2NZ0
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![BU of 2nz0 by Molmil](/molmil-images/mine/2nz0) | Crystal structure of potassium channel Kv4.3 in complex with its regulatory subunit KChIP1 | Descriptor: | CALCIUM ION, Kv channel-interacting protein 1, Potassium voltage-gated channel subfamily D member 3, ... | Authors: | Wang, H, Yan, Y, Shen, Y, Chen, L, Wang, K. | Deposit date: | 2006-11-22 | Release date: | 2006-12-26 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural basis for modulation of Kv4 K(+) channels by auxiliary KChIP subunits. Nat.Neurosci., 10, 2007
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2MDI
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![BU of 2mdi by Molmil](/molmil-images/mine/2mdi) | Solution structure of the PP2WW mutant (KPP2WW) of HYPB | Descriptor: | Histone-lysine N-methyltransferase SETD2 | Authors: | Gao, Y.G, Hu, H.Y. | Deposit date: | 2013-09-10 | Release date: | 2014-09-10 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Autoinhibitory structure of the WW domain of HYPB/SETD2 regulates its interaction with the proline-rich region of huntingtin. Structure, 22, 2014
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2LXL
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![BU of 2lxl by Molmil](/molmil-images/mine/2lxl) | Lip5(mit)2 | Descriptor: | Vacuolar protein sorting-associated protein VTA1 homolog | Authors: | Skalicky, J.J, Sundquist, W.I. | Deposit date: | 2012-08-29 | Release date: | 2012-11-28 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Interactions of the Human LIP5 Regulatory Protein with Endosomal Sorting Complexes Required for Transport. J.Biol.Chem., 287, 2012
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3ZFW
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![BU of 3zfw by Molmil](/molmil-images/mine/3zfw) | Crystal structure of the TPR domain of kinesin light chain 2 in complex with a tryptophan-acidic cargo peptide | Descriptor: | KINESIN LIGHT CHAIN 2, PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY M MEMBER 2 | Authors: | Pernigo, S, Lamprecht, A, Steiner, R.A, Dodding, M.P. | Deposit date: | 2012-12-12 | Release date: | 2013-04-03 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural Basis for Kinesin-1:Cargo Recognition. Science, 340, 2013
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3AKG
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![BU of 3akg by Molmil](/molmil-images/mine/3akg) | Crystal structure of exo-1,5-alpha-L-arabinofuranosidase complexed with alpha-1,5-L-arabinofuranobiose | Descriptor: | CHLORIDE ION, GLYCEROL, Putative secreted alpha L-arabinofuranosidase II, ... | Authors: | Fujimoto, Z, Ichinose, H, Kaneko, S. | Deposit date: | 2010-07-14 | Release date: | 2010-08-25 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal Structure of an Exo-1,5-{alpha}-L-arabinofuranosidase from Streptomyces avermitilis Provides Insights into the Mechanism of Substrate Discrimination between Exo- and Endo-type Enzymes in Glycoside Hydrolase Family 43. J.Biol.Chem., 285, 2010
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3AKI
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![BU of 3aki by Molmil](/molmil-images/mine/3aki) | Crystal structure of exo-1,5-alpha-L-arabinofuranosidase complexed with alpha-L-arabinofuranosyl azido | Descriptor: | (2R,3R,4R,5S)-2-azido-5-(hydroxymethyl)oxolane-3,4-diol, CHLORIDE ION, GLYCEROL, ... | Authors: | Fujimoto, Z, Ichinose, H, Kaneko, S. | Deposit date: | 2010-07-14 | Release date: | 2010-08-25 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of an Exo-1,5-{alpha}-L-arabinofuranosidase from Streptomyces avermitilis Provides Insights into the Mechanism of Substrate Discrimination between Exo- and Endo-type Enzymes in Glycoside Hydrolase Family 43. J.Biol.Chem., 285, 2010
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3AKH
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![BU of 3akh by Molmil](/molmil-images/mine/3akh) | Crystal structure of exo-1,5-alpha-L-arabinofuranosidase complexed with alpha-1,5-L-arabinofuranotriose | Descriptor: | CHLORIDE ION, GLYCEROL, Putative secreted alpha L-arabinofuranosidase II, ... | Authors: | Fujimoto, Z, Ichinose, H, Kaneko, S. | Deposit date: | 2010-07-14 | Release date: | 2010-08-25 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal Structure of an Exo-1,5-{alpha}-L-arabinofuranosidase from Streptomyces avermitilis Provides Insights into the Mechanism of Substrate Discrimination between Exo- and Endo-type Enzymes in Glycoside Hydrolase Family 43. J.Biol.Chem., 285, 2010
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2N1O
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3AKF
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![BU of 3akf by Molmil](/molmil-images/mine/3akf) | Crystal structure of exo-1,5-alpha-L-arabinofuranosidase | Descriptor: | CHLORIDE ION, GLYCEROL, Putative secreted alpha L-arabinofuranosidase II, ... | Authors: | Fujimoto, Z, Ichinose, H, Kaneko, S. | Deposit date: | 2010-07-14 | Release date: | 2010-08-25 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal Structure of an Exo-1,5-{alpha}-L-arabinofuranosidase from Streptomyces avermitilis Provides Insights into the Mechanism of Substrate Discrimination between Exo- and Endo-type Enzymes in Glycoside Hydrolase Family 43. J.Biol.Chem., 285, 2010
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3F0M
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![BU of 3f0m by Molmil](/molmil-images/mine/3f0m) | Crystal structure of radical D105N Synechocystis sp. PcyA | Descriptor: | 1,2-ETHANEDIOL, BILIVERDINE IX ALPHA, Phycocyanobilin:ferredoxin oxidoreductase | Authors: | Kohler, A.C, Gae, D.D. | Deposit date: | 2008-10-25 | Release date: | 2009-10-13 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural basis for hydration dynamics in radical stabilization of bilin reductase mutants. Biochemistry, 49, 2010
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3F0L
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![BU of 3f0l by Molmil](/molmil-images/mine/3f0l) | Crystal structure of oxidized D105N Synechocystis sp. PcyA | Descriptor: | 1,2-ETHANEDIOL, BILIVERDINE IX ALPHA, Phycocyanobilin:ferredoxin oxidoreductase | Authors: | Kohler, A.C, Gae, D.D. | Deposit date: | 2008-10-25 | Release date: | 2009-10-13 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Structural basis for hydration dynamics in radical stabilization of bilin reductase mutants. Biochemistry, 49, 2010
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6OBA
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![BU of 6oba by Molmil](/molmil-images/mine/6oba) | The beta2 adrenergic receptor bound to a negative allosteric modulator | Descriptor: | (2S)-1-[(1-methylethyl)amino]-3-(2-prop-2-en-1-ylphenoxy)propan-2-ol, 6-bromo-N~2~-phenylquinazoline-2,4-diamine, Beta-2 adrenergic receptor,Lysozyme,Beta-2 adrenergic receptor, ... | Authors: | Liu, X, Stobel, A, Kaindl, J, Dengler, D, ClarK, M, Mahoney, J, Korczynska, M, Matt, R.A, Hubner, H, Xu, X, Stanek, M, Hirata, K, Shoichet, B, Sunahara, R, Gmeiner, R, Kobilka, B.K. | Deposit date: | 2019-03-20 | Release date: | 2020-03-25 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | An allosteric modulator binds to a conformational hub in the beta2adrenergic receptor. Nat.Chem.Biol., 16, 2020
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8RPP
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![BU of 8rpp by Molmil](/molmil-images/mine/8rpp) | |
6EUJ
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![BU of 6euj by Molmil](/molmil-images/mine/6euj) | The GH43, Beta 1,3 Galactosidase, BT0265 | Descriptor: | Beta-glucanase | Authors: | Cartmell, A, Gilbert, H.J. | Deposit date: | 2017-10-30 | Release date: | 2018-10-17 | Last modified: | 2019-10-16 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | A surface endogalactanase in Bacteroides thetaiotaomicron confers keystone status for arabinogalactan degradation. Nat Microbiol, 3, 2018
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6EUF
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![BU of 6euf by Molmil](/molmil-images/mine/6euf) | The GH43, Beta 1,3 Galactosidase, BT0265 | Descriptor: | Beta-glucanase, alpha-L-arabinofuranose-(1-3)-[alpha-L-arabinofuranose-(1-4)][beta-D-glucopyranuronic acid-(1-6)]beta-D-galactopyranose-(1-6)-beta-D-galactopyranose, alpha-L-rhamnopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-6)-[alpha-L-arabinofuranose-(1-3)][alpha-L-arabinofuranose-(1-4)]beta-D-galactopyranose-(1-6)-beta-D-galactopyranose | Authors: | Cartmell, A, Gilbert, H.J. | Deposit date: | 2017-10-30 | Release date: | 2018-10-17 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | A surface endogalactanase in Bacteroides thetaiotaomicron confers keystone status for arabinogalactan degradation. Nat Microbiol, 3, 2018
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6QB8
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![BU of 6qb8 by Molmil](/molmil-images/mine/6qb8) | Human CCT:mLST8 complex | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, ... | Authors: | Cuellar, J, Santiago, C, Ludlam, W.G, Bueno-Carrasco, M.T, Valpuesta, J.M, Willardson, B.M. | Deposit date: | 2018-12-20 | Release date: | 2019-07-03 | Last modified: | 2022-03-30 | Method: | ELECTRON MICROSCOPY (3.97 Å) | Cite: | Structural and functional analysis of the role of the chaperonin CCT in mTOR complex assembly. Nat Commun, 10, 2019
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4RSE
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![BU of 4rse by Molmil](/molmil-images/mine/4rse) | Crystal structure of RPE65 in complex with MB-001 and palmitate | Descriptor: | (1R)-3-amino-1-{3-[(2,6,6-trimethylcyclohex-1-en-1-yl)methoxy]phenyl}propan-1-ol, FE (II) ION, PALMITIC ACID, ... | Authors: | Kiser, P.D, Shi, W, Palczewski, K. | Deposit date: | 2014-11-07 | Release date: | 2015-04-15 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.39 Å) | Cite: | Catalytic mechanism of a retinoid isomerase essential for vertebrate vision. Nat.Chem.Biol., 11, 2015
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4A8A
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![BU of 4a8a by Molmil](/molmil-images/mine/4a8a) | Asymmetric cryo-EM reconstruction of E. coli DegQ 12-mer in complex with lysozyme | Descriptor: | LYSOZYME C, PERIPLASMIC PH-DEPENDENT SERINE ENDOPROTEASE DEGQ | Authors: | Malet, H, Canellas, F, Sawa, J, Yan, J, Thalassinos, K, Ehrmann, M, Clausen, T, Saibil, H.R. | Deposit date: | 2011-11-20 | Release date: | 2011-12-28 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (14.2 Å) | Cite: | Newly Folded Substrates Inside the Molecular Cage of the Htra Chaperone Degq Nat.Struct.Mol.Biol., 19, 2012
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5IKQ
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![BU of 5ikq by Molmil](/molmil-images/mine/5ikq) | The Structure of Meclofenamic Acid Bound to Human Cyclooxygenase-2 | Descriptor: | 2-[(2,6-dichloro-3-methyl-phenyl)amino]benzoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACRYLIC ACID, ... | Authors: | Orlando, B.J, Malkowski, M.G. | Deposit date: | 2016-03-03 | Release date: | 2016-05-25 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | Substrate-selective Inhibition of Cyclooxygeanse-2 by Fenamic Acid Derivatives Is Dependent on Peroxide Tone. J.Biol.Chem., 291, 2016
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4OQS
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![BU of 4oqs by Molmil](/molmil-images/mine/4oqs) | Crystal structure of CYP105AS1 | Descriptor: | CYP105AS1, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Leys, D. | Deposit date: | 2014-02-10 | Release date: | 2015-02-18 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | Single-step fermentative production of the cholesterol-lowering drug pravastatin via reprogramming of Penicillium chrysogenum. Proc.Natl.Acad.Sci.USA, 112, 2015
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6EG1
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![BU of 6eg1 by Molmil](/molmil-images/mine/6eg1) | Crystal structure of Dpr2 Ig1-Ig2 in complex with DIP-Theta Ig1-Ig3 | Descriptor: | (R,R)-2,3-BUTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Cosmanescu, F, Patel, S, Shapiro, L. | Deposit date: | 2018-08-17 | Release date: | 2018-11-28 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Neuron-Subtype-Specific Expression, Interaction Affinities, and Specificity Determinants of DIP/Dpr Cell Recognition Proteins. Neuron, 100, 2018
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5IDI
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![BU of 5idi by Molmil](/molmil-images/mine/5idi) | Structure of beta glucosidase 1A from Thermotoga neapolitana, mutant E349A | Descriptor: | 1,4-beta-D-glucan glucohydrolase, ACETATE ION | Authors: | Kulkarni, T, Nordberg Karlsson, E, Logan, D.T. | Deposit date: | 2016-02-24 | Release date: | 2017-02-08 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of beta-glucosidase 1A from Thermotoga neapolitana and comparison of active site mutants for hydrolysis of flavonoid glucosides. Proteins, 85, 2017
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5IKR
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![BU of 5ikr by Molmil](/molmil-images/mine/5ikr) | The Structure of Mefenamic Acid Bound to Human Cyclooxygenase-2 | Descriptor: | 2-[(2,3-DIMETHYLPHENYL)AMINO]BENZOIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, AMMONIUM ION, ... | Authors: | Orlando, B.J, Malkowski, M.G. | Deposit date: | 2016-03-03 | Release date: | 2016-05-25 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.342 Å) | Cite: | Substrate-selective Inhibition of Cyclooxygeanse-2 by Fenamic Acid Derivatives Is Dependent on Peroxide Tone. J.Biol.Chem., 291, 2016
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6EFZ
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![BU of 6efz by Molmil](/molmil-images/mine/6efz) | Crystal Structure of DIP-Theta Ig1-3 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Cosmanescu, F, Shapiro, L. | Deposit date: | 2018-08-17 | Release date: | 2018-11-28 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.499 Å) | Cite: | Neuron-Subtype-Specific Expression, Interaction Affinities, and Specificity Determinants of DIP/Dpr Cell Recognition Proteins. Neuron, 100, 2018
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6ERF
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![BU of 6erf by Molmil](/molmil-images/mine/6erf) | Complex of APLF factor and Ku heterodimer bound to DNA | Descriptor: | Aprataxin and PNK-like factor, DNA (34-MER), DNA (5'-D(*GP*TP*TP*TP*TP*TP*AP*GP*TP*TP*TP*AP*TP*TP*GP*GP*GP*CP*GP*CP*G)-3'), ... | Authors: | Nemoz, C, Legrand, P, Ropars, V, Charbonnier, J.B. | Deposit date: | 2017-10-18 | Release date: | 2018-10-17 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.01 Å) | Cite: | XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining. Nat.Struct.Mol.Biol., 25, 2018
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