3R69
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![BU of 3r69 by Molmil](/molmil-images/mine/3r69) | Molecular analysis of the interaction of the HDL-receptor SR-BI with the PDZ3 domain of its adaptor protein PDZK1 | Descriptor: | CITRIC ACID, Na(+)/H(+) exchange regulatory cofactor NHE-RF3, Scavenger receptor class B member 1 | Authors: | Kocher, O, Birrane, G, Krieger, M. | Deposit date: | 2011-03-21 | Release date: | 2011-05-18 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.499 Å) | Cite: | Identification of the PDZ3 Domain of the Adaptor Protein PDZK1 as a Second, Physiologically Functional Binding Site for the C Terminus of the High Density Lipoprotein Receptor Scavenger Receptor Class B Type I. J.Biol.Chem., 286, 2011
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1Y71
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![BU of 1y71 by Molmil](/molmil-images/mine/1y71) | X-ray crystal structure of kinase-associated protein B from Bacillus cereus | Descriptor: | Kinase-associated protein B | Authors: | Osipiuk, J, Zhou, M, Moy, S, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2004-12-07 | Release date: | 2005-01-18 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | X-ray crystal structure of kinase-associated protein B from Bacillus cereus To be Published
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4AM6
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![BU of 4am6 by Molmil](/molmil-images/mine/4am6) | C-TERMINAL DOMAIN OF ACTIN-RELATED PROTEIN ARP8 FROM S. CEREVISIAE | Descriptor: | ACTIN-LIKE PROTEIN ARP8, SULFATE ION | Authors: | Wuerges, J, Saravanan, M, Bose, D, Cook, N.J, Zhang, X, Wigley, D.B. | Deposit date: | 2012-03-07 | Release date: | 2012-12-12 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Interactions between the Nucleosome Histone Core and Arp8 in the Ino80 Chromatin Remodeling Complex. Proc.Natl.Acad.Sci.USA, 109, 2012
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1CG9
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![BU of 1cg9 by Molmil](/molmil-images/mine/1cg9) | COMPLEX RECOGNITION OF THE SUPERTYPIC BW6-DETERMINANT ON HLA-B AND-C MOLECULES BY THE MONOCLONAL ANTIBODY SFR8-B6 | Descriptor: | PROTEIN (BETA-2-MICROGLOBULIN), PROTEIN (EBNA-6 NUCLEAR PROTEIN (EBNA-3C) (EBNA-4B)), PROTEIN (HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ... | Authors: | Menssen, R, Orth, P, Ziegler, A, Saenger, W. | Deposit date: | 1999-03-25 | Release date: | 2003-11-18 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Complex Recognition of the Supertypic Bw6-Determinant on HLA-B and-C Molecules
by the Monoclonal Antibody SFR8-B6 To be Published
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4IBA
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![BU of 4iba by Molmil](/molmil-images/mine/4iba) | Bovine beta-lactoglobulin (isoform B) in complex with dodecyl sulphate (SDS) | Descriptor: | DODECYL SULFATE, GLYCEROL, beta-lactoglobulin | Authors: | Loch, J.I, Bonarek, P, Polit, A, Swiatek, S, Dziedzicka-Wasylewska, M, Lewinski, K. | Deposit date: | 2012-12-08 | Release date: | 2013-06-26 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The differences in binding 12-carbon aliphatic ligands by bovine beta-lactoglobulin isoform A and B studied by isothermal titration calorimetry and X-ray crystallography J.Mol.Recognit., 26, 2013
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4QTI
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![BU of 4qti by Molmil](/molmil-images/mine/4qti) | Crystal structure of human uPAR in complex with anti-uPAR Fab 8B12 | Descriptor: | Urokinase plasminogen activator surface receptor, anti-uPAR antibody, heavy chain, ... | Authors: | Zhao, B, Yuan, C, Luo, Z, Huang, M. | Deposit date: | 2014-07-08 | Release date: | 2015-02-25 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Stabilizing a flexible interdomain hinge region harboring the SMB binding site drives uPAR into its closed conformation. J.Mol.Biol., 427, 2015
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1AJ6
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![BU of 1aj6 by Molmil](/molmil-images/mine/1aj6) | |
3QIO
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![BU of 3qio by Molmil](/molmil-images/mine/3qio) | Crystal Structure of HIV-1 RNase H with engineered E. coli loop and N-hydroxy quinazolinedione inhibitor | Descriptor: | 3-hydroxy-6-(phenylsulfonyl)quinazoline-2,4(1H,3H)-dione, Gag-Pol polyprotein,Ribonuclease HI,Gag-Pol polyprotein, MANGANESE (II) ION, ... | Authors: | Lansdon, E.B, Liu, Q. | Deposit date: | 2011-01-27 | Release date: | 2011-04-20 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.4011 Å) | Cite: | Structural and Binding Analysis of Pyrimidinol Carboxylic Acid and N-Hydroxy Quinazolinedione HIV-1 RNase H Inhibitors. Antimicrob.Agents Chemother., 55, 2011
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7LGL
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![BU of 7lgl by Molmil](/molmil-images/mine/7lgl) | |
3I0O
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![BU of 3i0o by Molmil](/molmil-images/mine/3i0o) | Crystal Structure of Spectinomycin Phosphotransferase, APH(9)-Ia, in complex with ADP and Spectinomcyin | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, NICKEL (II) ION, ... | Authors: | Fong, D.H, Lemke, C.T, Hwang, J, Xiong, B, Berghuis, A.M. | Deposit date: | 2009-06-25 | Release date: | 2010-01-19 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure of the antibiotic resistance factor spectinomycin phosphotransferase from Legionella pneumophila. J.Biol.Chem., 285, 2010
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4G87
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![BU of 4g87 by Molmil](/molmil-images/mine/4g87) | Crystal structure of GLMU from Mycobacterium tuberculosis snapshot 1 | Descriptor: | Bifunctional protein GlmU, COBALT (II) ION, MAGNESIUM ION, ... | Authors: | Jagtap, P.A, Verma, S.K, Prakash, B. | Deposit date: | 2012-07-22 | Release date: | 2013-03-13 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Crystal structures identify an atypical two-metal-ion mechanism for uridyltransfer in GlmU: its significance to sugar nucleotidyl transferases J.Mol.Biol., 425, 2013
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1XFB
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![BU of 1xfb by Molmil](/molmil-images/mine/1xfb) | Human Brain Fructose 1,6-(bis)phosphate Aldolase (C isozyme) | Descriptor: | Aldolase C | Authors: | Arakaki, T.L, Pezza, J.A, Cronin, M.A, Hopkins, C.E, Zimmer, D.B, Tolan, D.R, Allen, K.N. | Deposit date: | 2004-09-14 | Release date: | 2005-02-08 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structure of human brain fructose 1,6-(bis)phosphate aldolase: linking isozyme structure with function Protein Sci., 13, 2004
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4ION
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![BU of 4ion by Molmil](/molmil-images/mine/4ion) | Macrolepiota procera ricin B-like lectin (MPL) | Descriptor: | GLYCEROL, Ricin B-like lectin | Authors: | Renko, M, Zurga, S, Sabotic, J, Pohleven, J, Kos, J, Turk, D. | Deposit date: | 2013-01-08 | Release date: | 2013-11-20 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Macrolepiota procera ricin B-like lectin (MPL) TO BE PUBLISHED
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4HPO
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![BU of 4hpo by Molmil](/molmil-images/mine/4hpo) | Crystal structure of RV144-elicited antibody CH58 in complex with V2 peptide | Descriptor: | CH58 Fab heavy chain, CH58 Fab light chain, Envelope glycoprotein gp160, ... | Authors: | McLellan, J.S, Gorman, J, Haynes, B.F, Kwong, P.D. | Deposit date: | 2012-10-24 | Release date: | 2013-02-06 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.694 Å) | Cite: | Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2. Immunity, 38, 2013
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2I21
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![BU of 2i21 by Molmil](/molmil-images/mine/2i21) | Bacteriorhodopsin/lipid complex, T46V mutant | Descriptor: | 1-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL, 2,10,23-TRIMETHYL-TETRACOSANE, Bacteriorhodopsin, ... | Authors: | Lanyi, J.K, Schobert, B. | Deposit date: | 2006-08-15 | Release date: | 2006-10-10 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | Propagating Structural Perturbation Inside Bacteriorhodopsin: Crystal Structures of the M State and the D96A and T46V Mutants. Biochemistry, 45, 2006
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3SZ6
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![BU of 3sz6 by Molmil](/molmil-images/mine/3sz6) | IsdX1, an anthrax hemophore | Descriptor: | CHLORIDE ION, Conserved domain protein, GLYCEROL | Authors: | Poor, C.B, Maresso, A.W, Murphy, F, He, C. | Deposit date: | 2011-07-18 | Release date: | 2012-03-28 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Differential function of lip residues in the mechanism and biology of an anthrax hemophore. Plos Pathog., 8, 2012
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2KJQ
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![BU of 2kjq by Molmil](/molmil-images/mine/2kjq) | Solution Structure Of Protein NMB1076 From Neisseria meningitidis. Northeast Structural Genomics Consortium Target MR101B. | Descriptor: | DnaA-related protein | Authors: | Wu, Y, Maglaqui, M, Eletsky, A, Ciccosanti, C, Sathyamoorthy, B, Jiang, M, Garcia, E, Nair, R, Rost, B, Swapna, G, Acton, T, Xiao, R, Everett, J, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2009-06-08 | Release date: | 2010-04-28 | Last modified: | 2024-05-08 | Method: | SOLUTION NMR | Cite: | Solution Structure Of Protein NMB1076 From Neisseria meningitidis. Northeast Structural Genomics Consortium Target MR101B. To be Published
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3GNW
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![BU of 3gnw by Molmil](/molmil-images/mine/3gnw) | HCV NS5B polymerase in complex with 1,5 benzodiazepine inhibitor 4c | Descriptor: | (11S)-11-[4-(benzyloxy)-2-fluorophenyl]-3,3-dimethyl-10-[(6-methylpyridin-2-yl)carbonyl]-2,3,4,5,10,11-hexahydrothiopyrano[3,2-b][1,5]benzodiazepin-6-ol 1,1-dioxide, CHLORIDE ION, RNA-directed RNA polymerase | Authors: | Nyanguile, O, De Bondt, H. | Deposit date: | 2009-03-18 | Release date: | 2009-10-20 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.39 Å) | Cite: | Structure-based design of a benzodiazepine scaffold yields a potent allosteric inhibitor of hepatitis C NS5B RNA polymerase. J.Med.Chem., 52, 2009
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3GV2
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![BU of 3gv2 by Molmil](/molmil-images/mine/3gv2) | X-ray Structure of Hexameric HIV-1 CA | Descriptor: | Capsid protein p24,Carbon dioxide-concentrating mechanism protein CcmK homolog 4 | Authors: | Kelly, B.N. | Deposit date: | 2009-03-30 | Release date: | 2009-06-23 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (7 Å) | Cite: | X-ray structures of the hexameric building block of the HIV capsid. Cell(Cambridge,Mass.), 137, 2009
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3I5N
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![BU of 3i5n by Molmil](/molmil-images/mine/3i5n) | Crystal structure of c-Met with triazolopyridazine inhibitor 13 | Descriptor: | 7-methoxy-N-[(6-phenyl[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methyl]-1,5-naphthyridin-4-amine, Hepatocyte growth factor receptor | Authors: | Bellon, S.F, Whittington, D.A, Long, A.M, Boezio, A.A. | Deposit date: | 2009-07-06 | Release date: | 2010-01-12 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Discovery and optimization of potent and selective triazolopyridazine series of c-Met inhibitors Bioorg.Med.Chem.Lett., 19, 2009
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1ZIZ
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![BU of 1ziz by Molmil](/molmil-images/mine/1ziz) | Crystal Structure of Human Galactosyltransferase (GTB) Complexed with Galactose | Descriptor: | ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase), ... | Authors: | Letts, J.A, Rose, N.L, Fang, Y.R, Barry, C.H, Borisova, S.N, Seto, N.O, Palcic, M.M, Evans, S.V. | Deposit date: | 2005-04-27 | Release date: | 2005-12-13 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.49 Å) | Cite: | Differential Recognition of the Type I and II H Antigen Acceptors by the Human ABO(H) Blood Group A and B Glycosyltransferases. J.Biol.Chem., 281, 2006
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4S1Q
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![BU of 4s1q by Molmil](/molmil-images/mine/4s1q) | Crystal structure of a VRC01-lineage antibody, 45-VRC01.H03+06.D-001739, in complex with clade A/E HIV-1 gp120 core | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab of VRC01 light chain, Fab of VRC01-lineage antibody,45-VRC01.H03+06.D-001739 heavy chain, ... | Authors: | Kwon, Y.D, Yang, Y, Zhang, B, Kwong, P.D. | Deposit date: | 2015-01-14 | Release date: | 2015-04-22 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection. Cell(Cambridge,Mass.), 161, 2015
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1US0
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![BU of 1us0 by Molmil](/molmil-images/mine/1us0) | Human Aldose Reductase in complex with NADP+ and the inhibitor IDD594 at 0.66 Angstrom | Descriptor: | ALDOSE REDUCTASE, CITRIC ACID, IDD594, ... | Authors: | Howard, E.I, Sanishvili, R, Cachau, R.E, Mitschler, A, Chevrier, B, Barth, P, Lamour, V, Van Zandt, M, Sibley, E, Bon, C, Moras, D, Schneider, T.R, Joachimiak, A, Podjarny, A. | Deposit date: | 2003-11-16 | Release date: | 2004-05-07 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (0.66 Å) | Cite: | Ultrahigh Resolution Drug Design I: Details of Interactions in Human Aldose Reductase-Inhibitor Complex at 0.66 A. Proteins, 55, 2004
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3Q6E
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![BU of 3q6e by Molmil](/molmil-images/mine/3q6e) | Human insulin in complex with cucurbit[7]uril | Descriptor: | Insulin A chain, Insulin B chain, cucurbit[7]uril | Authors: | Chinai, J.M, Taylor, A.B, Hargreaves, N.D, Ryno, L.M, Morris, C.A, Hart, P.J, Urbach, A.R. | Deposit date: | 2010-12-31 | Release date: | 2011-04-20 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Molecular recognition of insulin by a synthetic receptor. J.Am.Chem.Soc., 133, 2011
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3QD6
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![BU of 3qd6 by Molmil](/molmil-images/mine/3qd6) | Crystal structure of the CD40 and CD154 (CD40L) complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CD40 ligand, Tumor necrosis factor receptor superfamily member 5 | Authors: | Lee, J.-O, Kim, Y.J, Song, D.H, Kim, H.M, Park, B.S. | Deposit date: | 2011-01-18 | Release date: | 2011-02-02 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Crystallographic and mutational analysis of the CD40-CD154 complex and its implications for receptor activation J.Biol.Chem., 286, 2011
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