2MDI

Solution structure of the PP2WW mutant (KPP2WW) of HYPB

Summary for 2MDI

• Entry DOI: 10.2210/pdb2mdi/pdb
• Related: 2MDC
• NMR Information: BMRB: 19487
• Descriptor: Histone-lysine N-methyltransferase SETD2 (1 entity in total)
• Functional Keywords: ww domain, hypb, transferase
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus (Probable): Q9BYW2
• Total number of polymer chains: 1
• Total formula weight: 6193.77

Authors

Gao, Y.G.,Hu, H.Y. (deposition date: 2013-09-10, release date: 2014-09-10, Last modification date: 2023-06-14)

• Primary citation: Gao, Y.G.,Yang, H.,Zhao, J.,Jiang, Y.J.,Hu, H.Y.; Autoinhibitory structure of the WW domain of HYPB/SETD2 regulates its interaction with the proline-rich region of huntingtin.; Structure, 22:378-386, 2014; PubMed: 24412394; DOI: 10.1016/j.str.2013.12.005

Experimental method

SOLUTION NMR