6WFY

Crystal structure of Fab224 in complex with NPNA4 peptide from circumsporozoite protein

Summary for 6WFY

• Entry DOI: 10.2210/pdb6wfy/pdb
• Descriptor: Fab224 heavy chain, Fab224 light chain, NPNA4 peptide, ... (4 entities in total)
• Functional Keywords: malaria, sporozoite, circumsporozoite protein, antibody, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 49163.73

Authors

Pholcharee, T.,Oyen, D.,Wilson, I.A. (deposition date: 2020-04-04, release date: 2020-07-29, Last modification date: 2024-04-03)

• Primary citation: Pholcharee, T.,Oyen, D.,Flores-Garcia, Y.,Gonzalez-Paez, G.,Han, Z.,Williams, K.L.,Volkmuth, W.,Emerling, D.,Locke, E.,Richter King, C.,Zavala, F.,Wilson, I.A.; Structural and biophysical correlation of anti-NANP antibodies with in vivo protection against P. falciparum.; Nat Commun, 12:1063-1063, 2021; PubMed: 33594061; DOI: 10.1038/s41467-021-21221-4

Experimental method

X-RAY DIFFRACTION (1.226 Å)