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7WK3	SARS-CoV-2 Omicron S-open Descriptor: Spike glycoprotein Authors: Li, J.W, Cong, Y. Deposit date: 2022-01-08 Release date: 2022-01-26 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Structural basis for ACE2 engagement and antibody evasion and neutralization of SARS-Co-2 Omicron varient To Be Published
7WK6	Cryo-EM structure of SARS-CoV-2 Omicron spike protein with human ACE2 (focus refinement on RBD-1/ACE2) Descriptor: Angiotensin-converting enzyme 2, Spike glycoprotein Authors: Han, W.Y, Wang, Y.F. Deposit date: 2022-01-08 Release date: 2022-02-02 Last modified: 2022-05-04 Method: ELECTRON MICROSCOPY (3.67 Å) Cite: Molecular basis of receptor binding and antibody neutralization of Omicron Nature, 604, 2022
6CK9	Crystal Structure of HIV-1 ConC_Base0 Prefusion Env Trimer in Complex with Human Antibody Fragment 3H109L and 35O22 variants at 3.5 Angstrom Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Lai, Y.-T, Kwong, P.D. Deposit date: 2018-02-27 Release date: 2018-04-25 Last modified: 2022-03-23 Method: X-RAY DIFFRACTION (2.714 Å) Cite: A Universal Approach to Optimize the Folding and Stability of Prefusion-Closed HIV-1 Envelope Trimers. Cell Rep, 23, 2018
7WM0	Cryo-EM structure of the Omicron RBD in complex with 35B5 Fab( local refinement of the RBD and 35B5 Fab) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of 35B5 Fab, Light chain of 35B5 Fab, ... Authors: Wang, X, Zhu, Y. Deposit date: 2022-01-14 Release date: 2022-08-17 Method: ELECTRON MICROSCOPY (3.35 Å) Cite: 35B5 antibody potently neutralizes SARS-CoV-2 Omicron by disrupting the N-glycan switch via a conserved spike epitope Cell Host Microbe, 30, 2022
7WT9	SARS-CoV-2 Omicron variant spike RBD in complex with Fab 9A8 Descriptor: Heavy chain of Fab 9A8, Light chain of Fab 9A8, Spike glycoprotein Authors: Wang, X, Wang, L. Deposit date: 2022-02-04 Release date: 2023-06-07 Method: ELECTRON MICROSCOPY (4.3 Å) Cite: A broader neutralizing antibody against all the current VOCs and VOIs targets unique epitope of SARS-CoV-2 RBD. Cell Discov, 8, 2022
7WT7	SARS-CoV-2 Omicron variant spike in complex with Fab 9A8 (State 1) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Fab 9A8, ... Authors: Wang, X, Wang, L. Deposit date: 2022-02-04 Release date: 2023-06-07 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: A broader neutralizing antibody against all the current VOCs and VOIs targets unique epitope of SARS-CoV-2 RBD. Cell Discov, 8, 2022
7WT8	SARS-CoV-2 Omicron variant spike in complex with Fab 9A8 (State 2) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Fab 9A8, ... Authors: Wang, X, Wang, L. Deposit date: 2022-02-04 Release date: 2023-06-07 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: A broader neutralizing antibody against all the current VOCs and VOIs targets unique epitope of SARS-CoV-2 RBD. Cell Discov, 8, 2022
7XCK	Cryo-EM structure of SARS-CoV-2 Omicron RBD in complex with S309 fab (local refinement) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, S309 heavy chain, S309 light chain, ... Authors: Gao, G.F, Qi, J.X, Zhao, Z.N, Xie, Y.F, Liu, S. Deposit date: 2022-03-24 Release date: 2022-08-31 Method: ELECTRON MICROSCOPY (2.5 Å) Cite: Omicron SARS-CoV-2 mutations stabilize spike up-RBD conformation and lead to a non-RBM-binding monoclonal antibody escape Nat Commun, 13, 2022
7XCH	Cryo-EM structure of SARS-CoV-2 Omicron spike protein (S-6P-RRAR) in complex with human ACE2 ectodomain (two-RBD-up state) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ... Authors: Gao, G.F, Qi, J.X, Zhao, Z.N, Liu, S, Xie, Y.F. Deposit date: 2022-03-24 Release date: 2022-08-31 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Omicron SARS-CoV-2 mutations stabilize spike up-RBD conformation and lead to a non-RBM-binding monoclonal antibody escape Nat Commun, 13, 2022
7XCI	Cryo-EM structure of SARS-CoV-2 Omicron RBD in complex with human ACE2 ectodomain (local refinement) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ... Authors: Gao, G.F, Qi, J.X, Zhao, Z.N, Liu, S, Xie, Y.F. Deposit date: 2022-03-24 Release date: 2022-08-31 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Omicron SARS-CoV-2 mutations stabilize spike up-RBD conformation and lead to a non-RBM-binding monoclonal antibody escape Nat Commun, 13, 2022
7XCP	Cryo-EM structure of Omicron RBD complexed with ACE2 and 304 Fab Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of 304 Fab, ... Authors: Zhao, Z, Qi, J, Gao, F.G. Deposit date: 2022-03-24 Release date: 2022-08-31 Method: ELECTRON MICROSCOPY (3.05 Å) Cite: Omicron SARS-CoV-2 mutations stabilize spike up-RBD conformation and lead to a non-RBM-binding monoclonal antibody escape Nat Commun, 13, 2022
7XCO	Cryo-EM structure of SARS-CoV-2 Omicron spike protein (S-6P-RRAR) in complex with S309 fab Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S309 Fab heavy chain, ... Authors: Gao, G.F, Qi, J.X, Zhao, Z.N, Liu, S, Xie, Y.F. Deposit date: 2022-03-24 Release date: 2022-09-21 Method: ELECTRON MICROSCOPY (2.5 Å) Cite: Omicron SARS-CoV-2 mutations stabilize spike up-RBD conformation and lead to a non-RBM-binding monoclonal antibody escape Nat Commun, 13, 2022
8VH3	CH505.M5.G458Y CE2 Design SOSIP Descriptor: CH505.CE2 SOSIP gp120, CH505.CE2 SOSIP gp41 Authors: Henderson, R, Acharya, P. Deposit date: 2023-12-30 Release date: 2024-10-02 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Engineering immunogens that select for specific mutations in HIV broadly neutralizing antibodies To Be Published
7S1B	Crystal structure of Epstein-Barr virus glycoproteins gH/gL/gp42-peptide in complex with human neutralizing antibodies 769C2 and 770F7 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 769C2 Fab heavy chain, 769C2 Fab light chain, ... Authors: Chen, W.-H, Cohen, J.I, Kanekiyo, M, Joyce, M.G. Deposit date: 2021-09-02 Release date: 2022-11-09 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (3.03 Å) Cite: Epstein-Barr virus gH/gL has multiple sites of vulnerability for virus neutralization and fusion inhibition. Immunity, 55, 2022
7S07	Crystal structure of Epstein-Barr virus glycoprotein gH/gL/gp42-peptide in complex with human neutralizing antibodies 769B10 and 769C2 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 769B10 Fab heavy chain, 769B10 Fab light chain, ... Authors: Chen, W.-H, Kanekiyo, M, Cohen, J.I, Joyce, M.G. Deposit date: 2021-08-30 Release date: 2022-11-09 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (3.29 Å) Cite: Epstein-Barr virus gH/gL has multiple sites of vulnerability for virus neutralization and fusion inhibition. Immunity, 55, 2022
8TFN	Structure of anti-TCRvbeta6-5 antibody in complex with the cognate TCR Descriptor: Anti-TCRVb6-5 Fab heavy chain, Anti-TCRVb6-5 Fab light chain, TRAV12-3, ... Authors: Katragadda, M, Servatalab, R, Wirth, J. Deposit date: 2023-07-11 Release date: 2023-11-08 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (2.54 Å) Cite: Innate TCR beta-chain engagement drives human T cells toward distinct memory-like effector phenotypes with immunotherapeutic potentials. Sci Adv, 9, 2023
7M6D	Structure of the SARS-CoV-2 RBD in complex with neutralizing antibodies BG4-25 and CR3022 Descriptor: BG4-25 Fab Heavy Chain, BG4-25 Fab Light Chain, CR3022 Fab Heavy Chain, ... Authors: Barnes, C.O, Bjorkman, P.J. Deposit date: 2021-03-25 Release date: 2021-05-05 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (3.1 Å) Cite: B cell genomics behind cross-neutralization of SARS-CoV-2 variants and SARS-CoV. Cell, 184, 2021
7PA8	JC polyomavirus VP1 in complex with Fab 27C2 Descriptor: Fab 27C2 heavy chain, Fab 27C2 light chain, Major capsid protein VP1 Authors: Stroeh, L.J, Harprecht, C, Freytag, J, Stehle, T. Deposit date: 2021-07-29 Release date: 2023-02-08 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (3.15 Å) Cite: Structural characterization of human neutralizing antibodies against JC and BK polyomavirus To Be Published
7PAA	JC polyomavirus VP1 in complex with scFv 29B1 Descriptor: Major capsid protein VP1, scFv 29B1 Authors: Harprecht, C, Stroeh, L.J, Freytag, J, Stehle, T. Deposit date: 2021-07-29 Release date: 2023-02-08 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (3.102 Å) Cite: Structural characterization of human neutralizing antibodies against JC and BK polyomavirus To Be Published
7PA9	JC polyomavirus VP1 in complex with Fab 98D3 Descriptor: Fab 98D3 VH, Fab 98D3 VL, Major capsid protein VP1 Authors: Stroeh, L.J, Harprecht, C, Freytag, J, Stehle, T. Deposit date: 2021-07-29 Release date: 2023-02-08 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.75 Å) Cite: Structural characterization of human neutralizing antibodies against JC and BK polyomavirus To Be Published
7T17	Zika Virus asymmetric unit bound with IgM antibody DH1017 Fab fragment Descriptor: Core protein, DH1017.IgM FabC constant domain, DH1017.IgM IgH, ... Authors: Miller, A.S, Kuhn, R.J. Deposit date: 2021-12-01 Release date: 2022-11-23 Last modified: 2024-06-05 Method: ELECTRON MICROSCOPY (5.26 Å) Cite: A Zika virus-specific IgM elicited in pregnancy exhibits ultrapotent neutralization. Cell, 185, 2022
8PKC	Structure of Api m1 in complex with the AM1-4 nanobody Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, AM1-4 nanobody, Phospholipase A2 Authors: Aagaard, J.B, Gandini, R, Spillner, E, Miehe, M. Deposit date: 2023-06-26 Release date: 2024-05-08 Method: X-RAY DIFFRACTION (4.1 Å) Cite: Nanobody-based IgG formats as blocking antibodies of the major honeybee venom allergen Api m 1 To be published
8PIH	Structure of Api m1 in complex with two nanobodies Descriptor: CHLORIDE ION, Phospholipase A2, nanobdoy AM1-1, ... Authors: Aagaard, J.B, Gandini, R, Spillner, E, Miehe, M, Andersen, G.R. Deposit date: 2023-06-21 Release date: 2024-05-08 Method: X-RAY DIFFRACTION (1.76 Å) Cite: Nanobody-based IgG formats as blocking antibodies of the major honeybee venom allergen Api m 1 To be published
8PMX	rat HEV P domain in complex with glycan-sensitive nAb p60.12 Descriptor: Fab p60.12-HC, Fab p60.12-LC, Pro-secreted protein ORF2 Authors: Ssebyatika, G, Krey, T. Deposit date: 2023-06-29 Release date: 2024-07-10 Method: X-RAY DIFFRACTION (3.922 Å) Cite: A novel class of broadly neutralizing hepatitis E virus-specific human antibodies To Be Published
8PMW	HEV gt3 P domain in complex with glycan-sensitive nAb p60.1 Descriptor: ACETATE ION, Capsid protein, SULFATE ION, ... Authors: Ssebyatika, G, Krey, T. Deposit date: 2023-06-29 Release date: 2024-07-10 Method: X-RAY DIFFRACTION (1.98 Å) Cite: A novel class of broadly neutralizing hepatitis E virus-specific human antibodies To Be Published

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