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2P55
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BU of 2p55 by Molmil
X-ray structure of the human mitogen-activated protein kinase kinase 1 (MEK1) in a complex with ligand and MgATP
Descriptor: 2-[(4-ETHYNYL-2-FLUOROPHENYL)AMINO]-3,4-DIFLUORO-N-(2-HYDROXYETHOXY)BENZAMIDE, ADENOSINE-5'-TRIPHOSPHATE, Dual specificity mitogen-activated protein kinase kinase 1, ...
Authors:Ohren, J.F, Pavlovsky, A.G.
Deposit date:2007-03-14
Release date:2007-10-02
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:4-anilino-5-carboxamido-2-pyridone derivatives as noncompetitive inhibitors of mitogen-activated protein kinase kinase.
J.Med.Chem., 50, 2007
2P56
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BU of 2p56 by Molmil
Crystal structure of alpha-2,3-sialyltransferase from Campylobacter jejuni in apo form
Descriptor: 1,2-ETHANEDIOL, Alpha-2,3-sialyltransferase
Authors:Chiu, C.P, Lairson, L.L, Gilbert, M, Wakarchuk, W.W, Withers, S.G, Strynadka, N.C.
Deposit date:2007-03-14
Release date:2007-07-10
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Analysis of the alpha-2,3-Sialyltransferase Cst-I from Campylobacter jejuni in Apo and Substrate-Analogue Bound Forms.
Biochemistry, 46, 2007
2P57
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BU of 2p57 by Molmil
GAP domain of ZNF289, an ID1-regulated zinc finger protein
Descriptor: GTPase-activating protein ZNF289, UNKNOWN ATOM OR ION, ZINC ION
Authors:Tong, Y, Dimov, S, Shen, L, Zhu, H, Tempel, W, Landry, R, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC)
Deposit date:2007-03-14
Release date:2007-03-27
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:GAP domain of ZNF289, an ID1-regulated zinc finger protein
To be Published
2P58
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BU of 2p58 by Molmil
Structure of the Yersinia pestis Type III secretion system needle protein YscF in complex with its chaperones YscE/YscG
Descriptor: Putative type III secretion protein YscE, Putative type III secretion protein YscF, Putative type III secretion protein YscG
Authors:Sun, P, Austin, B.P, Tropea, J.E, Waugh, D.S.
Deposit date:2007-03-14
Release date:2008-03-04
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural characterization of the Yersinia pestis type III secretion system needle protein YscF in complex with its heterodimeric chaperone YscE/YscG.
J.Mol.Biol., 377, 2008
2P59
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BU of 2p59 by Molmil
Crystal Structure of Hepatitis C Virus NS3.4A protease
Descriptor: (2S,3AS,7AS)-1-[(2S)-2-{[(2S)-2-CYCLOHEXYL-2-({[(2R)-4-NITRO-2H-PYRROL-2-YL]CARBONYL}AMINO)ACETYL]AMINO}-3,3-DIMETHYLBUTANOYL]-N-{(1S)-1-[(1R)-2-(CYCLOPROPYLAMINO)-1-HYDROXY-2-OXOETHYL]BUTYL}OCTAHYDRO-1H-INDOLE-2-CARBOXAMIDE, NS3, peptide
Authors:Perni, R.B, Wei, Y.
Deposit date:2007-03-14
Release date:2008-02-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Inhibitors of hepatitis C virus NS3.4A protease. Effect of P4 capping groups on inhibitory potency and pharmacokinetics.
Bioorg.Med.Chem.Lett., 17, 2007
2P5B
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BU of 2p5b by Molmil
The complex structure of JMJD2A and trimethylated H3K36 peptide
Descriptor: FE (II) ION, Histone H3, JmjC domain-containing histone demethylation protein 3A, ...
Authors:Zhang, G, Chen, Z, Zang, J, Hong, X, Shi, Y.
Deposit date:2007-03-14
Release date:2007-06-12
Last modified:2013-11-27
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Structural basis of the recognition of a methylated histone tail by JMJD2A.
Proc.Natl.Acad.Sci.USA, 104, 2007
2P5C
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BU of 2p5c by Molmil
Crystal structure of PH0725 from Pyrococcus horikoshii OT3
Descriptor: GLYCEROL, S-ADENOSYL-L-HOMOCYSTEINE, diphthine synthase
Authors:Yamamoto, H, Taketa, M, Ono, N, Matsuura, Y, Kunishima, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-03-15
Release date:2007-09-18
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of PH0725 from Pyrococcus horikoshii OT3
To be Published
2P5D
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BU of 2p5d by Molmil
Crystal structure of MJECL36 from Methanocaldococcus jannaschii DSM 2661
Descriptor: UPF0310 protein MJECL36
Authors:Sugahara, M, Kunishima, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-03-15
Release date:2007-09-18
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of MJECL36 from Methanocaldococcus jannaschii DSM 2661
To be Published
2P5E
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BU of 2p5e by Molmil
Crystal Structures of High Affinity Human T-Cell Receptors Bound to pMHC Reveal Native Diagonal Binding Geometry
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Beta-2-microglobulin, Cancer/testis antigen 1B, ...
Authors:Sami, M, Rizkallah, P.J, Dunn, S, Li, Y, Moysey, R, Vuidepot, A, Baston, E, Todorov, P, Molloy, P, Gao, F, Boulter, J.M, Jakobsen, B.K.
Deposit date:2007-03-15
Release date:2007-09-25
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Crystal structures of high affinity human T-cell receptors bound to peptide major histocompatibility complex reveal native diagonal binding geometry
Protein Eng.Des.Sel., 20, 2007
2P5F
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BU of 2p5f by Molmil
Crystal structure of PH0725 from Pyrococcus horikoshii OT3
Descriptor: S-ADENOSYL-L-HOMOCYSTEINE, diphthine synthase
Authors:Sugahara, M, Yamamoto, H, Kageyama, Y, Taketa, M, Matsuura, Y, Kunishima, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-03-15
Release date:2007-09-18
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of PH0725 from Pyrococcus horikoshii OT3
To be Published
2P5G
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BU of 2p5g by Molmil
Crystal structure of RB69 gp43 in complex with DNA with dAMP opposite an abasic site analog in a 21mer template
Descriptor: DNA polymerase, Primer DNA, Template DNA
Authors:Zahn, K.E, Belrhali, H, Wallace, S.S, Doublie, S.
Deposit date:2007-03-15
Release date:2007-10-23
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Caught bending the a-rule: crystal structures of translesion DNA synthesis with a non-natural nucleotide.
Biochemistry, 46, 2007
2P5H
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BU of 2p5h by Molmil
sPLA2 inhibitor 9
Descriptor: pip9
Authors:Thwin, M.M, Satyanarayanajois, D.S, Nagarajarao, L.M, Sato, K, Gopalakrishnakone, P.P, Arjunan, P.
Deposit date:2007-03-15
Release date:2007-11-13
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Novel Peptide Inhibitors of Human Secretory Phospholipase A2 with Antiinflammatory Activity: Solution Structure and Molecular Modeling.
J.Med.Chem., 50, 2007
2P5I
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BU of 2p5i by Molmil
Crystal structure of protein BH3822 from Bacillus halodurans, a member of the biotin/lipoate A/B protein ligase family
Descriptor: BH3822 protein
Authors:Sugadev, R, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2007-03-15
Release date:2007-03-27
Last modified:2021-02-03
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Crystal structure of a hypothetical protein from Bacillus halodurans: Pfam-PF03099
To be Published
2P5J
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BU of 2p5j by Molmil
sPLA2 inhibitor pip 17
Descriptor: pip17
Authors:Thwin, M.M, Satyanarayanajois, D.S, Nagarajarao, L.M, Sato, K, Gopalakrishnakone, P.P, Arjunan, P.
Deposit date:2007-03-15
Release date:2007-11-13
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Novel Peptide Inhibitors of Human Secretory Phospholipase A2 with Antiinflammatory Activity: Solution Structure and Molecular Modeling.
J.Med.Chem., 50, 2007
2P5K
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BU of 2p5k by Molmil
Crystal structure of the N-terminal domain of AhrC
Descriptor: Arginine repressor
Authors:Garnett, J.A, Baumberg, S, Stockley, P.G, Phillips, S.E.V.
Deposit date:2007-03-15
Release date:2007-10-30
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1 Å)
Cite:A high-resolution structure of the DNA-binding domain of AhrC, the arginine repressor/activator protein from Bacillus subtilis.
Acta Crystallogr.,Sect.F, 63, 2007
2P5L
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BU of 2p5l by Molmil
Crystal structure of a dimer of N-terminal domains of AhrC in complex with an 18bp DNA operator site
Descriptor: Arginine repressor, DNA (5'-D(*DCP*DAP*DTP*DGP*DAP*DAP*DTP*DAP*DAP*DAP*DAP*DAP*DTP*DTP*DCP*DAP*DAP*DG)-3'), DNA (5'-D(*DCP*DTP*DTP*DGP*DAP*DAP*DTP*DTP*DTP*DTP*DTP*DAP*DTP*DTP*DCP*DAP*DTP*DG)-3'), ...
Authors:Garnett, J.A, Marincs, F, Baumberg, S, Stockley, P.G, Phillips, S.E.V.
Deposit date:2007-03-15
Release date:2008-03-11
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structure and function of the arginine repressor-operator complex from Bacillus subtilis.
J.Mol.Biol., 379, 2008
2P5M
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BU of 2p5m by Molmil
C-terminal domain hexamer of AhrC bound with L-arginine
Descriptor: ARGININE, Arginine repressor
Authors:Garnett, J.A, Baumberg, S, Stockley, P.G, Phillips, S.E.V.
Deposit date:2007-03-15
Release date:2007-10-30
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structure of the C-terminal effector-binding domain of AhrC bound to its corepressor L-arginine.
Acta Crystallogr.,Sect.F, 63, 2007
2P5N
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BU of 2p5n by Molmil
Crystal structure of mouse 17-alpha hydroxysteroid dehydrogenase in complex with coenzyme NADPH
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Aldo-keto reductase family 1, member C21, ...
Authors:El-Kabbani, O, Dhagat, U.
Deposit date:2007-03-15
Release date:2007-10-09
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of 3(17)alpha-hydroxysteroid dehydrogenase (AKR1C21) holoenzyme from an orthorhombic crystal form: an insight into the bifunctionality of the enzyme.
Acta Crystallogr.,Sect.F, 63, 2007
2P5O
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BU of 2p5o by Molmil
Crystal structure of RB69 GP43 in complex with DNA containing an abasic site analog
Descriptor: DNA polymerase, Primer DNA, Template DNA
Authors:Hogg, M, Wallace, S.S, Doublie, S.
Deposit date:2007-03-15
Release date:2007-04-03
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystallographic snapshots of a replicative DNA polymerase encountering an abasic site.
Embo J., 23, 2004
2P5P
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BU of 2p5p by Molmil
Crystal Structure Analysis of the West Nile virus envelope (E) protein domain III
Descriptor: Genome polyprotein
Authors:Gao, F, Yuan, F, Gao, G.F.
Deposit date:2007-03-16
Release date:2008-03-18
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structure Analysis of the West Nile virus envelope (E) protein domain III
To be Published
2P5Q
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BU of 2p5q by Molmil
Crystal structure of the poplar glutathione peroxidase 5 in the reduced form
Descriptor: ACETATE ION, CADMIUM ION, Glutathione peroxidase 5
Authors:Koh, C.S, Didierjean, C, Navrot, N, Panjikar, S, Mulliert, G, Rouhier, N, Jacquot, J.-P, Aubry, A, Shawkataly, O, Corbier, C.
Deposit date:2007-03-16
Release date:2007-07-24
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structures of a Poplar Thioredoxin Peroxidase that Exhibits the Structure of Glutathione Peroxidases: Insights into Redox-driven Conformational Changes.
J.Mol.Biol., 370, 2007
2P5R
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BU of 2p5r by Molmil
Crystal structure of the poplar glutathione peroxidase 5 in the oxidized form
Descriptor: CALCIUM ION, Glutathione peroxidase 5
Authors:Koh, C.S, Didierjean, C, Navrot, N, Panjikar, S, Mulliert, G, Rouhier, N, Jacquot, J.-P, Aubry, A, Shawkataly, O, Corbier, C.
Deposit date:2007-03-16
Release date:2007-07-24
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Crystal Structures of a Poplar Thioredoxin Peroxidase that Exhibits the Structure of Glutathione Peroxidases: Insights into Redox-driven Conformational Changes.
J.Mol.Biol., 370, 2007
2P5S
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BU of 2p5s by Molmil
RAB domain of human RASEF in complex with GDP
Descriptor: GUANOSINE-5'-DIPHOSPHATE, RAS and EF-hand domain containing, UNKNOWN ATOM OR ION
Authors:Zhu, H, Wang, J, Shen, Y, Tempel, W, Landry, R, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC)
Deposit date:2007-03-16
Release date:2007-03-27
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:RAB domain of human RASEF in complex with GDP
To be Published
2P5T
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BU of 2p5t by Molmil
Molecular and structural characterization of the PezAT chromosomal toxin-antitoxin system of the human pathogen Streptococcus pneumoniae
Descriptor: PezT, Putative transcriptional regulator PezA, fragment of PezA helix-turn-helix motif
Authors:Loll, B, Meinhart, A.
Deposit date:2007-03-16
Release date:2007-05-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Molecular and Structural Characterization of the PezAT Chromosomal Toxin-Antitoxin System of the Human Pathogen Streptococcus pneumoniae.
J.Biol.Chem., 282, 2007
2P5U
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BU of 2p5u by Molmil
Crystal structure of Thermus thermophilus HB8 UDP-glucose 4-epimerase complex with NAD
Descriptor: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, UDP-glucose 4-epimerase
Authors:Fu, Z.-Q, Chen, L, Ebihara, A, Shinkai, A, Kuramitsu, S, Yokoyama, S, Zhao, M, Dillard, B, Chrzas, J, Rose, J.P, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG), RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-03-16
Release date:2007-04-17
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Crystal structure of Thermus thermophilus HB8 UDP-glucose 4-epimerase complex with NAD
To be Published

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