Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

7DVO
DownloadVisualize
BU of 7dvo by Molmil
Structure of Reaction Intermediate of Cytochrome P450 NO Reductase (P450nor) Determined by XFEL
Descriptor: GLYCEROL, NADP nitrous oxide-forming nitric oxide reductase, NITRIC OXIDE, ...
Authors:Nomura, T, Kimura, T, Kanematsu, Y, Yamashita, K, Hirata, K, Ueno, G, Murakami, H, Hisano, T, Yamagiwa, R, Takeda, H, Gopalasingam, C, Yuki, K, Kousaka, R, Yanagasawa, S, Shoji, O, Kumasaka, T, Takano, Y, Ago, H, Yamamoto, M, Sugimoto, H, Tosha, T, Kubo, M, Shiro, Y.
Deposit date:2021-01-14
Release date:2021-05-19
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Short-lived intermediate in N 2 O generation by P450 NO reductase captured by time-resolved IR spectroscopy and XFEL crystallography.
Proc.Natl.Acad.Sci.USA, 118, 2021
7EGN
DownloadVisualize
BU of 7egn by Molmil
Crystal structure of the P450 BM3 heme domain mutant F87A in complex with N-imidazolyl-hexanoyl-L-phenylalanine and hydroxylamine
Descriptor: (2S)-2-(6-imidazol-1-ylhexanoylamino)-3-phenyl-propanoic acid, Bifunctional cytochrome P450/NADPH--P450 reductase, GLYCEROL, ...
Authors:Jiang, Y, Dong, S, Feng, Y, Cong, Z.
Deposit date:2021-03-24
Release date:2021-08-18
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:H-Bonding Networks Dictate the Molecular Mechanism of H2O2 Activation by P450
Acs Catalysis, 11, 2021
7CCF
DownloadVisualize
BU of 7ccf by Molmil
Mechanism insights on steroselective oxidation of phosphorylated ethylphenols with cytochrome P450 CreJ
Descriptor: (3-ethylphenyl) dihydrogen phosphate, Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE
Authors:Dong, S, Du, L, Li, S.Y, Feng, Y.G.
Deposit date:2020-06-17
Release date:2021-03-17
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Basis for Selective Oxidation of Phosphorylated Ethylphenols by Cytochrome P450 Monooxygenase CreJ.
Appl.Environ.Microbiol., 87, 2021
7E7F
DownloadVisualize
BU of 7e7f by Molmil
Human CYP11B1 mutant in complex with metyrapone
Descriptor: CHOLIC ACID, Cytochrome P450 11B1, mitochondrial, ...
Authors:Mukai, K, Sugimoto, H, Reiko, S, Matsuura, T, Hishiki, T, Kagawa, N.
Deposit date:2021-02-26
Release date:2022-01-05
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Spatially restricted substrate-binding site of cortisol-synthesizing CYP11B1 limits multiple hydroxylations and hinders aldosterone synthesis.
Curr Res Struct Biol, 3, 2021
7E46
DownloadVisualize
BU of 7e46 by Molmil
Structure of the CYP102A1 Haem Domain with N-Carboxybenzyl-L-Prolyl-L-Phenylalanine in complex with (S)-(-)-1-Phenylethylamine
Descriptor: (1S)-1-phenylethanamine, (2S)-3-phenyl-2-[[(2S)-1-phenylmethoxycarbonylpyrrolidin-2-yl]carbonylamino]propanoic acid, Bifunctional cytochrome P450/NADPH--P450 reductase, ...
Authors:Stanfield, J.K, Sugimoto, H, Shoji, O.
Deposit date:2021-02-10
Release date:2022-02-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Structure of the CYP102A1 Haem Domain with N-Carboxybenzyl-L-Prolyl-L-Phenylalanine in complex with (S)-(-)-1-Phenylethylamine at 1.91 Angstrom Resolution
To Be Published
7F3H
DownloadVisualize
BU of 7f3h by Molmil
Crystal structure of cytochrome P450DA heme domain
Descriptor: Bifunctional cytochrome P450/NADPH--P450 reductase, PROTOPORPHYRIN IX CONTAINING FE, SERINE, ...
Authors:Wan, N.W.
Deposit date:2021-06-16
Release date:2021-07-28
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Directed evolution of cytochrome P450DA hydroxylase activity for stereoselective biohydroxylation
Catalysis Science And Technology, 12, 2022
5FOI
DownloadVisualize
BU of 5foi by Molmil
Crystal structure of mycinamicin VIII C21 methyl hydroxylase MycCI from Micromonospora griseorubida bound to mycinamicin VIII
Descriptor: GLYCEROL, MYCINAMICIN VIII C21 METHYL HYDROXYLASE, Mycinamicin VIII, ...
Authors:Demars, M, Sheng, F, Podust, L.M, Sherman, D.H.
Deposit date:2015-11-22
Release date:2016-07-27
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Biochemical and Structural Characterization of Mycci, a Versatile P450 Biocatalyst from the Mycinamicin Biosynthetic Pathway.
Acs Chem.Biol., 11, 2016
5VBU
DownloadVisualize
BU of 5vbu by Molmil
Crystal Structure of Human Cytochrome P450 21A2 Hydroxyprogesterone Complex
Descriptor: (9beta)-17-hydroxypregn-4-ene-3,20-dione, Cytochrome P450 21-hydroxylase, PROTOPORPHYRIN IX CONTAINING FE
Authors:Pallan, P.S, Egli, M.
Deposit date:2017-03-30
Release date:2017-05-31
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (3.31 Å)
Cite:Functional analysis of human cytochrome P450 21A2 variants involved in congenital adrenal hyperplasia.
J. Biol. Chem., 292, 2017
5GNL
DownloadVisualize
BU of 5gnl by Molmil
Cytochrome P450 Vdh (CYP107BR1) F106V mutant
Descriptor: 2-(2-METHOXYETHOXY)ETHANOL, PROTOPORPHYRIN IX CONTAINING FE, Vitamin D(3) 25-hydroxylase
Authors:Yasutake, Y, Tamura, T.
Deposit date:2016-07-22
Release date:2017-05-17
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural insights into the mechanism of the drastic changes in enzymatic activity of the cytochrome P450 vitamin D3 hydroxylase (CYP107BR1) caused by a mutation distant from the active site
Acta Crystallogr F Struct Biol Commun, 73, 2017
1EHE
DownloadVisualize
BU of 1ehe by Molmil
CRYSTAL STRUCTURES OF CYTOCHROME P450NOR AND ITS MUTANTS (SER286 VAL, THR) IN THE FERRIC RESTING STATE AT CRYOGENIC TEMPERATURE: A COMPARATIVE ANALYSIS WITH MONOOXYGENASE CYTOCHROME P450S
Descriptor: CYTOCHROME P450NOR, PROTOPORPHYRIN IX CONTAINING FE
Authors:Shimizu, H, Park, S.
Deposit date:2000-02-21
Release date:2000-08-21
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structures of cytochrome P450nor and its mutants (Ser286-->Val, Thr) in the ferric resting state at cryogenic temperature: a comparative analysis with monooxygenase cytochrome P450s.
J.Inorg.Biochem., 81, 2000
5G5J
DownloadVisualize
BU of 5g5j by Molmil
Crystal structure of human CYP3A4 bound to metformin
Descriptor: CYTOCHROME P450 3A4, Metformin, PROTOPORPHYRIN IX CONTAINING FE
Authors:Sevrioukova, I.
Deposit date:2016-05-25
Release date:2017-06-07
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Heme Binding Biguanides Target Cytochrome P450-Dependent Cancer Cell Mitochondria.
Cell Chem Biol, 24, 2017
5VWS
DownloadVisualize
BU of 5vws by Molmil
Ligand free structure of Cytochrome P450 TbtJ1
Descriptor: Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE
Authors:Gober, J.G, Ghodge, S.V, Brustad, E.M, Bowers, A.A.
Deposit date:2017-05-22
Release date:2017-06-07
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.411 Å)
Cite:P450-Mediated Non-natural Cyclopropanation of Dehydroalanine-Containing Thiopeptides.
ACS Chem. Biol., 12, 2017
1F24
DownloadVisualize
BU of 1f24 by Molmil
CRYSTAL STRUCTURE OF NO COMPLEX OF THR243ALA MUTANTS OF CYTOCHROME P450NOR
Descriptor: GLYCEROL, NITRIC OXIDE, NITRIC OXIDE REDUCTASE, ...
Authors:Shimizu, H, Park, S.-Y.
Deposit date:2000-05-23
Release date:2000-11-23
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Mutation effects of a conserved threonine (Thr243) of cytochrome P450nor on its structure and function.
J.Inorg.Biochem., 82, 2000
1F25
DownloadVisualize
BU of 1f25 by Molmil
CRYSTAL STRUCTURE OF NO COMPLEX OF THR243ASN MUTANTS OF CYTOCHROME P450NOR
Descriptor: GLYCEROL, NITRIC OXIDE, NITRIC OXIDE REDUCTASE, ...
Authors:Shimizu, H, Park, S.-Y.
Deposit date:2000-05-23
Release date:2000-11-23
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Mutation effects of a conserved threonine (Thr243) of cytochrome P450nor on its structure and function.
J.Inorg.Biochem., 82, 2000
1F26
DownloadVisualize
BU of 1f26 by Molmil
CRYSTAL STRUCTURE OF NO COMPLEX OF THR243VAL MUTANTS OF CYTOCHROME P450NOR
Descriptor: GLYCEROL, NITRIC OXIDE, NITRIC OXIDE REDUCTASE, ...
Authors:Shimizu, H, Park, S.-Y.
Deposit date:2000-05-23
Release date:2000-11-23
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Mutation effects of a conserved threonine (Thr243) of cytochrome P450nor on its structure and function.
J.Inorg.Biochem., 82, 2000
1F4U
DownloadVisualize
BU of 1f4u by Molmil
THERMOPHILIC P450: CYP119 FROM SULFOLOBUS SOLFACTARICUS
Descriptor: CYTOCHROME P450 119, IMIDAZOLE, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Yano, J.K, Koo, L.S, Schuller, D.J, Li, H, Ortiz de Montellano, P.R, Poulos, T.L.
Deposit date:2000-06-09
Release date:2000-10-23
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Crystal structure of a thermophilic cytochrome P450 from the archaeon Sulfolobus solfataricus.
J.Biol.Chem., 275, 2000
5GWE
DownloadVisualize
BU of 5gwe by Molmil
cytochrome P450 CREJ
Descriptor: (4-methylphenyl) dihydrogen phosphate, Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Dong, S, liu, X, Wang, X, Feng, Y.
Deposit date:2016-09-11
Release date:2017-07-12
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Selective oxidation of aliphatic C-H bonds in alkylphenols by a chemomimetic biocatalytic system
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5H1Z
DownloadVisualize
BU of 5h1z by Molmil
CYP153D17 from Sphingomonas sp. PAMC 26605
Descriptor: DODECANE, PROTOPORPHYRIN IX CONTAINING FE, putative CYP alkane hydroxylase CYP153D17
Authors:Lee, C.W, Lee, J.H.
Deposit date:2016-10-13
Release date:2017-01-11
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal Structure of a Putative Cytochrome P450 Alkane Hydroxylase (CYP153D17) from Sphingomonas sp. PAMC 26605 and Its Conformational Substrate Binding
Int J Mol Sci, 17, 2016
1H5Z
DownloadVisualize
BU of 1h5z by Molmil
CYTOCHROME P450 14 ALPHA-STEROL DEMETHYLASE (CYP51) FROM MYCOBACTERIUM TUBERCULOSIS IN FERRIC LOW-SPIN STATE
Descriptor: CYTOCHROME P450 51, FE (II) ION, PROTOPORPHYRIN IX CONTAINING FE
Authors:Podust, L.M, Arase, M, Waterman, M.R.
Deposit date:2001-05-31
Release date:2003-10-03
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Estriol Bound and Ligand-Free Structures of Sterol 14Alpha-Demethylase.
Structure, 12, 2004
5VC0
DownloadVisualize
BU of 5vc0 by Molmil
Crystal structure of human CYP3A4 bound to ritonavir
Descriptor: Cytochrome P450 3A4, PROTOPORPHYRIN IX CONTAINING FE, RITONAVIR
Authors:Sevrioukova, I.
Deposit date:2017-03-30
Release date:2017-05-31
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:High-Level Production and Properties of the Cysteine-Depleted Cytochrome P450 3A4.
Biochemistry, 56, 2017
5VCE
DownloadVisualize
BU of 5vce by Molmil
Crystal structure of the cysteine depleted CYP3A4 bound to ritonavir
Descriptor: Cytochrome P450 3A4, PROTOPORPHYRIN IX CONTAINING FE, RITONAVIR
Authors:Sevrioukova, I.
Deposit date:2017-03-31
Release date:2017-05-31
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:High-Level Production and Properties of the Cysteine-Depleted Cytochrome P450 3A4.
Biochemistry, 56, 2017
5W0C
DownloadVisualize
BU of 5w0c by Molmil
Cytochrome P450 (CYP) 2C9 TCA007 Inhibitor Complex
Descriptor: Cytochrome P450 2C9, GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Johnson, E.F, Hsu, M.-H.
Deposit date:2017-05-30
Release date:2017-09-13
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.001 Å)
Cite:Determinants of the Inhibition of DprE1 and CYP2C9 by Antitubercular Thiophenes.
Angew. Chem. Int. Ed. Engl., 56, 2017
5X24
DownloadVisualize
BU of 5x24 by Molmil
Crystal structure of CYP2C9 genetic variant I359L (*3) in complex with multiple losartan molecules
Descriptor: Cytochrome P450 2C9, PHOSPHATE ION, POTASSIUM ION, ...
Authors:Maekawa, K, Adachi, M, Shah, M.B.
Deposit date:2017-01-30
Release date:2017-10-25
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Structural Basis of Single-Nucleotide Polymorphisms in Cytochrome P450 2C9
Biochemistry, 56, 2017
5HDI
DownloadVisualize
BU of 5hdi by Molmil
Structural characterization of CYP144A1, a Mycobacterium tuberculosis cytochrome P450
Descriptor: Cytochrome P450 144, PROTOPORPHYRIN IX CONTAINING FE
Authors:Chenge, J, Driscoll, M.D, McLean, K.J, Munro, A.W, Leys, D.
Deposit date:2016-01-05
Release date:2016-05-04
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Structural characterization of CYP144A1 - a cytochrome P450 enzyme expressed from alternative transcripts in Mycobacterium tuberculosis.
Sci Rep, 6, 2016
5HH3
DownloadVisualize
BU of 5hh3 by Molmil
OxyA from Actinoplanes teichomyceticus
Descriptor: ACETATE ION, GLYCEROL, OxyA protein, ...
Authors:Haslinger, K, Cryle, M.J.
Deposit date:2016-01-09
Release date:2016-02-10
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of OxyAtei : completing our picture of the glycopeptide antibiotic producing Cytochrome P450 cascade.
Febs Lett., 590, 2016

221371

건을2024-06-19부터공개중

PDB statisticsPDBj update infoContact PDBjnumon