8Q5U

Endoglycosidase S2 in complex with IgG1 Fc

Summary for 8Q5U

• Entry DOI: 10.2210/pdb8q5u/pdb
• Descriptor: Uncharacterized protein DKFZp686C11235, Endo-beta-N-acetylglucosaminidase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• Functional Keywords: antibody, igg, fc, endoglycosidase s2, endos2, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 358341.61

Authors

Sudol, A.S.L.,Tews, I.,Crispin, M. (deposition date: 2023-08-09, release date: 2024-04-17, Last modification date: 2024-05-08)

• Primary citation: Sudol, A.S.L.,Crispin, M.,Tews, I.; The IgG-specific endoglycosidases EndoS and EndoS2 are distinguished by conformation and antibody recognition.; J.Biol.Chem., 300:107245-107245, 2024; PubMed: 38569940; DOI: 10.1016/j.jbc.2024.107245

Experimental method

X-RAY DIFFRACTION (3 Å)