8RPP

Crystal structure of the JIP1-JIP2-SH3 heterodimer and the JIP2-JIP2-SH3 homodimer

Summary for 8RPP

• Entry DOI: 10.2210/pdb8rpp/pdb
• Related: 7NYK
• Descriptor: C-Jun-amino-terminal kinase-interacting protein 2, C-Jun-amino-terminal kinase-interacting protein 1 (3 entities in total)
• Functional Keywords: regulation of jnk cascade, signaling protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 29535.69

Authors

Palencia, A.,Marino-Perez, L.,Ielasi, F.I.,Jensen, M.R. (deposition date: 2024-01-16, release date: 2024-07-10, Last modification date: 2024-07-31)

• Primary citation: Marino Perez, L.,Ielasi, F.S.,Lee, A.,Delaforge, E.,Juyoux, P.,Tengo, M.,Davis, R.J.,Palencia, A.,Jensen, M.R.; Structural basis of homodimerization of the JNK scaffold protein JIP2 and its heterodimerization with JIP1.; Structure, 2024; PubMed: 39013462; DOI: 10.1016/j.str.2024.06.010

Experimental method

X-RAY DIFFRACTION (1.867 Å)