8EDF

Bovine Fab SKD in complex with Sars COV-2 receptor binding domain

Summary for 8EDF

• Entry DOI: 10.2210/pdb8edf/pdb
• Descriptor: SKD Fab Light chain, SKD Fab heavy chain, Spike protein S1, ... (4 entities in total)
• Functional Keywords: antibody, sars cov-2, immune system
• Biological source: Bos taurus (cattle); More
• Total number of polymer chains: 3
• Total formula weight: 73804.92

Authors

Stanfield, R.L.,Wilson, I.A. (deposition date: 2022-09-04, release date: 2023-09-20, Last modification date: 2023-10-04)

• Primary citation: Huang, R.,Warner Jenkins, G.,Kim, Y.,Stanfield, R.L.,Singh, A.,Martinez-Yamout, M.,Kroon, G.J.,Torres, J.L.,Jackson, A.M.,Kelley, A.,Shaabani, N.,Zeng, B.,Bacica, M.,Chen, W.,Warner, C.,Radoicic, J.,Joh, J.,Dinali Perera, K.,Sang, H.,Kim, T.,Yao, J.,Zhao, F.,Sok, D.,Burton, D.R.,Allen, J.,Harriman, W.,Mwangi, W.,Chung, D.,Teijaro, J.R.,Ward, A.B.,Dyson, H.J.,Wright, P.E.,Wilson, I.A.,Chang, K.O.,McGregor, D.,Smider, V.V.; The smallest functional antibody fragment: Ultralong CDR H3 antibody knob regions potently neutralize SARS-CoV-2.; Proc.Natl.Acad.Sci.USA, 120:e2303455120-e2303455120, 2023; PubMed: 37722054; DOI: 10.1073/pnas.2303455120

Experimental method

X-RAY DIFFRACTION (3.4 Å)