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8RPP

Crystal structure of the JIP1-JIP2-SH3 heterodimer and the JIP2-JIP2-SH3 homodimer

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C
(A, B, C)
C-Jun-amino-terminal kinase-interacting protein 2polymer637413.23UniProt (Q13387)
Pfam (PF14604)
Homo sapiens (human)JIP-2,JNK-interacting protein 2,Islet-brain-2,IB-2,JNK MAP kinase scaffold protein 2,Mitogen-activated protein kinase 8-interacting protein 2
2D
(D)
C-Jun-amino-terminal kinase-interacting protein 1polymer617296.11UniProt (Q9UQF2)
Pfam (PF14604)
Homo sapiens (human)JIP-1,JNK-interacting protein 1,Islet-brain 1,IB-1,JNK MAP kinase scaffold protein 1,Mitogen-activated protein kinase 8-interacting protein 1
3E, F, G, H
(A, B, C, D)
waterwater18.0182Chemie (HOH)
Sequence modifications
A, B, C: 605 - 665 (UniProt: Q13387)
PDBExternal DatabaseDetails
Gly 603-expression tag
Arg 604-expression tag
D: 490 - 547 (UniProt: Q9UQF2)
PDBExternal DatabaseDetails
Gly 487-expression tag
His 488-expression tag
Met 489-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight29535.7
All*Total formula weight29535.7
*Water molecules are not included.

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PDB entries from 2024-11-13

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