ACT1 pre-mRNA (delta BS-A),ACT1 pre-mRNA (delta BS-A),ACT1 pre-mRNA (delta BS-A),ACT1 pre-mRNA (delta BS-A),ACT1 pre-mRNA (delta BS-A),ACT1 pre-mRNA (delta BS-A), Pre-mRNA-processing factor 39, ... | Authors: | Zhang, Z, Rigo, N, Dybkov, O, Fourmann, J, Will, C.L, Kumar, V, Urlaub, H, Stark, H, Luehrmann, R. | Deposit date: | 2021-06-03 | Release date: | 2021-08-11 | Last modified: | 2021-09-29 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Structural insights into how Prp5 proofreads the pre-mRNA branch site. Nature, 596, 2021
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6Q0W
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![BU of 6q0w by Molmil](/molmil-images/mine/6q0w) | Structure of DDB1-DDA1-DCAF15 complex bound to Indisulam and RBM39 | Descriptor: | DDB1- and CUL4-associated factor 15, DET1- and DDB1-associated protein 1, DNA damage-binding protein 1, ... | Authors: | Faust, T, Yoon, H, Nowak, R.P, Donovan, K.A, Li, Z, Cai, Q, Eleuteri, N.A, Zhang, T, Gray, N.S, Fischer, E.S. | Deposit date: | 2019-08-02 | Release date: | 2019-11-13 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural complementarity facilitates E7820-mediated degradation of RBM39 by DCAF15. Nat.Chem.Biol., 16, 2020
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6Q0R
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![BU of 6q0r by Molmil](/molmil-images/mine/6q0r) | Structure of DDB1-DDA1-DCAF15 complex bound to E7820 and RBM39 | Descriptor: | 3-cyano-N-(3-cyano-4-methyl-1H-indol-7-yl)benzene-1-sulfonamide, DDB1- and CUL4-associated factor 15, DET1- and DDB1-associated protein 1, ... | Authors: | Faust, T, Yoon, H, Nowak, R.P, Donovan, K.A, Li, Z, Cai, Q, Eleuteri, N.A, Zhang, T, Gray, N.S, Fischer, E.S. | Deposit date: | 2019-08-02 | Release date: | 2019-11-13 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural complementarity facilitates E7820-mediated degradation of RBM39 by DCAF15. Nat.Chem.Biol., 16, 2020
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7PCV
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![BU of 7pcv by Molmil](/molmil-images/mine/7pcv) | |
7PY2
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![BU of 7py2 by Molmil](/molmil-images/mine/7py2) | Structure of pathological TDP-43 filaments from ALS with FTLD | Descriptor: | TAR DNA-binding protein 43 | Authors: | Arseni, D, Hasegawa, H, Murzin, A.G, Kametani, F, Arai, M, Yoshida, M, Falcon, B. | Deposit date: | 2021-10-08 | Release date: | 2021-12-15 | Last modified: | 2022-01-19 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Structure of pathological TDP-43 filaments from ALS with FTLD. Nature, 601, 2022
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