8Q5U
Endoglycosidase S2 in complex with IgG1 Fc
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| D | 0005509 | molecular_function | calcium ion binding |
| D | 0005576 | cellular_component | extracellular region |
| D | 0033925 | molecular_function | mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity |
| D | 0042783 | biological_process | symbiont-mediated evasion of host immune response |
| D | 0043655 | cellular_component | host extracellular region |
| E | 0005509 | molecular_function | calcium ion binding |
| E | 0005576 | cellular_component | extracellular region |
| E | 0033925 | molecular_function | mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity |
| E | 0042783 | biological_process | symbiont-mediated evasion of host immune response |
| E | 0043655 | cellular_component | host extracellular region |
| F | 0005509 | molecular_function | calcium ion binding |
| F | 0005576 | cellular_component | extracellular region |
| F | 0033925 | molecular_function | mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity |
| F | 0042783 | biological_process | symbiont-mediated evasion of host immune response |
| F | 0043655 | cellular_component | host extracellular region |
Functional Information from PROSITE/UniProt
| site_id | PS00290 |
| Number of Residues | 7 |
| Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. FSCSVMH |
| Chain | Residue | Details |
| A | PHE423-HIS429 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) (complex) asparagine","evidences":[{"source":"PubMed","id":"19358553","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"29449492","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 307 |
| Details | Domain: {"description":"GH18","evidences":[{"source":"PROSITE-ProRule","id":"PRU01258","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 46 |
| Details | Repeat: {"description":"LRR 1","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 69 |
| Details | Repeat: {"description":"LRR 2","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 69 |
| Details | Repeat: {"description":"LRR 3","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 46 |
| Details | Repeat: {"description":"LRR 4","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 69 |
| Details | Repeat: {"description":"LRR 5","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 308 |
| Details | Region: {"description":"carbohydrate-binding module (CBM)","evidences":[{"source":"UniProtKB","id":"Q99Y92","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"PROSITE-ProRule","id":"PRU10053","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"23865566","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI12 |
| Number of Residues | 18 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"30937380","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6MDS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6MDV","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI13 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"30937380","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6MDV","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI14 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"30937380","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6MDS","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI15 |
| Number of Residues | 18 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"30937380","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6E58","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6MDS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6MDV","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
