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6WG2
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BU of 6wg2 by Molmil
Crystal structure of Fab239 in complex with NPNA4 peptide from circumsporozoite protein
Descriptor: Fab239 heavy chain, Fab239 light chain, NPNA4 peptide
Authors:Pholcharee, T, Oyen, D, Wilson, I.A.
Deposit date:2020-04-04
Release date:2020-07-29
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.534 Å)
Cite:Structural and biophysical correlation of anti-NANP antibodies with in vivo protection against P. falciparum.
Nat Commun, 12, 2021
4OAW
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BU of 4oaw by Molmil
Fab structure of anti-HIV gp120 V2 mAb 2158
Descriptor: GLYCEROL, Heavy chain of Fab fragment of anti-HIV1 gp120 V2 mAb 2158, Light chain of Fab fragment of anti-HIV1 gp120 V2 mAb 2158, ...
Authors:Spurrier, B.R, Kong, X.P.
Deposit date:2014-01-06
Release date:2014-03-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Functional Implications of the Binding Mode of a Human Conformation-Dependent V2 Monoclonal Antibody against HIV.
J.Virol., 88, 2014
5VPL
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BU of 5vpl by Molmil
CRYSTAL STRUCTURE OF DER F 1 COMPLEXED WITH FAB 4C1
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4C1 - HEAVY CHAIN, ...
Authors:Chruszcz, M, Vailes, L.D, Chapman, M.D, Pomes, A, Minor, W.
Deposit date:2017-05-05
Release date:2017-05-24
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Molecular Determinants For Antibody Binding On Group 1 House Dust Mite Allergens.
J.Biol.Chem., 287, 2012
6WFZ
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BU of 6wfz by Molmil
Crystal structure of Fab399 in complex with NPNA3 peptide from circumsporozoite protein
Descriptor: Fab399 heavy chain, Fab399 light chain, NPNA3 peptide
Authors:Pholcharee, T, Oyen, D, Wilson, I.A.
Deposit date:2020-04-04
Release date:2020-07-29
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Structural and biophysical correlation of anti-NANP antibodies with in vivo protection against P. falciparum.
Nat Commun, 12, 2021
6WFY
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BU of 6wfy by Molmil
Crystal structure of Fab224 in complex with NPNA4 peptide from circumsporozoite protein
Descriptor: Fab224 heavy chain, Fab224 light chain, NPNA4 peptide
Authors:Pholcharee, T, Oyen, D, Wilson, I.A.
Deposit date:2020-04-04
Release date:2020-07-29
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.226 Å)
Cite:Structural and biophysical correlation of anti-NANP antibodies with in vivo protection against P. falciparum.
Nat Commun, 12, 2021
5WK3
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BU of 5wk3 by Molmil
CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN CCL17 AND M116 FAB
Descriptor: C-C motif chemokine 17, GLYCEROL, M116 HEAVY CHAIN, ...
Authors:Teplyakov, A, Obmolova, G, Gilliland, G.L.
Deposit date:2017-07-24
Release date:2017-12-20
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural insights into chemokine CCL17 recognition by antibody M116.
Biochem Biophys Rep, 13, 2018
6RSY
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BU of 6rsy by Molmil
The complex between TCR a7b2 and human Class I MHC HLA-A0201-WT1 with the bound RMFPNAPYL peptide.
Descriptor: 1,2-ETHANEDIOL, ARG-MET-PHE-PRO-ASN-ALA-PRO-TYR-LEU, Beta-2-microglobulin, ...
Authors:Srikannathasan, V, Robinson, R.A.
Deposit date:2019-05-22
Release date:2020-04-15
Last modified:2020-05-13
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Specificity of bispecific T cell receptors and antibodies targeting peptide-HLA.
J.Clin.Invest., 130, 2020
8R8K
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BU of 8r8k by Molmil
XBB-4 Fab in complex with SARS-CoV-2 BA.2.12.1 Spike Glycoprotein
Descriptor: Spike glycoprotein, XBB-4 Fab Heavy chain, XBB-4 Fab Light chain
Authors:Duyvesteyn, H.M.E, Ren, J, Stuart, D.I.
Deposit date:2023-11-29
Release date:2024-05-08
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.41 Å)
Cite:A structure-function analysis shows SARS-CoV-2 BA.2.86 balances antibody escape and ACE2 affinity.
Cell Rep Med, 5, 2024
7JP4
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BU of 7jp4 by Molmil
Crystal structure of a refolded head domain hemagglutinin HA from Influenza A virus A/Fort Monmouth/1/1947
Descriptor: 3[N-MORPHOLINO]PROPANE SULFONIC ACID, Hemagglutinin
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2020-08-07
Release date:2021-01-27
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural characterisation of hemagglutinin from seven Influenza A H1N1 strains reveal diversity in the C05 antibody recognition site.
Sci Rep, 13, 2023
6SNC
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BU of 6snc by Molmil
crystal structure of LN01 Fab in complex with an HIV-1 gp41 peptide
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, LNO1 Heavy Chain, ...
Authors:Caillat, C, Pinto, D, Corti, D, Fenwick, C, Pantaleo, G, Weissenhorn, W.
Deposit date:2019-08-23
Release date:2019-11-06
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural Basis for Broad HIV-1 Neutralization by the MPER-Specific Human Broadly Neutralizing Antibody LN01.
Cell Host Microbe, 26, 2019
5X4G
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BU of 5x4g by Molmil
Crystal structure of Fab fragment of anti-CD147 monoclonal antibody 6H8
Descriptor: 6H8 Fab heavy chain, 6H8 Fab light chain
Authors:Lin, P, Zhang, M.-Y, Chen, X, Ye, S, Yu, X.-L, Zhang, R.-G, Zhu, P, Chen, Z.-N.
Deposit date:2017-02-13
Release date:2018-01-24
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Crystal structure of CD147 C2 domain in complex with Fab of its monoclonal antibody
To Be Published
7S4S
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BU of 7s4s by Molmil
Crystal Structure of SARS-CoV-2 S receptor-binding domain (RBD) in complex CoV11 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, CoV11 heavy chain, ...
Authors:Tolbert, W.D, Pazgier, M.
Deposit date:2021-09-09
Release date:2021-09-22
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:The molecular basis of the neutralization breadth of the RBD-specific antibody CoV11.
Front Immunol, 14, 2023
8EDF
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BU of 8edf by Molmil
Bovine Fab SKD in complex with Sars COV-2 receptor binding domain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, SKD Fab Light chain, SKD Fab heavy chain, ...
Authors:Stanfield, R.L, Wilson, I.A.
Deposit date:2022-09-04
Release date:2023-09-20
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:The smallest functional antibody fragment: Ultralong CDR H3 antibody knob regions potently neutralize SARS-CoV-2.
Proc.Natl.Acad.Sci.USA, 120, 2023
8ECZ
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BU of 8ecz by Molmil
Bovine Fab 4C1
Descriptor: 4C1 Fab heavy chain, 4C1 Fab light chain, PHOSPHATE ION
Authors:Stanfield, R.L, Wilson, I.A.
Deposit date:2022-09-02
Release date:2023-09-20
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:The smallest functional antibody fragment: Ultralong CDR H3 antibody knob regions potently neutralize SARS-CoV-2.
Proc.Natl.Acad.Sci.USA, 120, 2023
8ECQ
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BU of 8ecq by Molmil
Bovine Fab 2G3
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2G3 Fab Heavy chain, 2G3 Fab Light chain, ...
Authors:Stanfield, R.L, Wilson, I.A.
Deposit date:2022-09-02
Release date:2023-09-20
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:The smallest functional antibody fragment: Ultralong CDR H3 antibody knob regions potently neutralize SARS-CoV-2.
Proc.Natl.Acad.Sci.USA, 120, 2023
8ECV
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BU of 8ecv by Molmil
Bovine Fab 2F12
Descriptor: 2F12 Fab Heavy chain, 2F12 Fab Light chain
Authors:Stanfield, R.L, Wilson, I.A.
Deposit date:2022-09-02
Release date:2023-09-20
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:The smallest functional antibody fragment: Ultralong CDR H3 antibody knob regions potently neutralize SARS-CoV-2.
Proc.Natl.Acad.Sci.USA, 120, 2023
8ED1
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BU of 8ed1 by Molmil
Bovine Fab 5C1
Descriptor: 5C1 Fab heavy chain, 5C1 Fab light chain, GLYCEROL, ...
Authors:Stanfield, R.L, Wilson, I.A.
Deposit date:2022-09-02
Release date:2023-09-20
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:The smallest functional antibody fragment: Ultralong CDR H3 antibody knob regions potently neutralize SARS-CoV-2.
Proc.Natl.Acad.Sci.USA, 120, 2023
6T3O
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BU of 6t3o by Molmil
Crystal structure of the human myomesin domain 10
Descriptor: AZIDE ION, Myomesin-1
Authors:Duskova, J, Petrokova, H, Maly, P.
Deposit date:2019-10-11
Release date:2021-03-17
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Myomedin scaffold variants targeted to 10E8 HIV-1 broadly neutralizing antibody mimic gp41 epitope and elicit HIV-1 virus-neutralizing sera in mice.
Virulence, 12, 2021
5X0T
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BU of 5x0t by Molmil
Crystal structure of CD147 C2 domain in complex with Fab of its monoclonal antibody 6H8
Descriptor: 6H8 Fab fragment heavy chain, 6H8 Fab fragment light chain, Basigin
Authors:Lin, P, Zhang, M.-Y, Ye, S, Chen, X, Yu, X.-L, Zhang, R.-G, Zhu, P, Chen, Z.-N.
Deposit date:2017-01-23
Release date:2018-01-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of CD147 C2 domain in complex with Fab of its monoclonal antibody
To Be Published
4O5N
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BU of 4o5n by Molmil
Crystal structure of A/Victoria/361/2011 (H3N2) influenza virus hemagglutinin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ...
Authors:Lee, P.S, Wilson, I.A.
Deposit date:2013-12-19
Release date:2014-04-16
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Receptor mimicry by antibody F045-092 facilitates universal binding to the H3 subtype of influenza virus.
Nat Commun, 5, 2014
8Q5U
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BU of 8q5u by Molmil
Endoglycosidase S2 in complex with IgG1 Fc
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Sudol, A.S.L, Tews, I, Crispin, M.
Deposit date:2023-08-09
Release date:2024-04-17
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3 Å)
Cite:The IgG-specific endoglycosidases EndoS and EndoS2 are distinguished by conformation and antibody recognition.
J.Biol.Chem., 300, 2024
5XRS
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BU of 5xrs by Molmil
Crystal structure of A/Minnesota/11/2010 (H3N2) influenza virus hemagglutinin in complex with LSTc
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CACODYLATE ION, ...
Authors:Zhang, H, Wilson, I.A.
Deposit date:2017-06-09
Release date:2018-07-25
Last modified:2022-10-12
Method:X-RAY DIFFRACTION (2.907 Å)
Cite:A multifunctional human monoclonal neutralizing antibody that targets a unique conserved epitope on influenza HA.
Nat Commun, 9, 2018
5XRT
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BU of 5xrt by Molmil
Crystal structure of A/Minnesota/11/2010 (H3N2) influenza virus hemagglutinin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Zhang, H, Wilson, I.A.
Deposit date:2017-06-09
Release date:2018-07-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:A multifunctional human monoclonal neutralizing antibody that targets a unique conserved epitope on influenza HA.
Nat Commun, 9, 2018
7JPD
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BU of 7jpd by Molmil
Crystal structure of the trimeric full length mature hemagglutinin from influenza A virus A/Fort Monmouth/1/1947
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2020-08-07
Release date:2021-10-06
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structural characterisation of hemagglutinin from seven Influenza A H1N1 strains reveal diversity in the C05 antibody recognition site.
Sci Rep, 13, 2023
5WI9
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BU of 5wi9 by Molmil
Crystal structure of KL with an agonist Fab
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 39F7 Fab heavy chain, ...
Authors:Johnstone, S, Min, X, Wang, Z.
Deposit date:2017-07-18
Release date:2018-07-25
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Agonistic beta-Klotho antibody mimics fibroblast growth factor 21 (FGF21) functions.
J. Biol. Chem., 293, 2018

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