2YBS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ybs by Molmil](/molmil-images/mine/2ybs) | |
2YBP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ybp by Molmil](/molmil-images/mine/2ybp) | JMJD2A COMPLEXED WITH R-2-HYDROXYGLUTARATE AND HISTONE H3K36me3 PEPTIDE (30-41) | Descriptor: | (2R)-2-hydroxypentanedioic acid, GLYCEROL, HISTONE H3.1T, ... | Authors: | Chowdhury, R, McDonough, M.A, Schofield, C.J. | Deposit date: | 2011-03-09 | Release date: | 2011-03-30 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases. EMBO Rep., 12, 2011
|
|
5IN1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5in1 by Molmil](/molmil-images/mine/5in1) | Crystal Structure of the MRG701 chromodomain | Descriptor: | 1,2-ETHANEDIOL, MRG701, SULFATE ION | Authors: | Huang, Y, Liu, Y. | Deposit date: | 2016-03-07 | Release date: | 2017-03-01 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structural studies on MRG701 chromodomain reveal a novel dimerization interface of MRG proteins in green plants Protein Cell, 7, 2016
|
|
4BD3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4bd3 by Molmil](/molmil-images/mine/4bd3) | |
6S01
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6s01 by Molmil](/molmil-images/mine/6s01) | Structure of LEDGF PWWP domain bound H3K36 methylated nucleosome | Descriptor: | Histone H2A, Histone H2B 1.1, Histone H3, ... | Authors: | Wang, H, Farnung, L, Dienemann, C, Cramer, P. | Deposit date: | 2019-06-13 | Release date: | 2019-12-18 | Last modified: | 2020-01-22 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structure of H3K36-methylated nucleosome-PWWP complex reveals multivalent cross-gyre binding. Nat.Struct.Mol.Biol., 27, 2020
|
|
4PL6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4pl6 by Molmil](/molmil-images/mine/4pl6) | |
4N4G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4n4g by Molmil](/molmil-images/mine/4n4g) | |
4N4I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4n4i by Molmil](/molmil-images/mine/4n4i) | Crystal structure of the Bromo-PWWP of the mouse zinc finger MYND-type containing 11 isoform alpha in complex with histone H3.3K36me3 | Descriptor: | DI(HYDROXYETHYL)ETHER, PHOSPHATE ION, Peptide from Histone H3.3, ... | Authors: | Li, Y, Ren, Y, Li, H. | Deposit date: | 2013-10-08 | Release date: | 2014-03-05 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.999 Å) | Cite: | ZMYND11 links histone H3.3K36me3 to transcription elongation and tumour suppression Nature, 508, 2014
|
|
4N4H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4n4h by Molmil](/molmil-images/mine/4n4h) | Crystal structure of the Bromo-PWWP of the mouse zinc finger MYND-type containing 11 isoform alpha in complex with histone H3.1K36me3 | Descriptor: | DI(HYDROXYETHYL)ETHER, PHOSPHATE ION, Peptide from Histone H3.1, ... | Authors: | Li, Y, Ren, Y, Li, H. | Deposit date: | 2013-10-08 | Release date: | 2014-03-05 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.302 Å) | Cite: | ZMYND11 links histone H3.3K36me3 to transcription elongation and tumour suppression Nature, 508, 2014
|
|
8JHO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8jho by Molmil](/molmil-images/mine/8jho) | |
7E29
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7e29 by Molmil](/molmil-images/mine/7e29) | Crystal Structure of Saccharomyces cerevisiae Ioc4 PWWP domain fused with MBP | Descriptor: | Maltose/maltodextrin-binding periplasmic protein,ISWI one complex protein 4, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | Authors: | Li, J, Smolle, M, Liang, H, Liu, Y. | Deposit date: | 2021-02-05 | Release date: | 2022-02-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.303 Å) | Cite: | H3K36 methylation and DNA-binding both promote Ioc4 recruitment and Isw1b remodeler function. Nucleic Acids Res., 50, 2022
|
|
8CBQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8cbq by Molmil](/molmil-images/mine/8cbq) | structure of LEDGF/p75 PWWP domain bound to the H3K36 trimethylated dinucleosome | Descriptor: | Histone H2A, Histone H2B 1.1, Histone H3, ... | Authors: | Koutna, E, Kouba, T, Novacek, J, Veverka, V. | Deposit date: | 2023-01-25 | Release date: | 2023-09-06 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Multivalency of nucleosome recognition by LEDGF. Nucleic Acids Res., 51, 2023
|
|
8CBN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8cbn by Molmil](/molmil-images/mine/8cbn) | structure of LEDGF/p75 PWWP domain bound to the H3K36 trimethylated dinucleosome | Descriptor: | Histone H2A, Histone H2B 1.1, Histone H3, ... | Authors: | Koutna, E, Kouba, T, Novacek, J, Veverka, V. | Deposit date: | 2023-01-25 | Release date: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (3.34 Å) | Cite: | Multivalency of nucleosome recognition by LEDGF. Nucleic Acids Res., 51, 2023
|
|
8IFG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ifg by Molmil](/molmil-images/mine/8ifg) | Cryo-EM structure of the Clr6S (Clr6-HDAC) complex from S. pombe | Descriptor: | Chromatin modification-related protein eaf3, Cph1, Cph2, ... | Authors: | Zhang, H.Q, Wang, X, Wang, Y.N, Liu, S.M, Zhang, Y, Xu, K, Ji, L.T, Kornberg, R.D. | Deposit date: | 2023-02-17 | Release date: | 2024-01-03 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Class I histone deacetylase complex: Structure and functional correlates. Proc Natl Acad Sci U S A, 120, 2023
|
|
2M16
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2m16 by Molmil](/molmil-images/mine/2m16) | P75/LEDGF PWWP Domain | Descriptor: | PC4 and SFRS1-interacting protein | Authors: | Crowe, B.L, Foster, M.P. | Deposit date: | 2012-11-18 | Release date: | 2013-02-27 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural basis for high-affinity binding of LEDGF PWWP to mononucleosomes. Nucleic Acids Res., 41, 2013
|
|
4HON
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4hon by Molmil](/molmil-images/mine/4hon) | |
8HY0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8hy0 by Molmil](/molmil-images/mine/8hy0) | |
8HXZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8hxz by Molmil](/molmil-images/mine/8hxz) | Cryo-EM structure of Eaf3 CHD in complex with nucleosome | Descriptor: | Chromatin modification-related protein EAF3, DNA (352-MER), Histone H2A, ... | Authors: | Cui, H, Wang, H. | Deposit date: | 2023-01-05 | Release date: | 2023-09-27 | Last modified: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structure of histone deacetylase complex Rpd3S bound to nucleosome. Nat.Struct.Mol.Biol., 30, 2023
|
|
8HXX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8hxx by Molmil](/molmil-images/mine/8hxx) | Cryo-EM structure of the histone deacetylase complex Rpd3S | Descriptor: | Chromatin modification-related protein EAF3, Histone H3, Histone deacetylase RPD3, ... | Authors: | Cui, H, Wang, H. | Deposit date: | 2023-01-05 | Release date: | 2023-09-27 | Last modified: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structure of histone deacetylase complex Rpd3S bound to nucleosome. Nat.Struct.Mol.Biol., 30, 2023
|
|
8HXY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8hxy by Molmil](/molmil-images/mine/8hxy) | |
4HOO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4hoo by Molmil](/molmil-images/mine/4hoo) | Crystal structure of human JMJD2D/KDM4D apoenzyme | Descriptor: | ACETATE ION, Lysine-specific demethylase 4D, NICKEL (II) ION, ... | Authors: | Krishnan, S, Trievel, R.C. | Deposit date: | 2012-10-22 | Release date: | 2012-11-21 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.495 Å) | Cite: | Structural and Functional Analysis of JMJD2D Reveals Molecular Basis for Site-Specific Demethylation among JMJD2 Demethylases. Structure, 21, 2013
|
|
4A7J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4a7j by Molmil](/molmil-images/mine/4a7j) | Symmetric Dimethylation of H3 Arginine 2 is a Novel Histone Mark that Supports Euchromatin Maintenance | Descriptor: | HISTONE H3.1T, WD REPEAT-CONTAINING PROTEIN 5 | Authors: | Migliori, V, Muller, J, Phalke, S, Low, D, Bezzi, M, ChuenMok, W, Gunaratne, J, Capasso, P, Bassi, C, Cecatiello, V, DeMarco, A, Blackstock, W, Kuznetsov, V, Amati, B, Mapelli, M, Guccione, E. | Deposit date: | 2011-11-14 | Release date: | 2012-01-11 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Symmetric Dimethylation of H3R2 is a Newly Identified Histone Mark that Supports Euchromatin Maintenance Nat.Struct.Mol.Biol., 19, 2012
|
|
4AI9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ai9 by Molmil](/molmil-images/mine/4ai9) | JMJD2A Complexed with Daminozide | Descriptor: | CHLORIDE ION, DAMINOZIDE, GLYCEROL, ... | Authors: | Chowdhury, R, Schofield, C.J. | Deposit date: | 2012-02-08 | Release date: | 2012-10-03 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Plant growth regulator daminozide is a selective inhibitor of human KDM2/7 histone demethylases. J. Med. Chem., 55, 2012
|
|
2YBK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ybk by Molmil](/molmil-images/mine/2ybk) | JMJD2A COMPLEXED WITH R-2-HYDROXYGLUTARATE | Descriptor: | (2R)-2-hydroxypentanedioic acid, CHLORIDE ION, LYSINE-SPECIFIC DEMETHYLASE 4A, ... | Authors: | Chowdhury, R, McDonough, M.A, Schofield, C.J. | Deposit date: | 2011-03-08 | Release date: | 2011-04-06 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases. EMBO Rep., 12, 2011
|
|
6WAT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6wat by Molmil](/molmil-images/mine/6wat) | complex structure of PHF1 | Descriptor: | Histone H3.1t peptide, PHD finger protein 1, UNKNOWN ATOM OR ION | Authors: | Dong, C, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Min, J.R, Structural Genomics Consortium (SGC) | Deposit date: | 2020-03-26 | Release date: | 2020-08-26 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural basis for histone variant H3tK27me3 recognition by PHF1 and PHF19. Elife, 9, 2020
|
|