2MDI
Solution structure of the PP2WW mutant (KPP2WW) of HYPB
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Histone-lysine N-methyltransferase SETD2 | polymer | 56 | 6193.8 | 1 | UniProt (Q9BYW2) Pfam (PF00397) | Homo sapiens (human) | HIF-1, Huntingtin yeast partner B, Huntingtin-interacting protein 1, HIP-1, Huntingtin-interacting protein B, Lysine N-methyltransferase 3A, SET domain-containing protein 2, hSET2, p231HBP |
Sequence modifications
A: 3 - 56 (UniProt: Q9BYW2)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | expression tag |
| Ser 2 | - | expression tag |
| Ala 11 | Lys 2385 | engineered mutation |
| Ala 12 | Pro 2386 | engineered mutation |
| Ala 13 | Lys 2387 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 6193.8 | |
| All* | Total formula weight | 6193.8 |
